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In this work we investigate the numerical identification of the diffusion coefficient in elliptic and parabolic problems using neural networks. The numerical scheme is based on the standard output least-squares formulation where the…

Numerical Analysis · Mathematics 2023-02-22 Siyu Cen , Bangti Jin , Qimeng Quan , Zhi Zhou

Objective: Innovative therapies such as thermoembolization are expected to play an important role in improvising care for patients with diseases such as hepatocellular carcinoma. Thermoembolization is a minimally invasive strategy that…

This paper deals with the development of a Reduced-Order Model (ROM) to investigate haemodynamics in cardiovascular applications. It employs the use of Proper Orthogonal Decomposition (POD) for the computation of the basis functions and the…

Numerical Analysis · Mathematics 2025-01-24 Pierfrancesco Siena , Pasquale Claudio Africa , Michele Girfoglio , Gianluigi Rozza

We introduce a variant of the Gatenby-Gawlinski model for acid-mediated tumor invasion, accounting for anisotropic and heterogeneous diffusion of the lactic acid across the surrounding healthy tissues. Numerical simulations are performed…

Medical Physics · Physics 2020-06-03 Corrado Mascia , Donato Pera , Chiara Simeoni

Precise molecular subtyping of gliomas, including isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion, directly guides surgical and therapeutic decisions, yet currently relies on invasive tissue sampling. Deep learning on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Han Jang , Junhyeok Lee , Heeseong Eum , Joon Jang , Yoseob Han , Seung Hong Choi , Kyu Sung Choi

Porous and heterogeneous materials are found in many applications from composites, membranes, chemical reactors, and other engineered materials to biological matter and natural subsurface structures. In this work we propose an integrated…

Computational Physics · Physics 2019-09-15 Gianluca Boccardo , Eleonora Crevacore , Alberto Passalacqua , Matteo Icardi

Diffusion models produce high-quality synthetic data but suffer from slow inference. We propose 3D Variable-Step Denoising Diffusion Probabilistic Model (VS-DDPM) a framework engineered to maintain generative quality while accelerating…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Nikoo Moradi , Gijs Luijten , Behrus Hinrichs-Puladi , Jens Kleesiek , Victor Alves , Jan Egger , André Ferreira

Developing efficient path integral (PI) methods for atomistic simulations of vibrational spectra in heterogeneous condensed phases and interfaces has long been a challenging task. Here, we present the h-CMD method, short for hybrid centroid…

Chemical Physics · Physics 2025-05-08 Dil K. Limbu , Nathan London , Md Omar Faruque , Mohammad R. Momeni

Synthetic tumors in medical images offer controllable characteristics that facilitate the training of machine learning models, leading to an improved segmentation performance. However, the existing methods of tumor synthesis yield…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Hongxu Yang , Edina Timko , Levente Lippenszky , Vanda Czipczer , Lehel Ferenczi

A common approach to medical image analysis on volumetric data uses deep 2D convolutional neural networks (CNNs). This is largely attributed to the challenges imposed by the nature of the 3D data: variable volume size, GPU exhaustion during…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Hasib Zunair , Aimon Rahman , Nabeel Mohammed , Joseph Paul Cohen

In this study, we model avascular tumour growth in epithelial tissue. This can help us to get a macroscopic view of the interaction between the tumour with its surrounding microenvironment and the physical changes within the tumour…

Tissues and Organs · Quantitative Biology 2019-05-15 Sounak Sadhukhan , S. K. Basu

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan

The best way to combine the results of deep learning with standard 3D reconstruction pipelines remains an open problem. While systems that pass the output of traditional multi-view stereo approaches to a network for regularisation or…

Computer Vision and Pattern Recognition · Computer Science 2022-07-28 Tristan Laidlow , Jan Czarnowski , Andrea Nicastro , Ronald Clark , Stefan Leutenegger

Diffusion-based image generators can now produce high-quality and diverse samples, but their success has yet to fully translate to 3D generation: existing diffusion methods can either generate low-resolution but 3D consistent outputs, or…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Animesh Karnewar , Niloy J. Mitra , Andrea Vedaldi , David Novotny

An enriched hybrid high-order method is designed for the Stokes equations of fluid flow and is fully applicable to generic curved meshes. Minimal regularity requirements of the enrichment spaces are given, and an abstract error analysis of…

Numerical Analysis · Mathematics 2023-11-23 Liam Yemm

Molecular dynamics (MD) has long been the de facto choice for simulating complex atomistic systems from first principles. Recently deep learning models become a popular way to accelerate MD. Notwithstanding, existing models depend on…

Computational Engineering, Finance, and Science · Computer Science 2023-01-10 Fang Wu , Stan Z. Li

Computational models in cardiac electrophysiology are notorious for long runtimes, restricting the numbers of nodes and mesh elements in the numerical discretisations used for their solution. This makes it particularly challenging to…

We propose a new deep learning method for tumour segmentation when dealing with missing imaging modalities. Instead of producing one network for each possible subset of observed modalities or using arithmetic operations to combine feature…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Reuben Dorent , Samuel Joutard , Marc Modat , Sébastien Ourselin , Tom Vercauteren

We present a novel immersed boundary method that implements acoustic perturbation theory to model an acoustically levitated droplet. Instead of resolving sound waves numerically, our hybrid method solves acoustic scattering…

Soft Condensed Matter · Physics 2024-03-22 Jacqueline B. Sustiel , David G. Grier

In this work, we address the systematic biases and random errors stemming from finite step sizes encountered in diffusion simulations. We introduce the Effective Geometry Monte Carlo (EG-MC) simulation algorithm which modifies the geometry…

Emerging Technologies · Computer Science 2019-06-26 Fatih Dinc , Leander Thiele , Bayram Cevdet Akdeniz