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We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

Machine Learning · Statistics 2022-03-08 Swapneel Mehta , Noah Kasmanoff

This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…

Dynamical Systems · Mathematics 2025-11-18 Kristina Kehrer , Martin Weiser , Tim Conrad

Exploring the spatio-temporal variations of COVID-19 transmission and its potential determinants could provide a deeper understanding of the dynamics of disease spread. This study aims to investigate the spatio-temporal spread of COVID-19…

Applications · Statistics 2023-08-21 Xueqing Yin , John M. Aiken , Richard Harris , Jonathan L. Bamber

To model the evolution of diseases with extended latency periods and the presence of asymptomatic patients like COVID-19, we define a simple discrete time stochastic SIR-type epidemic model. We include both latent periods as well as the…

Populations and Evolution · Quantitative Biology 2020-05-14 Xavier Bardina , Marco Ferrante , Carles Rovira

Analytical descriptions of patterns concerning spread and fatality during an epidemic, covering natural as well as restriction periods, are important for reducing damage. We employ a scaling model to investigate this aspect in the real data…

Physics and Society · Physics 2023-10-25 Subir K. Das

New coronavirus disease (COVID-19) has constituted a global pandemic and has spread to most countries and regions in the world. By understanding the development trend of a regional epidemic, the epidemic can be controlled using the…

Physics and Society · Physics 2020-05-15 Bingjie Yan , Xiangyan Tang , Boyi Liu , Jun Wang , Yize Zhou , Guopeng Zheng , Qi Zou , Yao Lu , Wenxuan Tu

We propose a mathematical model to analyze the time evolution of the total number of infected population with Covid-19 disease at a region in the ongoing pandemic. Using the available data of Covid-19 infected population on various…

Populations and Evolution · Quantitative Biology 2020-08-17 Nilmani Mathur , Gargi Shaw

Biological systems with intertwined feedback loops pose a challenge to mathematical modeling efforts. Moreover, rare events, such as mutation and extinction, complicate system dynamics. Stochastic simulation algorithms are useful in…

Quantitative Methods · Quantitative Biology 2018-12-10 Alfonso Landeros , Timothy Stutz , Kevin L. Keys , Alexander Alekseyenko , Janet S. Sinsheimer , Kenneth Lange , Mary Sehl

We propose a forecasting method for predicting epidemiological health series on a two-week horizon at the regional and interregional resolution. The approach is based on model order reduction of parametric compartmental models, and is…

Methodology · Statistics 2020-12-11 Athmane Bakhta , Thomas Boiveau , Yvon Maday , Olga Mula

We introduce a fast simulation technique for modeling epidemics on adaptive networks. Our rejection-based algorithm efficiently simulates the co-evolution of the network structure and the epidemic dynamics. We extend the classical SIS model…

Social and Information Networks · Computer Science 2024-10-08 Gerrit Großmann , Sebastian Vollmer

As COVID-19 is rapidly spreading across the globe, short-term modeling forecasts provide time-critical information for decisions on containment and mitigation strategies. A main challenge for short-term forecasts is the assessment of key…

Populations and Evolution · Quantitative Biology 2022-11-17 Jonas Dehning , Johannes Zierenberg , F. Paul Spitzner , Michael Wibral , Joao Pinheiro Neto , Michael Wilczek , Viola Priesemann

We propose a novel methodology for estimating the epidemiological parameters of a modified SIRD model (acronym of Susceptible, Infected, Recovered and Deceased individuals) and perform a short-term forecast of SARS-CoV-2 virus spread. We…

We present an interpretable high-resolution spatio-temporal model to estimate COVID-19 deaths together with confirmed cases one-week ahead of the current time, at the county-level and weekly aggregated, in the United States. A notable…

Applications · Statistics 2021-08-24 Shixiang Zhu , Alexander Bukharin , Liyan Xie , Mauricio Santillana , Shihao Yang , Yao Xie

We propose a new stochastic epidemiological model defined in a continuous space of arbitrary dimension, based on SIS dynamics implemented in a spatial $\Lambda$-Fleming-Viot (SLFV) process. The model can be described by as little as three…

Probability · Mathematics 2026-01-09 Apolline Louvet , Bastian Wiederhold

The ongoing Coronavirus Disease 2019 (COVID-19) pandemic threatens the health of humans and causes great economic losses. Predictive modelling and forecasting the epidemic trends are essential for developing countermeasures to mitigate this…

Populations and Evolution · Quantitative Biology 2020-06-01 Ling Xue , Shuanglin Jing , Joel C. Miller , Wei Sun , Huafeng Li , Jose Guillermo Estrada-Franco , James M Hyman , Huaiping Zhu

The objective of this work is to predict the spread of COVID-19 starting from observed data, using a forecast method inspired by probabilistic weather prediction systems operational today. Results show that this method works well for China:…

Applications · Statistics 2020-03-31 Roberto Buizza

A practical introduction to stochastic modelling of reaction-diffusion processes is presented. No prior knowledge of stochastic simulations is assumed. The methods are explained using illustrative examples. The article starts with the…

Subcellular Processes · Quantitative Biology 2007-11-19 Radek Erban , Jonathan Chapman , Philip Maini

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

This paper develops an individual-based stochastic network SIR model for the empirical analysis of the Covid-19 pandemic. It derives moment conditions for the number of infected and active cases for single as well as multigroup epidemic…

Econometrics · Economics 2022-01-05 M. Hashem Pesaran , Cynthia Fan Yang

gemlib is a Python library for defining, simulating, and calibrating Markov state-transition models. Stochastic models are often computationally intensive, making them impractical to use in pandemic response efforts despite their favourable…

Computation · Statistics 2025-11-12 Alin Morariu , Jess Bridgen , Chris Jewell