Related papers: Status and development of the TOP-IMPLART Project
Charged particle therapy (CPT) is an advanced modality of radiation therapy which has grown rapidly worldwide, driven by recent developments in technology and methods of delivery. To ensure safe and high quality treatments, various…
Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…
We present the strategy which has been used recently to optimize integrated luminosity at the Fermilab Tevatron proton-antiproton collider. We use a relatively simple model where we keep the proton intensity fixed, use parameters from fits…
Fusion and advanced fission power plants require advanced nuclear materials to function under new, extreme environments. Understanding the evolution of mechanical and functional properties during radiation damage is essential to the design…
Laser-plasma accelerators represent a promising technology for future compact accelerating systems, enabling the acceleration of tens of pC to above $1\,$GeV over just a few centimeters. Nonetheless, these devices currently lack the…
Ion acceleration in the MeV range can be routinely achieved with table-top laser technology. One of the current challenges is to improve the energy coupling from the laser to the proton beam without increasing the laser peak power.…
A dynamical system model for tumor -- immune system interaction together with a method to mimic radiation therapy are proposed. A large population of virtual patients is simulated following an ideal radiation treatment. A characteristic…
A scheme with gold cone-capillary is proposed to improve the protons acceleration and involved problems are investigated by using the two-dimensional particle-in-cell simulations. It is demonstrated that the cone-capillary can efficiently…
Project Thermalization (Experiment SERP-E-190 at IHEP) is aimed to study the proton - proton interactions at 50 GeV with large number of secondary particles. In this report the experimentally measured topological cross sections are…
Radiation therapy with protons as of today utilizes information from x-ray CT in order to estimate the proton stopping power of the traversed tissue in a patient. The conversion from x-ray attenuation to proton stopping power in tissue…
Standard 6 megavolt (MV) radiotherapy is limited by source size and secondary electron range to minimum radiological penumbra widths of ~2-3 mm. This study investigates sharper beams via upright radiotherapy with lower energies and extended…
We present a novel laser based ion acceleration scheme, where a petawatt circularly polarized laser pulse is shot on an ultra-thin (nano-scale) double-layer target. Our scheme allows the production of high-quality light ion beams with both…
Proton therapy exploits the finite range of charged particles in tissue to achieve dose distributions no photon based modality can replicate. Yet the modality reaches fewer than 1 percent of patients who might benefit a gap rooted in cost…
Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…
We propose a series of simulations about the potential use of Boron isotopes to trigger neutron-free (aneutronic) nuclear reactions in cancer cells through the interaction with an incoming energetic proton beam, thus resulting in the…
The differential sparing of normal tissues relative to tumor control observed at ultra-high dose rates, referred to as the FLASH effect, has recently gained considerable attention. The therapeutic advantages of FLASH radiotherapy are…
Proton radiography is a widely-fielded diagnostic used to measure magnetic structures in plasma. The deflection of protons with multi-MeV kinetic energy by the magnetic fields is used to infer their path-integrated field strength. Here, the…
Proton imaging has become a key diagnostic for measuring electromagnetic fields in high-energy-density (HED) laboratory plasmas. Compared to other techniques for diagnosing fields, proton imaging is a non-perturbative measurement that can…
Theoretical investigations show that linearly and radially polarized multiterawatt and petawatt laser beams, focused to subwavelength waist radii, can directly accelerate protons and carbon nuclei, over micron-size distances, to the…
Today's high-power laser systems are capable of reaching photon intensities up to $10^{22}$ W/cm^2, generating plasmas when interacting with material. The high intensity and ultrashort laser pulse duration (fs) make direct observation of…