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Superparamagnetic iron-oxide nanoparticles (SPIONs) are promising probes for biomedical imaging, but the heterogeneity of their magnetic properties is difficult to characterize with existing methods. Here, we perform widefield imaging of…

We propose Microscopic Propagator Imaging (MPI) as a novel method to retrieve the indices of the microscopic propagator which is the probability density function of water displacements due to diffusion within the nervous tissue…

Neurons and Cognition · Quantitative Biology 2025-03-03 Tommaso Zajac , Gloria Menegaz , Marco Pizzolato

We propose a radical advance in Magnetic Resonance Imaging. MRI remains slow because it requires successive applications of magnetic field gradients to encode for spatial location. Parallel MRI accelerates imaging by permitting…

Medical Physics · Physics 2018-09-19 Michael Hutchinson , Ulrich Raff , Luis Osorio

This paper presents the design and implementation of a magnetic signal scanning and imaging system based on the giant magnetoimpedance (GMI) effect. The system employs a pair of performance-matched GMI sensing elements configured as a…

Instrumentation and Detectors · Physics 2025-11-20 Tao Yang , Zhoulu Yu , Xuekui Xi , Changjun Jiang , Guozhi Chai

Single-pixel imaging (SPI) using a single-pixel detector is an unconventional imaging method, which has great application prospects in many fields to realize high-performance imaging. In especial, the recent proposed catadioptric panoramic…

Optics · Physics 2024-07-30 Huan Cui , Jie Cao , Haoyu Zhang , Chang Zhou , Haifeng Yao , Yingbo Wang , Qun Hao

The development of advanced packaging is essential in the semiconductor manufacturing industry. However, non-destructive testing (NDT) of advanced packaging becomes increasingly challenging due to the depth and complexity of the layers…

Instrumentation and Detectors · Physics 2025-07-17 J. Senthilnath , Jayasanker Jayabalan , Zhuoyi Lin , Aye Phyu Phyu Aung , Chen Hao , Kaixin Xu , Yeow Kheng Lim , F. C. Wellstood

The usually reported pixel resolution of single pixel imaging (SPI) varies between $32 \times 32$ and $256 \times 256$ pixels falling far below imaging standards with classical methods. Low resolution results from the trade-off between the…

Optics · Physics 2022-06-22 Rafał Stojek , Anna Pastuszczak , Piotr Wróbel , Rafał Kotyński

Magnetic Particle Imaging (MPI) is a promising tomographic technique for visualizing the spatio-temporal distribution of superparamagnetic nanoparticles, with applications ranging from cancer detection to real-time cardiovascular…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Vladyslav Gapyak , Thomas März , Andreas Weinmann

The speed and quality of single-pixel imaging (SPI) are fundamentally limited by image modulation frequency and by the levels of optical noise and compression noise. In an approach to come close to these limits, we introduce a SPI…

Optics · Physics 2022-05-25 Anna Pastuszczak , Rafał Stojek , Piotr Wróbel , Rafał Kotyński

This study explores the correlation between iron mass on cell surfaces and the resultant magnetic field. Human colorectal cancer cells (HT29 line) were labeled with varying concentrations of SPIONs and imaged via a NV center widefield…

Magnetic particle imaging (MPI) is a tomographic method to determine the spatio-temporal distribution of magnetic nanoparticles. In this document, a file format for the standardized storage of MPI and magnetic particle spectroscopy (MPS)…

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

Magnetic particle imaging (MPI) is a tracer-based technique that directly detects the distribution of magnetic iron-oxide nanoparticles with millisecond temporal resolution and no tissue background. Despite extensive preclinical work,…

The use of engineered nanoscale magnetic materials in healthcare and biomedical technologies is rapidly growing. Two examples which have recently attracted significant attention are magnetic particle imaging (MPI) for biological monitoring,…

Single-photon emission computed tomography for myocardial perfusion imaging (MPI SPECT) is a widely used diagnostic tool for coronary artery disease. However, the procedure requires considerable scanning time, leading to patient discomfort…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Zezhang Yang , Zitong Yu , Nuri Choi , Janice Tania , Wenxuan Xue , Barry A. Siegel , Abhinav K. Jha

Magnetic resonance imaging (MRI) is a non-invasive and label-free technique widely used in medical diagnosis and life science research, and its success has benefited greatly from continuing efforts on enhancing contrast and resolution. Here…

Detecting spatial and temporal information of individual photons by using single-photon-detector (SPD) arrays is critical to applications in spectroscopy, communication, biological imaging, astronomical observation, and quantum-information…

Magnetic resonance force microscopy (MRFM) is a scanning probe technique capable of detecting MRI signals from nanoscale sample volumes, providing a paradigm-changing potential for structural biology and medical research. Thus far, however,…

Objective: This work introduces a new magnetic particle imaging (MPI) reconstruction framework based on multi-harmonic 3D deconvolution (MH3D) of gridded portraits, offering a principled, model-driven approach to MPI imaging. Approach: MH3D…

Numerical Analysis · Mathematics 2025-10-02 Toby Sanders , Justin J. Konkle , Erica E. Mason , Patrick W. Goodwill

Magnetic resonance imaging (MRI) revolutionized diagnostic medicine and biomedical research by allowing a noninvasive access to spin ensembles. To enhance MRI resolution to the nanometer scale, new approaches including scanning probe…

Mesoscale and Nanoscale Physics · Physics 2019-10-23 Philip Willke , Kai Yang , Yujeong Bae , Andreas J. Heinrich , Christopher P. Lutz