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Specific elements of viral genomes regulate interactions within host cells. Here, we calculated the secondary structure content of >2500 coronaviruses and computed >100000 human protein interactions with severe acute respiratory syndrome…

Biomolecules · Quantitative Biology 2020-04-30 Andrea Vandelli , Michele Monti , Edoardo Milanetti , Riccardo Delli Ponti , Gian Gaetano Tartaglia

SARS-CoV-2 is a global challenge due to its ability to spread much faster than SARS-CoV, which was attributed to the mutations in the receptor binding domain (RBD). These mutations enhanced the electrostatic interactions. Recently, a new…

Biological Physics · Physics 2021-01-07 Fedaa Ali , Amal Kasry , Muhamed Amin

Disease awareness in infection dynamics can be modeled with adaptive contact networks whose rewiring rules reflect the attempt by susceptibles to avoid infectious contacts. Simulations of this type of models show an active phase with…

Adaptation and Self-Organizing Systems · Physics 2012-12-06 Stefan Wieland , Tomas Aquino , Ana Nunes

A genome, composed of a precisely ordered sequence of four nucleotides (ATCG), encompasses a multitude of specific genome features like AAA motif. Mutations occurring within a genome disrupt the sequential order and composition of these…

Other Quantitative Biology · Quantitative Biology 2024-03-26 Anyou Wang

The discovery of SARS-CoV-2, the responsible virus for the Covid-19 epidemic, has sparked a global health concern with many countries affected. Developing models that can interpret the epidemic and give common trend parameters are useful…

Populations and Evolution · Quantitative Biology 2021-09-21 Milad Radiom , Jean-Franccois Berret

After the blockade that many nations suffered to stop the growth of the incidence curve of COVID-19 during the first half of 2020, they face the challenge of resuming their social and economic activity. The rapid airborne transmissibility…

The investment of time and resources for better strategies and methodologies to tackle a potential pandemic is key to deal with potential outbreaks of new variants or other viruses in the future. In this work, we recreated the scene of a…

Machine Learning · Computer Science 2021-04-22 Andrés L. Suárez-Cetrulo , Ankit Kumar , Luis Miralles-Pechuán

In this paper we analyze the effects of commuting and social inequalities for the epidemic development of the novel coronavirus (COVID-19). With this aim we consider a SEIRD (susceptible, exposed, infected, recovered and dead by disease)…

Populations and Evolution · Quantitative Biology 2020-08-18 João A. M. Gondim , Thiago Yukio Tanaka

COVID-19 pandemic is severely impacting the lives of billions across the globe. Even after taking massive protective measures like nation-wide lockdowns, discontinuation of international flight services, rigorous testing etc., the infection…

Quantitative Methods · Quantitative Biology 2020-08-28 Sayantari Ghosh , Saumik Bhattacharya

At the beginning of 2020 the world has seen the initial outbreak of COVID-19, a disease caused by SARS-CoV2 virus in China. The World Health Organization (WHO) declared this disease as a pandemic on March 11 2020. As the disease spread…

Physics and Society · Physics 2020-07-17 Pitoyo Hartono

COVID-19 is a new pathogen that first appeared in the human population at the end of 2019, and it can lead to novel variants of pneumonia after infection. COVID-19 is a rapidly spreading infectious disease that infects humans faster.…

Image and Video Processing · Electrical Eng. & Systems 2023-02-07 Saddam Hussain Khan

Coinfection is the process by which a host that is infected with a pathogen becomes infected by a second pathogen at a later point in time. An immunosuppressant host response to a primary disease can facilitate spreading of a subsequent…

Physics and Society · Physics 2021-04-14 Peter Mann , Anne Smith , John Mitchell , Simon Dobson

The COVID-19 epidemic has been spreading around the world for nearly three years, and asymptomatic infections have exacerbated the spread of the epidemic. To evaluate the role of asymptomatic infections in the spread of the epidemic, we…

Analysis of PDEs · Mathematics 2022-10-25 ZH. Zhang , XT. Huang , KD. Cheng , CQ. Xu , SB. Guo , XJ. Wang

The new coronavirus known as COVID-19 is spread world-wide since December 2019. Without any vaccination or medicine, the means of controlling it are limited to quarantine and social distancing. Here we study the spatio-temporal propagation…

Physics and Society · Physics 2020-12-02 Bnaya Gross , Zhiguo Zheng , Shiyan Liu , Xiaoqi Chen , Alon Sela , Jianxin Li , Daqing Li , Shlomo Havlin

Antigenic escape constitutes the main mechanism allowing rapidly evolving viruses to achieve endemicity. Beyond granting immune escape, empirical evidence also suggests that mutations of viruses might increase their inter-host…

Populations and Evolution · Quantitative Biology 2025-11-20 David Soriano-Paños

COVID-19, also known as Novel Coronavirus Disease, is a highly contagious disease that first surfaced in China in late 2019. SARS-CoV-2 is a coronavirus that belongs to the vast family of coronaviruses that causes this disease. The sickness…

Image and Video Processing · Electrical Eng. & Systems 2022-04-11 Narayana Darapaneni , Suma Maram , Harpreet Singh , Syed Subhani , Mandeep Kour , Sathish Nagam , Anwesh Reddy Paduri

The widespread availability of large amounts of genomic data on the SARS-CoV-2 virus, as a result of the COVID-19 pandemic, has created an opportunity for researchers to analyze the disease at a level of detail unlike any virus before it.…

Machine Learning · Computer Science 2021-10-20 Zahra Tayebi , Sarwan Ali , Murray Patterson

This work provides an overview on deterministic and stochastic models that have previously been proposed by us to study the transmission dynamics of the Coronavirus Disease 2019 (COVID-19) in Europe and USA. Briefly, we describe realistic…

Populations and Evolution · Quantitative Biology 2022-07-11 Giorgio Sonnino , Philippe Peeters , Pasquale Nardone

Facing a global challenge with over 6.9 million fatalities, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of CoViD-19, demands novel and comprehensive approaches to understand its complex dynamics. This…

Dynamical Systems · Mathematics 2023-06-05 João Paulo Simões Maurício de Carvalho

We study the interplay between epidemic dynamics and human decision making for epidemics that involve reinfection risk; in particular, the susceptible-infected-susceptible (SIS) and the susceptible-infected-recovered-infected (SIRI)…

Systems and Control · Electrical Eng. & Systems 2023-05-31 Abhisek Satapathi , Narendra Kumar Dhar , Ashish R. Hota , Vaibhav Srivastava
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