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The increasing prevalence and growing size of data in modern applications have led to high costs for computation in traditional processor-centric computing systems. Moving large volumes of data between memory devices (e.g., DRAM) and…

Hardware Architecture · Computer Science 2022-06-01 Geraldo F. Oliveira , Juan Gómez-Luna , Saugata Ghose , Onur Mutlu

A range of computational biology software (GROMACS, AMBER, NAMD, LAMMPS, OpenMM, Psi4 and RELION) was benchmarked on a representative selection of HPC hardware, including AMD EPYC 7742 CPU nodes, NVIDIA V100 and AMD MI250X GPU nodes, and an…

The performance and efficiency of running large-scale datasets on traditional computing systems exhibit critical bottlenecks due to the existing "power wall" and "memory wall" problems. To resolve those problems, processing-in-memory (PIM)…

Hardware Architecture · Computer Science 2022-04-22 Yinglin Zhao , Jianlei Yang , Bing Li , Xingzhou Cheng , Xucheng Ye , Xueyan Wang , Xiaotao Jia , Zhaohao Wang , Youguang Zhang , Weisheng Zhao

Neural networks (NNs) are growing in importance and complexity. A neural network's performance (and energy efficiency) can be bound either by computation or memory resources. The processing-in-memory (PIM) paradigm, where computation is…

Hardware Architecture · Computer Science 2023-03-28 Geraldo F. Oliveira , Juan Gómez-Luna , Saugata Ghose , Amirali Boroumand , Onur Mutlu

Deep neural networks are widely deployed in many fields. Due to the in-situ computation (known as processing in memory) capacity of the Resistive Random Access Memory (ReRAM) crossbar, ReRAM-based accelerator shows potential in accelerating…

Hardware Architecture · Computer Science 2024-03-11 Chenguang Zhang , Zhihang Yuan , Xingchen Li , Guangyu Sun

Nanopore sequencing, superior to other sequencing technologies for DNA storage in multiple aspects, has recently attracted considerable attention. Its high error rates, however, demand thorough research on practical and efficient coding…

Information Theory · Computer Science 2024-06-21 Anisha Banerjee , Yonatan Yehezkeally , Antonia Wachter-Zeh , Eitan Yaakobi

The ever-increasing computation complexity of fastgrowing Deep Neural Networks (DNNs) has requested new computing paradigms to overcome the memory wall in conventional Von Neumann computing architectures. The emerging Computing-In-Memory…

Hardware Architecture · Computer Science 2021-12-14 Kaining Zhou , Yangshuo He , Rui Xiao , Jiayi Liu , Kejie Huang

The rapid advancement of Large Language Models (LLMs) has revolutionized various aspects of human life, yet their immense computational and energy demands pose significant challenges for efficient inference. The memory wall, the growing…

Hardware Architecture · Computer Science 2025-09-18 Hongyi Li , Songchen Ma , Huanyu Qu , Weihao Zhang , Jia Chen , Junfeng Lin , Fengbin Tu , Rong Zhao

Machine learning workflow development is a process of trial-and-error: developers iterate on workflows by testing out small modifications until the desired accuracy is achieved. Unfortunately, existing machine learning systems focus…

Databases · Computer Science 2018-12-17 Doris Xin , Stephen Macke , Litian Ma , Jialin Liu , Shuchen Song , Aditya Parameswaran

Transformers have become the backbone of neural network architecture for most machine learning applications. Their widespread use has resulted in multiple efforts on accelerating attention, the basic building block of transformers. This…

Hardware Architecture · Computer Science 2025-02-19 Dong Eun Kim , Tanvi Sharma , Kaushik Roy

Quantization has emerged to be an effective way to significantly boost the performance of deep neural networks (DNNs) by utilizing low-bit computations. Despite having lower numerical precision, quantized DNNs are able to reduce both memory…

Machine Learning · Computer Science 2019-11-15 Wenlei Bao , Li-Wen Chang , Yang Chen , Ke Deng , Amit Agarwal , Emad Barsoum , Abe Taha

The need to efficiently execute different Deep Neural Networks (DNNs) on the same computing platform, coupled with the requirement for easy scalability, makes Multi-Chip Module (MCM)-based accelerators a preferred design choice. Such an…

Hardware Architecture · Computer Science 2024-08-26 Abhijit Das , Enrico Russo , Maurizio Palesi

Database applications are increasingly bottlenecked by memory bandwidth and latency due to the memory wall and the limited scalability of DRAM. Join queries, central to analytical workloads, require intensive memory access and are…

Hardware Architecture · Computer Science 2025-08-13 Sabiha Tajdari , Anastasia Ailamaki , Sandhya Dwarkadas

The second-order training methods can converge much faster than first-order optimizers in DNN training. This is because the second-order training utilizes the inversion of the second-order information (SOI) matrix to find a more accurate…

Hardware Architecture · Computer Science 2022-10-28 Yilong Zhao , Li Jiang , Mingyu Gao , Naifeng Jing , Chengyang Gu , Qidong Tang , Fangxin Liu , Tao Yang , Xiaoyao Liang

Recently DRAM-based PIMs (processing-in-memories) with unmodified cell arrays have demonstrated impressive performance for accelerating AI applications. However, due to the very restrictive hardware constraints, PIM remains an accelerator…

Hardware Architecture · Computer Science 2023-10-17 Jaewoo Park , Sugil Lee , Jongeun Lee

Fully Homomorphic Encryption (FHE) is a technique that allows arbitrary computations to be performed on encrypted data without the need for decryption, making it ideal for securing many emerging applications. However, FHE computation is…

Processing in memory (PIM) moves computation into memories with the goal of improving throughput and energy-efficiency compared to traditional von Neumann-based architectures. Most existing PIM architectures are either general-purpose but…

Hardware Architecture · Computer Science 2019-07-23 Oscar Castañeda , Maria Bobbett , Alexandra Gallyas-Sanhueza , Christoph Studer

ReRAM-based accelerators exhibit enormous potential to increase computational efficiency for DNN inference tasks, delivering significant performance and energy savings over traditional platforms. By incorporating adaptive scheduling, these…

Hardware Architecture · Computer Science 2025-02-05 Mohammad Sabri , Marc Riera , Antonio Gonzalez

Approximate Nearest Neighbor Search (ANNS) is a core primitive in modern AI systems, and graph-based methods currently offer the best accuracy-efficiency trade-off at scale. The workload is fundamentally memory-bound: graph traversal…

Hardware Architecture · Computer Science 2026-05-26 Sitian Chen , Yusen Li , Yao Chen , Minwen Deng , Jintao Meng , Amelie Chi Zhou

Owing to its several merits over other DNA sequencing technologies, nanopore sequencers hold an immense potential to revolutionize the efficiency of DNA storage systems. However, their higher error rates necessitate further research to…

Information Theory · Computer Science 2024-05-08 Anisha Banerjee , Yonatan Yehezkeally , Antonia Wachter-Zeh , Eitan Yaakobi