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In this paper, we present a mathematical and numerical model for blood solidification and its rupture in stenosed arteries. The interaction between the blood flow and an existing stenosis in the arterial wall is modeled as a three…

Numerical Analysis · Mathematics 2020-05-15 Fatima Abbas , Ayman Mourad

Thrombosis in rotary blood pumps arises from complex flow conditions that remain difficult to translate into reliable and interpretable risk predictions using existing computational models. This limitation reflects an incomplete…

Machine Learning · Computer Science 2025-12-19 Christopher Blum , Michael Neidlin

This paper worked towards modeling blood platelets. Blood platelets, also known as thrombocytes, play a key role in blood clotting which is a vital human function. Furthermore, the role of these entities in strokes, myocardial infarctions,…

Cell Behavior · Quantitative Biology 2012-06-05 Vijay Viswanathan , Seetha Pothapragada

Patient-specific hemodynamics assessment could support diagnosis and treatment of neurovascular diseases. Currently, conventional medical imaging modalities are not able to accurately acquire high-resolution hemodynamic information that…

Intracranial aneurysms (IAs) are serious cerebrovascular lesions found in approximately 5\% of the general population. Their rupture may lead to high mortality. Current methods for assessing IA risk focus on morphological and…

We present a generalizable uncertainty quantification (UQ) and visualization framework for lattice Boltzmann method simulations of high Reynolds number vascular flows, demonstrated on a patient-specific stenosed aorta. The framework…

Many scientific and engineering problems involving multi-physics span a wide range of scales. Understanding the interactions across these scales is essential for fully comprehending such complex problems. However, visualizing multivariate,…

Graphics · Computer Science 2026-02-09 Arisa Cowe , Tyson Neuroth , Qi Wu , Martin Rieth , Jacqueline Chen , Myoungkyu Lee , Kwan-Liu Ma

Investigating blood flow in the cardiovascular system is crucial for assessing cardiovascular health. Computational approaches offer some non-invasive alternatives to measure blood flow dynamics. Numerical simulations based on traditional…

Numerical Analysis · Mathematics 2024-06-07 Han Zhang , Raymond Chan , Xue-Cheng Tai

Reduced-order models based on physics are a popular choice in cardiovascular modeling due to their efficiency, but they may experience reduced accuracy when working with anatomies that contain numerous junctions or pathological conditions.…

Four-dimensional (4D) Flow MRI can noninvasively measure cerebrovascular hemodynamics but remains underused clinically because current workflows rely on manual vessel segmentation and yield velocity fields sensitive to noise, artifacts, and…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Abhishek Singh , Vitaliy L. Rayz , Pavlos P. Vlachos

Accurate characterization of carotid plaques is critical for stroke prevention in patients with carotid stenosis. We analyze 500 plaques from CREST-2, a multi-center clinical trial, to identify radiomics-based markers from B-mode ultrasound…

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

The accurate quantification of blood flow in aortoiliac arteries is challenging but clinically relevant because local flow patterns can influence atherosclerotic disease. To investigate the feasibility and clinical application of…

We discuss the physics of embolic stroke using a minimal model of emboli moving through the cerebral arteries. Our model of the blood flow network consists of a bifurcating tree, into which we introduce particles (emboli) that halt flow on…

Soft Condensed Matter · Physics 2009-11-24 J. P. Hague , E. M. L. Chung

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

We study the question of how visual analysis can support the comparison of spatio-temporal ensemble data of liquid and gas flow in porous media. To this end, we focus on a case study, in which nine different research groups concurrently…

Human-Computer Interaction · Computer Science 2023-11-28 Ruben Bauer , Quynh Quang Ngo , Guido Reina , Steffen Frey , Bernd Flemisch , Helwig Hauser , Thomas Ertl , Michael Sedlmair

Introduction: An approach to building a hybrid simulation of patient flow is introduced with a combination of data-driven methods for automation of model identification. The approach is described with a conceptual framework and basic…

Computers and Society · Computer Science 2020-04-03 Sergey V. Kovalchuk , Anastasia A. Funkner , Oleg G. Metsker , Aleksey N. Yakovlev

Hemostasis and thrombosis are often thought as two sides of the same clotting mechanism whereas hemostasis is a natural protective mechanism to prevent bleeding and thrombosis is a blood clot abnormally formulated inside a blood vessel,…

Tissues and Organs · Quantitative Biology 2019-11-19 Limei Cheng , Guo-Wei Wei , Tarek Leil

Vascular calcification is implicated as an important factor in major adverse cardiovascular events (MACE), including heart attack and stroke. A controversy remains over how to integrate the diverse forms of vascular calcification into…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Mehdi Ramezanpour , Anne M. Robertson , Yasutaka Tobe , Xiaowei Jia , Juan R. Cebral
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