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Using random walk sampling methods for feature learning on networks, we develop a method for generating low-dimensional node embeddings for directed graphs and identifying transition states of stochastic chemical reacting systems. We…

Numerical Analysis · Mathematics 2020-10-30 Paula Mercurio , Di Liu

Threshold-linear networks are a common class of firing rate models that describe recurrent interactions among neurons. Unlike their linear counterparts, these networks generically possess multiple stable fixed points (steady states), making…

Neurons and Cognition · Quantitative Biology 2016-12-28 Carina Curto , Katherine Morrison

Echo-State Networks (ESNs) distil a key neurobiological insight: richly recurrent but fixed circuitry combined with adaptive linear read-outs can transform temporal streams with remarkable efficiency. Yet fundamental questions about…

Neural and Evolutionary Computing · Computer Science 2025-07-25 Pradeep Singh , Lavanya Sankaranarayanan , Balasubramanian Raman

Zero-one biochemical reaction networks are widely recognized for their importance in analyzing signal transduction and cellular decision-making processes. Degenerate networks reveal non-standard behaviors and mark the boundary where…

Molecular Networks · Quantitative Biology 2025-12-01 Xiaoxian Tang , Yihan Wang , Jiandong Zhang

Large-scale recurrent networks have drawn increasing attention recently because of their capabilities in modeling a large variety of real-world phenomena and physical mechanisms. This paper studies how to identify all authentic connections…

Machine Learning · Statistics 2015-06-23 Yiyuan She , Yuejia He , Dapeng Wu

It is well-known that deep neural networks (DNNs) have shown remarkable success in many fields. However, when adding an imperceptible magnitude perturbation on the model input, the model performance might get rapid decrease. To address this…

Machine Learning · Computer Science 2022-01-04 Hao Yang , Min Wang , Zhengfei Yu , Yun Zhou

Recurrent neural networks with balanced excitation and inhibition exhibit irregular asynchronous dynamics, which is fundamental for cortical computations. Classical balance mechanisms require strong external inputs to sustain finite firing…

Neurons and Cognition · Quantitative Biology 2025-10-21 David Angulo-Garcia , Alessandro Torcini

Increasing availability and quality of actual, as opposed to scheduled, open transport data offers new possibilities for capturing the spatiotemporal dynamics of the railway and other networks of social infrastructure. One way to describe…

Social and Information Networks · Computer Science 2020-12-11 Georg Anagnostopoulos , Vahid Moosavi

We study the model of continuous chemical reaction networks (CRNs), consisting of reactions such as $A+B \to C+D$ that can transform some continuous, nonnegative real-valued quantity (called a *concentration*) of chemical species $A$ and…

Emerging Technologies · Computer Science 2024-11-26 Kim Calabrese , David Doty

Recurrent Neural Cascades (RNCs) are the recurrent neural networks with no cyclic dependencies among recurrent neurons. This class of recurrent networks has received a lot of attention in practice. Besides training methods for a fixed…

Machine Learning · Computer Science 2024-09-09 Nadezda Alexandrovna Knorozova , Alessandro Ronca

This work addresses multistationarity of fully open reaction networks equipped with mass action kinetics. We improve upon the existing results relating existence of positive feedback loops in a reaction network and multistationarity; and we…

Molecular Networks · Quantitative Biology 2025-11-11 Shenghao Yao , AmirHosein Sadeghimanesh , Matthew England

We study an open discrete-time queueing network that models the collection of data in a multi-hop sensor network. We assume data is generated at the sensor nodes as a discrete-time Bernoulli process. All nodes in the network maintain a…

Networking and Internet Architecture · Computer Science 2019-07-26 Iqra Altaf Gillani , Amitabha Bagchi , Pooja Vyavahare

Within a fully microscopic setting, we derive a variational principle for the non-equilibrium steady states of chemical reaction networks, valid for time-scales over which chemical potentials can be taken to be slowly varying: at…

Molecular Networks · Quantitative Biology 2015-06-05 Andrea De Martino , Daniele De Martino , Roberto Mulet , Guido Uguzzoni

We study chemical reaction networks with discrete state spaces, such as the standard continuous time Markov chain model, and present sufficient conditions on the structure of the network that guarantee the system exhibits an extinction…

Dynamical Systems · Mathematics 2017-01-11 Matthew D. Johnston , David F. Anderson , Gheorghe Craciun , Robert Brijder

Reaction networks taken with mass-action kinetics arise in many settings, from epidemiology to population biology to systems of chemical reactions. Bistable reaction networks are posited to underlie biochemical switches, which motivates the…

Dynamical Systems · Mathematics 2016-09-20 Badal Joshi , Anne Shiu

The goal of this paper is to outline a scenario of emerging stochasticity in high-dimensional highly nonlinear systems, such as genetic regulatory networks (GRN). We focus attention on the fact that in such systems confluence of all the…

Molecular Networks · Quantitative Biology 2007-09-19 Simon Rosenfeld

We consider stochastic reaction-diffusion equations on a finite network represented by a finite graph. On each edge in the graph a multiplicative cylindrical Gaussian noise driven reaction-diffusion equation is given supplemented by a…

Probability · Mathematics 2021-06-22 Mihály Kovács , Eszter Sikolya

In this paper I show that, for a class of reaction networks, the discrete stochastic nature of the reacting species and reactions results in qualitative and quantitative differences between the mean of exact stochastic simulations and the…

Other Quantitative Biology · Quantitative Biology 2008-01-03 Chetan J Gadgil

Complex non-linear interactions between banks and assets we model by two time-dependent Erd\H{o}s Renyi network models where each node, representing bank, can invest either to a single asset (model I) or multiple assets (model II). We use…

Risk Management · Quantitative Finance 2015-06-19 B. Podobnik , D. Horvatic , M. Bertella , L. Feng , X. Huang , B. Li

The influence of networks topology on collective properties of dynamical systems defined upon it is studied in the thermodynamic limit. A network model construction scheme is proposed where the number of links, the average eccentricity and…

Physics and Society · Physics 2015-05-25 Sarah De Nigris , Xavier Leoncini