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The Zeeman splitting of a localized single spin can be used to construct a magnetometer allowing high precision measurements of magnetic fields with almost atomic spatial resolution. While sub-{\mu}T sensitivity can in principle be obtained…

Instrumentation and Detectors · Physics 2011-01-28 Rolf Simon Schoenfeld , Wolfgang Harneit

We previously presented a lock-in-amplifier model for analyzing the behavior of signal harmonics in magnetic particle imaging (MPI). In that study, the magnetization and particle size distribution of magnetic nanoparticles (MNPs) were…

Medical Physics · Physics 2019-07-08 Kenya Murase

Superparamagnetic iron oxide nanoparticles (SPIONs) such as ferumoxytol are promising theranostic agents detectable with MRI. Relaxation time mapping offers reproducible, quantitative biomarkers of SPION distribution, but conventional…

The purpose of this study was to present image reconstruction methods for magnetic particle imaging (MPI) with a field-free-line (FFL) encoding scheme and to propose the use of the maximum likelihood-expectation maximization (ML-EM)…

Medical Physics · Physics 2016-06-13 Kenya Murase

Magnetic particle imaging (MPI) is a medical imaging modality of recent origin, and it exploits the nonlinear magnetization phenomenon to recover the spatially dependent concentration of the nanoparticles. Currently, image reconstruction in…

Numerical Analysis · Mathematics 2019-04-23 Tobias Kluth , Bangti Jin

Magnetic particle imaging (MPI) offers exceptional contrast for magnetic nanoparticles (MNP) at high spatio-temporal resolution. A common procedure in MPI starts with a calibration scan to measure the system matrix (SM), which is then used…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Alper Güngör , Baris Askin , Damla Alptekin Soydan , Emine Ulku Saritas , Can Barış Top , Tolga Çukur

We previously developed a system for projection-based magnetic particle imaging (MPI) with a field-free-line (FFL) encoding scheme. In the projection-based MPI, projection data are given by the convolution between the system function in the…

Medical Physics · Physics 2019-07-04 Kenya Murase

We demonstrated a laser depth imaging system based on the time-correlated single-photon counting technique, which was incorporated with a low-jitter superconducting nanowire single-photon detector (SNSPD), operated at the wavelength of 1550…

Optics · Physics 2023-07-19 H. Zhou , Y. He , L. You , S. Chen , W. Zhang , J. Wu , Z. Wang , X. Xie

Magnetic Particle Imaging (MPI) is a promising tracer-based, functional medical imaging technique which measures the non-linear magnetization response of magnetic nanoparticles to a dynamic magnetic field. For image reconstruction, system…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Christina Brandt , Christiane Schmidt

Magnetic Particle Imaging (MPI) is an emerging medical imaging modality that is not yet adopted by clinical practice. Most of the working MPI prototypes including commercial-grade research MPI scanners utilize cylindrical bores that limit…

Medical Physics · Physics 2017-07-13 Alexey Tonyushkin

We demonstrate that the quasistatic recording of the magnetic excitation function M(H) of superparamagnetic iron oxide magnetic nanoparticle (SPION) suspensions by an atomic magnetometer allows a precise determination of the sample's iron…

Atomic Physics · Physics 2016-04-26 Simone Colombo , Victor Lebedev , Zoran D. Grujic , Vladimir Dolgovskiy , Antoine Weis

Magnetic Particle Imaging (MPI) is a recent imaging modality where superparamagnetic nanoparticles are employed as tracers. The reconstruction task is to obtain the spatial particle distribution from a voltage signal induced by the…

Numerical Analysis · Mathematics 2025-08-11 Thomas März , Vladyslav Gapyak , Andreas Weinmann

Purpose: To develop a general framework for Parallel Imaging (PI) with the use of Maxwell regularization for the estimation of the sensitivity maps (SMs) and constrained optimization for the parameter-free image reconstruction. Theory and…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Matteo Alessandro Francavilla , Stamatios Lefkimmiatis , Jorge F. Villena , Athanasios G. Polimeridis

Magnetic Particle Imaging (MPI) is a preclinical imaging technique capable of visualizing the spatio-temporal distribution of magnetic nanoparticles. The image reconstruction of this fast and dynamic process relies on efficiently solving an…

Numerical Analysis · Mathematics 2021-09-15 Florian Lieb , Tobias Knopp

Imaging below the diffraction limit is always a public interest because of the restricted resolution of conventional imaging systems. To beat the limit, evanescent harmonics decaying in space must participate in the imaging process. Here,…

Optics · Physics 2019-10-02 Tie-Jun Huang , Li-Zheng Yin , Ya Shuang , Jiang-Yu Liu , Yunhua Tan , Pu-Kun Liu

Magnetic particle imaging (MPI) is an emerging medical imaging modality which offers a unique combination of high temporal and spatial resolution, sensitivity and biocompatibility. For system-matrix (SM) based image reconstruction in MPI, a…

Software Engineering · Computer Science 2024-01-12 Anselm von Gladiss , Amir Shayan Ahmadian , Jan Jürjens

Magnetic Particle Imaging (MPI) has been shown to provide remarkable contrast for imaging applications such as angiography, stem cell tracking, and cancer imaging. Recently, there is growing interest in the functional imaging capabilities…

Medical Physics · Physics 2017-04-26 Mustafa Utkur , Yavuz Muslu , Emine Ulku Saritas

Two-photon microscopy (2PM) has become an important tool in biology to study the structure and function of intact tissues in-vivo. However, adult mammalian tissues such as the mouse brain are highly scattering, thereby putting fundamental…

Single pixel imaging (SPI) is a novel technique being able to capture 2D images using a bucket detector with high signal-to-noise ratio, wide spectrum range and low cost. Conventional SPI projects random illumination patterns to randomly…

Optics · Physics 2016-07-19 Liheng Bian , Jinli Suo , Xuemei Hu , Feng Chen , Qionghai Dai

Interest in the study of magnetic fields and the properties of interstellar dust, explored through increasingly capable far-IR/submillimeter polarimetry, along with maturing detector technology, have set the stage for a transformative leap…

Instrumentation and Methods for Astrophysics · Physics 2025-09-03 C. Darren Dowell , Brandon S. Hensley , Marc Sauvage