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Advances in ultra-intense laser technology are enabling, for the first time, relativistic intensities at mid-infrared (mid-IR) wavelengths. Anticipating further experimental research in this domain, we present high-resolution two…

Fermilab is committed to upgrading its accelerator complex towards the intensity frontier to pursue HEP research in the neutrino sector and beyond. The upgrade has two steps: 1) the Proton Improvement Plan (PIP), which is underway, has its…

Accelerator Physics · Physics 2017-05-04 C. M. Bhat

A 5-MeV RFQ designed for a proton current up to 100-mA CW is now under construction as part of the High Intensity Proton Injector project (IPHI). Its computed transmission is greater than 99 %. The main goals of the project are to verify…

Boron Neutron Capture Therapy (BNCT) is a form of radiotherapy based on the irradiation of the tumour with a low energy neutron beam, after the administration of a selective drug enriched in boron-10. The therapy exploits the high cross…

The advanced imaging and delivery techniques in proton therapy allow conformal high-dose irradiation of the target volume with high accuracy using pencil beam scanning or beam shaping apertures. These irradiation methods increasingly…

An effective scheme of synchronized laser-triggered ion acceleration and the corresponding theoretical model are proposed for a slow light pulse of relativistic intensity, which penetrates into a near-critical-density plasma, strongly…

Plasma Physics · Physics 2016-03-02 A. V. Brantov , E. A. Govras , V. F. Kovalev , V. Yu. Bychenkov

We developed a novel gamma-ray detection system (TIARA) for range monitoring in Particle Therapy. The system employs Cherenkov-based gamma-ray detection modules arranged around the target or patient, operated in time coincidence with a fast…

Purpose: To demonstrate the feasibility of fast Monte Carlo (MC) based inverse biological planning for the treatment of head and neck tumors in spot-scanning proton therapy. Methods: Recently, a fast and accurate Graphics Processor Unit…

Medical Physics · Physics 2016-10-11 H. Wan Chan Tseung , J. Ma , C. R. Kreofsky , D. Ma , C. Beltran

Proton acceleration by ultra-intense laser pulse irradiating a target with cross-section smaller than the laser spot size and connected to a parabolic density channel is investigated. The target splits the laser into two parallel…

Plasma Physics · Physics 2011-12-09 F. L. Zheng , S. Z. Wu , H. C. Wu , H. B. Cai , M. Y. Yu , T. Tajima , X. Q. Yan , X. T. He

We report on an experimental study of proton acceleration by intense laser irradiation of micrometric bar targets, whose dimensions are transversely immersed in the laser focal volume and are longitudinally smaller than half its wavelength.…

We investigate the target normal sheath acceleration of protons in thin aluminum targets irradiated at relativistic intensity by two time-separated ultrashort (35 fs) laser pulses. For identical laser pulses and target thicknesses of 3 and…

Proton therapy is an emerging method in cancer therapy. One of the main developments is to increase the accuracy of the Bragg-peak position calculation, which requires more precise relative stopping power (RSP) measurements. A promising…

Medical Physics · Physics 2026-02-18 Gábor Bíró , Ákos Sudár , Zsófia Jólesz , Gábor Papp , Gergely Gábor Barnaföldi

A new laser-proton acceleration structure combined by two relativistic electron shells, a suprathermal electron shell and a thermal electron cloud is proposed for $a\gtrapprox80\sigma_0$, where a is the normalized laser field and $\sigma_0$…

Plasma Physics · Physics 2011-12-13 Yongsheng Huang , Naiyan Wang , Xiuzhang Tang , Yijin Shi , Zhang Shan

The laser-driven acceleration of high quality proton beams from a double-layer target, comprised of a high-Z ion layer and a thin disk of hydrogen, is investigated with three-dimensional particle-in-cell simulations in the case of oblique…

Plasma Physics · Physics 2008-11-26 T. Morita , T. Zh. Esirkepov , S. V. Bulanov , J. Koga , M. Yamagiwa

Proton Computed Tomography (pCT) provides a promising solution to enhance the accuracy of Relative Stopping Power (RSP) required for proton therapy planning. This research introduces a novel high-granularity pCT architecture that…

Uncertainties in the proton range in tissue during proton therapy limit the precision in treatment delivery. These uncertainties result in expanded treatment margins, thereby increasing radiation dose to healthy tissue. Real-time range…

Medical Physics · Physics 2018-10-17 Kristian Smeland Ytre-Hauge , Kyrre Skjerdal , John Mattingly , Ilker Meric

Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…

Medical Physics · Physics 2023-04-13 Sylvain Deffet , Edmond Sterpin

A prototype plastic scintillating fibre based beam profile monitor was tested at the Heidelberg Ion Therapy Centre / \textit{Heidelberg Ionenstrahl Therapiezentrum} (HIT) in 2016 to determine its beam property reconstruction performance and…

Instrumentation and Detectors · Physics 2018-06-27 B. D. Leverington , M. Dziewiecki , L. Renner , R. Runze

We demonstrate a scheme for enhanced proton acceleration from near-critical-density targets by splitting a laser pulse into a linearly and a circularly polarized laser pulse. The combination of two laser pulses generates a shock wave as…

Plasma Physics · Physics 2025-02-25 D N Gupta , Saurabh Kumar , S Kar

Proton radiography is used for advanced hydrotesting as a new type radiography technology due to its powerful penetration capability and high detection efficiency. A new proton radiography terminal will be developed to radiograph static…

Accelerator Physics · Physics 2015-01-28 Yan Yan , Li-Na Sheng , Zhi-Wu Huang , Jie Wang , Ze-En Yao , Jun-Run Wang , Zheng Wei , Jian-Cheng Yang , You-Jin Yuan
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