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The transformation of the regular vasculature in normal tissue into a highly inhomogeneous tumor specific capillary network is described by a theoretical model incorporating tumor growth, vessel cooption, neo-vascularization, vessel…

Tissues and Organs · Quantitative Biology 2016-09-08 K. Bartha , H. Rieger

A unified Smoothed Particle Hydrodynamics (SPH) simulation framework for coronary stent implantation is developed, which unifies weakly compressible hemodynamics, Neo-Hookean solids, and stent-artery contacts, based on a multi-resolution…

Fluid Dynamics · Physics 2025-11-13 Jinlei Zhou , Sukang Peng , Yongchuan Yu , Dong Wu , Xiangyu Hu

We derive a full 3-dimensional (3-D) model of inhomogeneous -- anisotropic diffusion in a tumor region coupled to a binary population model. The diffusion tensors are acquired using Diffusion Tensor Magnetic Resonance Imaging (DTI) from a…

Medical Physics · Physics 2021-01-04 Erdi Kara , Aminur Rahman , Eugenio Aulisa , Souparno Ghosh

The incidence of vertebral fragility fracture is increased by the presence of preexisting pathologies such as metastatic disease. Computational tools could support the fracture prediction and consequently the decision of the best medical…

Computational Engineering, Finance, and Science · Computer Science 2024-02-16 Chiara Garavelli , Alessandra Aldieri , Marco Palanca , Enrico Dall'Ara , Marco Viceconti

Real-time surgical phase recognition is a fundamental task in modern operating rooms. Previous works tackle this task relying on architectures arranged in spatio-temporal order, however, the supportive benefits of intermediate spatial…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Xiaojie Gao , Yueming Jin , Yonghao Long , Qi Dou , Pheng-Ann Heng

We derive a one-dimensional (1d) model for the analysis of bulging or necking in an inflated hyperelastic tube of {\it finite wall thickness} from the three-dimensional finite elasticity theory by applying the dimension reduction…

Soft Condensed Matter · Physics 2025-11-21 Xiang Yu , Yibin Fu

Liver cancer is one of the most common malignant diseases in the world. Segmentation and labeling of liver tumors and blood vessels in CT images can provide convenience for doctors in liver tumor diagnosis and surgical intervention. In the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Xiangyu Meng , Xudong Zhang , Gan Wang , Ying Zhang , Xin Shi , Huanhuan Dai , Zixuan Wang , Xun Wang

Machine learning approaches to Structure-Based Drug Design (SBDD) have proven quite fertile over the last few years. In particular, diffusion-based approaches to SBDD have shown great promise. We present a technique which expands on this…

Machine Learning · Computer Science 2024-07-01 Matan Halfon , Eyal Rozenberg , Ehud Rivlin , Daniel Freedman

Most recent unsupervised non-rigid 3D shape matching methods are based on the functional map framework due to its efficiency and superior performance. Nevertheless, respective methods struggle to obtain spatially smooth pointwise…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Dongliang Cao , Zorah Laehner , Florian Bernard

Diffusion models have recently gained popularity for accelerated MRI reconstruction due to their high sample quality. They can effectively serve as rich data priors while incorporating the forward model flexibly at inference time, and they…

Image and Video Processing · Electrical Eng. & Systems 2023-10-20 Batu Ozturkler , Chao Liu , Benjamin Eckart , Morteza Mardani , Jiaming Song , Jan Kautz

We propose a hemodynamic reduced-order model bridging macroscopic and meso-scopic blood flow circulation scales from arteries to capillaries. In silico tree like vascular geometries, mathematically described by graphs, are synthetically…

Medical Physics · Physics 2019-07-29 Olivier Adjoua , Stéphanie Pitre-Champagnat , Didier Lucor

Simulated Moving Bed (SMB) chromatography is a well-known technique for the resolution of several high-value-added compounds. Parameters identification and model topology definition are arduous when one is dealing with complex systems such…

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…

Tissues and Organs · Quantitative Biology 2015-12-22 Richard J. McMurtrey

The immersed boundary (IB) method has been used as a means to simulate fluid-membrane interactions in a wide variety of biological and engineering applications. Although the numerical convergence of the method has been empirically verified,…

Numerical Analysis · Mathematics 2025-10-09 Alexandre X. Milewski , Charles S. Peskin

We propose a computational framework for vascular fluid-structure interaction (FSI), focusing on biomechanical modeling, geometric modeling, and solver technology. The biomechanical model is constructed based on the unified continuum…

Fluid Dynamics · Physics 2022-06-27 Ju Liu , Jiayi Huang , Qingshuang Lu , Yujie Sun

The homography matrix is a key component in various vision-based robotic tasks. Traditionally, homography estimation algorithms are classified into feature- or intensity-based. The main advantages of the latter are their versatility,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Lucas Nogueira , Ely C. de Paiva , Geraldo Silvera

Three-dimensional (3D) cardiovascular fluid dynamics simulations typically require hours to days of computing time on a high-performance computing cluster. One-dimensional (1D) and lumped-parameter zero-dimensional (0D) models show great…

Computational Engineering, Finance, and Science · Computer Science 2022-08-12 Martin R. Pfaller , Jonathan Pham , Aekaansh Verma , Luca Pegolotti , Nathan M. Wilson , David W. Parker , Weiguang Yang , Alison L. Marsden

Learning low-dimensional numerical representations from symbolic data, e.g., embedding the nodes of a graph into a geometric space, is an important concept in machine learning. While embedding into Euclidean space is common, recent…

Machine Learning · Computer Science 2024-10-10 Thomas Bläsius , Jean-Pierre von der Heydt , Maximilian Katzmann , Nikolai Maas

Equivocal 3D lesion segmentation exhibits high inter-observer variability. Conventional deterministic models ignore this aleatoric uncertainty, producing over-confident masks that obscure clinical risks. Conversely, while generative methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Chao Wu , Kangxian Xie , Mingchen Gao