Related papers: Status and development of the TOP-IMPLART Project
Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…
Irradiations at Ultra High Dose Rate (UHDR) regimes, exceeding 40 Gy/s in single fractions lasting less than 200 ms, have shown an equivalent antitumor effect compared to conventional radio-therapy with reduced harm to normal tissues. This…
We investigate the different facets of ion acceleration by a relativistically intense circularly polarized laser pulse interacting with thin near-critical density plasma targets. Our simulations establish that plasma density gradient and…
We present a novel application of Tensor Network methods in cancer treatment as a potential tool to solve the dose optimization problem in radiotherapy. In particular, the Intensity-Modulated Radiation Therapy (IMRT) technique - that allows…
Fermilab has been working with the international particle physics and nuclear physics communities to explore and develop research programs possible with a new high intensity proton source known as "Project-X". Project X will provide…
The article considers an opportunity of simultaneous pulsed acceleration of seven proton beams with current one hundred milliamps in each beam. The accelerator consists of two parts. In the first part of the accelerator having the length…
We are exploring low-dose proton radiography and computed tomography (pCT) as techniques to improve the accuracy of proton treatment planning and to provide artifact-free images for verification and adaptive therapy at the time of…
Conventional cancer therapies include surgery, radiation therapy, chemotherapy, and, more recently, immunotherapy. These modalities are often combined to improve the therapeutic index. The general concept of radiation therapy is to increase…
In this article we present coherent control of above-threshold photoemission from a tungsten nanotip achieving nearly perfect modulation. Depending on the pulse delay between fundamental (1560 nm) and second harmonic (780 nm) pulses of a…
Generation of high-energy proton bunch from interaction of an intense short circularly polarized(CP) laser pulse with a gas-filled cone target(GCT) is investigated using two-dimensional particle-in-cell simulation. The GCT target consists…
In proton therapy, depth scanning of the irradiated object is performed by changing the Output Energy (OE) of the accelerated beam. In pulsed linear accelerators, adjustment of the OE is usually by changing the amplitude and/or phase of the…
A new type of charge-exchange injection scheme for high-intensity proton rings that use a laser beam and an undulator magnet is proposed. The elementary stripping process is resonant photoionization via a broad Stark state formed by the…
Ultra-high dose rate radiation therapy (FLASH) based on proton irradiation is of major interest for cancer treatments but creates new challenges for dose monitoring. Amorphous hydrogenated silicon is known to be one of the most…
We report the experimental results of the commissioning phase in the 10 PW laser beamline of Shanghai Superintense Ultrafast Laser Facility (SULF). The peak power reaches 2.4 PW on target without the last amplifying during the experiment.…
Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-invasive option for such patients. While photon-based STAR has…
SPPC (Super Proton-Proton Collider) is a discovery machine that is designed for energy frontier research in two decades from now, as the second stage of the CEPC-SPPC project. The main objective is to carry out experiments at 125 TeV in…
We demonstrate in this research the quasi-monoenergetic electron and proton acceleration through three dimensional particle-in-cell simulations of short petawatt circular polarized laser pulse interactions with near critical density…
Protontherapy is hadrontherapy fastest-growing modality and a pillar in the battle against cancer. Hadrontherapy superiority lies in its inverted depth-dose profile, hence tumour-confined irradiation. Protons, however, lack distinct…
The purpose of this study was to investigate the feasibility of extracting proton beams with two distinct energies within a single synchrotron cycle. The energy difference between the beams should be sufficient to use one beam as a range…
In this work, we present a fundamental mathematical model for proton transport, tailored to capture the key physical processes underpinning Proton Beam Therapy (PBT). The model provides a robust and computationally efficient framework for…