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The outbreak of coronavirus disease 2019 (COVID-19) has had a significant repercussion on the health, economy, politics and environment, making coronavirus-related issues more complicated and difficult to solve adequately by relying on a…

Digital Libraries · Computer Science 2021-11-09 Yi Zhao , Lifan Liu , Chengzhi Zhang

Treatment protocols, disease understanding, and viral characteristics changed over the course of the COVID-19 pandemic; as a result, the risks associated with patient comorbidities and biomarkers also changed. We add to the conversation…

Machine Learning · Computer Science 2022-11-17 Benjamin Lengerich , Mark E. Nunnally , Yin Aphinyanaphongs , Rich Caruana

The outbreak of novel coronavirus (2019-nCoV) in China has caused a viral epidemic affecting tens of thousands of persons. Though the danger of this epidemic is evident, the statistical analysis of data offered in this paper indicates that…

Populations and Evolution · Quantitative Biology 2020-02-19 Javier Gamero , Juan A. Tamayo , Juan A. Martinez-Roman

In this work, we aim to study that the dynamics behavior for cumulative number of SARS-CoV-2 pandemic can provide information on the overall behavior of the spread over daily time.The cumulative data can be synthesized in an empirical form…

Populations and Evolution · Quantitative Biology 2020-11-16 Hamieh Mohamad , Doumit Mary , Toufaily Joumana , Hamieh Tayssir

Applying a ML approach to the temporal variability of the Spike protein sequence enables us to identify, classify and track emerging virus variants. Our analysis is unbiased, in the sense that it does not require any prior knowledge of the…

Coronavirus, or COVID-19, is a hazardous disease that has endangered the health of many people around the world by directly affecting the lungs. COVID-19 is a medium-sized, coated virus with a single-stranded RNA, and also has one of the…

This paper analyzes a simplified model of viral infection and evolution using the 'grand canonical ensemble' and formalisms from statistical mechanics and thermodynamics to enumerate all possible viruses and to derive thermodynamic…

Populations and Evolution · Quantitative Biology 2016-01-08 Barbara A. Jones , Justin Lessler , Simone Bianco , James H. Kaufman

There is a rich history of models for the interaction of a biological contagion like influenza with the spread of related information such as an influenza vaccination campaign. Recent work on the spread of interacting contagions on networks…

Physics and Society · Physics 2020-09-02 Laurent Hébert-Dufresne , Dina Mistry , Benjamin M. Althouse

The novel coronavirus universally known as the COVID-19 outbreak arises at the end of 2019 in one of the East Asian countries and it is subjected to widespread discussion and debate. There are almost 200 countries affected across the globe…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Kinjal A Patel , Tanvi Goswami

We present a thorough inspection of the dynamical behavior of epidemic phenomena in populations with complex and heterogeneous connectivity patterns. We show that the growth of the epidemic prevalence is virtually instantaneous in all…

Disordered Systems and Neural Networks · Physics 2007-05-23 Marc Barthelemy , Alain Barrat , Romualdo Pastor-Satorras , Alessandro Vespignani

The COVID-19 pandemic is spreading rapidly around the world, causing countries to impose lockdowns and efforts to develop vaccines on a global scale. However, human-to-animal and animal-to-human transmission cannot be ignored, as severe…

Populations and Evolution · Quantitative Biology 2024-08-20 Zi Hian Tan , Kian Yan Yong , Jian-Jun Shu

Motivated by the recent outbreak of coronavirus (COVID-19), we propose a stochastic model of epidemic temporal growth and mitigation based on a time-modulated Hawkes process. The model is sufficiently rich to incorporate specific…

Populations and Evolution · Quantitative Biology 2021-03-18 Michele Garetto , Emilio Leonardi , Giovanni Luca Torrisi

The COVID-19 pandemic has severely impacted health systems and economies worldwide. Significant global efforts are therefore ongoing to improve vaccine efficacies, optimize vaccine deployment, and develop new antiviral therapies to combat…

Populations and Evolution · Quantitative Biology 2021-12-21 Rajat Desikan , Pranesh Padmanabhan , Andrzej M. Kierzek , Piet H. van der Graaf

A two-step contagion model with a single seed serves as a cornerstone for understanding the critical behaviors and underlying mechanism of discontinuous percolation transitions induced by cascade dynamics. When the contagion spreads from a…

Statistical Mechanics · Physics 2017-06-21 Wonjun Choi , Deokjae Lee , B. Kahng

Mathematical models describing SARS-CoV-2 dynamics and the corresponding immune responses in patients with COVID-19 can be critical to evaluate possible clinical outcomes of antiviral treatments. In this work, based on the concept of virus…

We present a differential equations model in which contagious disease transmission is affected by contagious fear of the disease and contagious fear of the control, in this case vaccine. The three contagions are coupled. The two fears…

Populations and Evolution · Quantitative Biology 2021-02-23 Joshua M. Epstein , Erez Hatna , Jennifer Crodelle

The rapid transmission of the highly contagious novel coronavirus has been represented through several data-guided approaches across targeted geographies, in an attempt to understand when the pandemic will be under control and imposed…

Populations and Evolution · Quantitative Biology 2020-05-05 Joydeep Munshi , Indranil Roy , Ganesh Balasubramanian

In this paper we create a compartmental, stochastic process model of SARS-CoV-2 transmission, where the process's mean and variance have distinct dynamics. The model is fit to time series data from Washington from January 2020 to March 2021…

Populations and Evolution · Quantitative Biology 2022-05-05 Niket Thakkar , Mike Famulare

In this work we have investigated the evolutionary dynamics of a generalist pathogen, e.g. a virus population, that evolves towards specialisation in an environment with multiple host types. We have particularly explored under which…

Dynamical Systems · Mathematics 2020-06-24 Anel Nurtay , Matthew G. Hennessy , Lluís Alsedà , Santiago F. Elena , Josep Sardanyés

In individual SARS-CoV-2 outbreaks, the count of confirmed cases and deaths follow a Gompertz growth function for locations of very different sizes. This lack of dependence on region size leads us to hypothesize that virus spread depends on…

Populations and Evolution · Quantitative Biology 2022-01-03 Francesco Zonta , Andrea Scaiewicz , Michael Levitt