Related papers: Visualizing Carotid Blood Flow Simulations for Str…

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Carotid artery stenosis is the narrowing of carotid arteries, which supplies blood to the neck and head. In this work, we train a model to predict the severity of the stenosis blockage based on SRUC criteria variables and other patient…

Contemporary paradigm of vascular hemodynamics considers normal blood flow to be pulsatile laminar flow. Transition to turbulence can cause diseases such as atherosclerosis or brain aneurysms. Recently, we demonstrated the existence of…

Recently developed methods for rapid continuous volumetric two-photon microscopy facilitate the observation of neuronal activity in hundreds of individual neurons and changes in blood flow in adjacent blood vessels across a large volume of…

Bubbles introduced to the arterial circulation during invasive medical procedures can have devastating consequences for brain function but their effects are currently difficult to quantify. Here we present a Monte-Carlo simulation…

Stroke is the second leading cause of disability worldwide. In order to minimize disability, the goal of stroke treatment is to preserve tissue in the area where blood supply is decreased but sufficient to stave off cell death. Thrombectomy…

There is a need to develop Monte Carlo simulations of stroke to run in-silico trials to replace animal models, explore clinical scenarios to develop hypotheses for clinical studies and for interpreting clinical monitoring. We perform…

Widefield calcium imaging has recently emerged as a powerful experimental technique to record coordinated large-scale brain activity. These measurements present a unique opportunity to characterize spatiotemporal coherent structures that…

Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…

Ischemia leading to heart attacks and strokes is the major cause of deaths in the world. Whether an occlusion occurs or not, depends on the ability of a growing thrombus to resist forces exerted on its structure. This manuscript provides…

A unified Smoothed Particle Hydrodynamics (SPH) simulation framework for coronary stent implantation is developed, which unifies weakly compressible hemodynamics, Neo-Hookean solids, and stent-artery contacts, based on a multi-resolution…

This study investigates the hemodynamic behavior of blood flow in the aortic arch across anemic, diabetic, and healthy conditions using computational fluid dynamics (CFD) simulations with a non-Newtonian Carreau viscosity model. Velocity…

Parametric reduced-order modelling often serves as a surrogate method for hemodynamics simulations to improve the computational efficiency in many-query scenarios or to perform real-time simulations. However, the snapshots of the method…

This work presents a novel and promising approach to the clinical management of acute stroke. Using machine learning techniques, our research has succeeded in developing accurate diagnosis and prediction real-time models from hemodynamic…

Coronary heart disease (CHD) remains a top reason of mortality worldwide. This study introduces a novel approach by integrating patient-specific Multi-slice CT scans into CAD models and employing a one-dimensional numerical framework to…

Prediction of the blood flow characteristics is of utmost importance for understanding the behavior of the blood arterial network, especially in the presence of vascular diseases such as stenosis. Computational fluid dynamics (CFD) has…

In this work, we consider two kinds of model reduction techniques to simulate blood flow through the largest systemic arteries, where a stenosis is located in a peripheral artery i.e. in an artery that is located far away from the heart.…

Atherosclerotic lesions within carotid and cerebral vessels are likely to influence hemodynamics and manifest into vascular pathologies, including Alzheimers Disease and ischemic stroke. Hemodynamics are influenced by changes in luminal…

Cardiovascular diseases are a leading cause of death in the world, driving the development of patient-specific and benchmark models for blood flow analysis. This chapter provides a theoretical overview of the main categories of Reduced…

Deviation of blood flow from an optimal range is known to be associated with the initiation and progression of vascular pathologies. Important open questions remain about how the abnormal flow drives specific wall changes in pathologies…