Related papers: Status and development of the TOP-IMPLART Project
During the past decade, the interaction of high-intensity lasers with solid targets has attracted much interest, regarding its potential in accelerating charged particles. In spite of tremendous progress in laser-plasma based acceleration,…
HollandPTC is an independent outpatient center for proton therapy, scientific research, and education. Patients with different types of cancer are treated with Intensity Modulated Proton Therapy (IMPT). In addition, the HollandPTC R&D…
Using three-dimensional particle-in-cell simulations, we further investigate the electron and ion acceleration from femtosecond laser-plasma peeler scheme which was proposed in our recent paper (Shen et al 2021 Phys. Rev. X 11 041002). In…
Proton acceleration by using a 620-TW, 18-J laser pulse of peak intensity of $5\times 10^{21}$ W/cm$^{2}$ irradiating a disk target is examined using three-dimensional particle-in-cell simulations. It is shown that protons are accelerated…
Intensity-modulated proton therapy (IMPT) offers superior dose conformity with reduced exposure to surrounding healthy tissues compared to conventional photon therapy. Improving IMPT delivery efficiency reduces motion-related uncertainties,…
Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments is still a matter of research. A possible technique exploits the information…
Proton therapy provides superior dose conformity compared with photon radiotherapy, concentrating radiation within the tumor while sparing adjacent healthy tissue. This advantage has been most effectively realized for static tumors in…
We experimentally demonstrate a notably enhanced acceleration of protons to high energy by relatively modest ultrashort laser pulses and structured dynamical plasma targets. Realized by special deposition of snow targets on sapphire…
Purpose:The recently proposed IPO-IMPT framework allows simultaneous optimization of dose, dose rate, and LET for FLASH treatment planning. Finding solutions to IPO-IMPT is difficult due to computational intensiveness. Nevertheless, an…
We report on the experimental studies of laser driven ion acceleration from double-layer target where a near-critical density target with a few-micron thickness is coated in front of a nanometer thin diamond-like carbon foil. A significant…
We present a nitrogen-targeting-Proton-Carbon-Alpha-Therapy method, abbreviated as Proton-CAT, which partially converts protons into carbon-12 and $\alpha$ particles through nuclear reactions between protons and nitrogen-15. Monte Carlo…
The interaction of micro- and nano-structured target surfaces with high-power laser pulses is being widely investigated for its unprecedented absorption efficiency. We have developed vertically aligned metallic micro-pillar arrays for…
Background and purpose: Accelerator-Based Boron Neutron Capture Therapy is a radiotherapy based on compact accelerator neutron sources requiring an epithermal neutron field for tumour irradiations. Neutrons of 10 keV are considered as the…
The design, construction, and preliminary testing of a second generation proton CT scanner is presented. All current treatment planning systems at proton therapy centers use X-ray CT as the primary imaging modality for treatment planning to…
A regime of multi-cascade proton acceleration in the interaction of $10^{21}-10^{22}$ W/cm$^2$ laser pulse with a structured target is proposed. The regime is based on the electron charge displacement under the action of laser ponderomotive…
In oncology, treating cancer with a beam of photons is a well established therapeutic technique, developed over 100 years, and today over 50% of cancer patients will undergo traditional X-ray radiotherapy. However, ionizing radiation…
Fermilab carries out an extensive program of accelerator-based high energy particle physics research at the Intensity Frontier that relies on the operation of 8 GeV and 120 GeV proton beamlines for a number of fixed target experiments.…
Computer tomography is one of the most promising new methods to image abnormal tissues inside the human body. Tomography is also used to position the patient accurately before radiation therapy. Hadron therapy for treating cancer has become…
The HICAT project is a Heavy Ion accelerator for light ion Cancer Treatment to be built for the clinics in Heidelberg, Germany. It consists of a 7 MeV/u linac, a compact synchrotron and three treatment places, one of them equipped with a…
Laser accelerated protons can be a complimentary source for treatment of oncological diseases to the existing hadron therapy facilities. We demonstrate how the protons, accelerated from near-critical density plasmas by laser pulses having…