English

Rate-independent continuous inhibitory chemical reaction networks are Turing-universal

Emerging Technologies 2024-11-26 v2

Abstract

We study the model of continuous chemical reaction networks (CRNs), consisting of reactions such as A+BC+DA+B \to C+D that can transform some continuous, nonnegative real-valued quantity (called a *concentration*) of chemical species AA and BB into equal concentrations of CC and DD. Such a reaction can occur from any state in which both reactants AA and BB are present, i.e., have positive concentration. We modify the model to allow *inhibitors*, for instance, reaction A+BIC+DA+B \to^{I} C+D can occur only if the reactants AA and BB are present and the inhibitor II is absent. The computational power of non-inhibitory CRNs has been studied. For instance, the reaction X1+X2YX_1+X_2 \to Y can be thought to compute the function f(x1,x2)=min(x1,x2)f(x_1,x_2) = \min(x_1,x_2). Under an "adversarial" model in which reaction rates can vary arbitrarily over time, it was found that exactly the continuous, piecewise linear functions can be computed, ruling out even simple functions such as f(x)=x2f(x) = x^2. In contrast, in this paper we show that inhibitory CRNs can compute any computable function f:NNf:\mathbb{N}\to\mathbb{N}.

Keywords

Cite

@article{arxiv.2403.07099,
  title  = {Rate-independent continuous inhibitory chemical reaction networks are Turing-universal},
  author = {Kim Calabrese and David Doty},
  journal= {arXiv preprint arXiv:2403.07099},
  year   = {2024}
}