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We propose a simple SIR model in order to investigate the impact of various confinement strategies on a most virulent epidemic. Our approach is motivated by the current COVID-19 pandemic. The main hypothesis is the existence of two…

Populations and Evolution · Quantitative Biology 2020-12-30 G. Nakamura , B. Grammaticos , M. Badoual

An SEIRS epidemic with disease fatalities is introduced in a growing population (modelled as a super-critical linear birth and death process). The study of the initial phase of the epidemic is stochastic, while the analysis of the major…

Populations and Evolution · Quantitative Biology 2017-03-29 Tom Britton , Désiré Ouédraogo

We investigate the long-time dynamics of a SIR epidemic model in the case of a population of pathogens infecting a homogeneous host population. The pathogen population is structured by a genotypic variable. When the initial mass of the…

Dynamical Systems · Mathematics 2023-06-05 Jean-Baptiste Burie , Arnaud Ducrot , Quentin Griette

Until a vaccine or therapy is found against the SARS-CoV-2 coronavirus, reaching herd immunity appears to be the only mid-term option. However, if the number of infected individuals decreases and eventually fades only beyond this threshold,…

Optimization and Control · Mathematics 2020-06-11 Pierre-Alexandre Bliman , Michel Duprez , Yannick Privat , Nicolas Vauchelet

The shape of an epidemic wave in simple epidemic models applies to a homogeneous distribution of infected people in the population. In large inhomogeneous systems, at country-scale for instance, the wave shape is similar except for the…

Chemical Physics · Physics 2022-11-21 L. Vanel

This paper presents a simple continuous-time linear vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

The adoption of prophylaxis attitudes, such as social isolation and use of face masks, to mitigate epidemic outbreaks strongly depends on the support of the population. In this work, we investigate a susceptible-infected-recovered (SIR)…

Physics and Society · Physics 2022-10-05 Diogo H. Silva , Celia Anteneodo , Silvio C. Ferreira

In this paper, we give a complete analysis of an SIS epidemiological model in a population of varying size with two dissimilar groups of infective individuals. It is mainly based on the discussion of the existence and stability of…

Classical Analysis and ODEs · Mathematics 2007-05-23 M. R. Razvan

Most epidemic models assume equal mixing among members of a population. An alternative approach is to model a population as random network in which individuals may have heterogeneous connectivity. This paper builds on previous research by…

Physics and Society · Physics 2007-05-23 Erik Volz

We study dynamics of a variant of the SIR the model, where we assume that individuals respond differently to dynamics of the epidemic. Their heterogeneous response is modeled by the Preisach hysteresis operator. The degree of heterogeneity…

Dynamical Systems · Mathematics 2021-03-16 Dmitrii Rachinskii , Samiha Rouf

Epidemics have shaped human history, often with devastating consequences, motivating the development of mathematical models to understand and control their dynamics. Among the many aspects of epidemic behavior, the conditions that lead to…

Populations and Evolution · Quantitative Biology 2026-05-01 Germano Hartmann Brill , Pablo Enrique Jurado Silvestrin , Sebastian Gonçalves

In this work we study the stability properties of the equilibrium points of deterministic epidemic models with nonconstant population size. Models with nonconstant population have been studied in the past only in particular cases, two of…

Optimization and Control · Mathematics 2022-02-25 Florin Avram , Rim Adenane , Lasko Basnarkov , Gianluca Bianchin , Dan Goreac , Andrei Halanay

Transportation networks play a critical part in the spread of infectious diseases between populations. In this work, we define a networked susceptible-exposed-infected-recovered epidemic process with loss of immunity over time (SEIRS) that…

Optimization and Control · Mathematics 2023-09-22 Brooks A. Butler , Raphael Stern , Philip E. Paré

The SIR model is a three-compartment model of the time development of an epidemic. After normalizing the dependent variables, the model is a system of two non-linear differential equations for the susceptible proportion $S$ and the infected…

Dynamical Systems · Mathematics 2021-04-27 William G. Faris

The expected number of secondary infections arising from each index case, referred to as the reproduction or $R$ number, is a vital summary statistic for understanding and managing epidemic diseases. There are many methods for estimating…

Applications · Statistics 2022-02-22 Joe Meagher , Nial Friel

We study Susceptible-Exposed-Asymptomatic-Infectious-Recovered (SEAIR) epidemic spreading model of COVID-19. It captures two important characteristics of the infectiousness of COVID-19: delayed start and its appearance before onset of…

Physics and Society · Physics 2021-02-03 Lasko Basnarkov

We investigate the long-time dynamics of a SIR epidemic model with infinitely many pathogen variants infecting a homogeneous host population. We show that the basic reproduction number $\mathcal{R}_0$ of the pathogen can be defined in that…

Populations and Evolution · Quantitative Biology 2023-05-11 Jean-Baptiste Burie , Arnaud Ducrot , Quentin Griette

An interesting inference drawn by some Covid-19 epidemiological models is that there exists a proportion of the population who are not susceptible to infection -- even at the start of the current pandemic. This paper introduces a model of…

Quantitative Methods · Quantitative Biology 2020-09-18 Thomas Parr , Anjali Bhat , Peter Zeidman , Aimee Goel , Alexander J. Billig , Rosalyn Moran , Karl J. Friston

Case isolation, that is, detection and isolation of infected individuals in order to prevent spread, is a strategy to curb infectious disease epidemics. Here, we study the efficiency of a case isolation strategy subject to time delays in…

Optimization and Control · Mathematics 2022-09-20 Jonas Hansson , Alain Govaert , Richard Pates , Emma Tegling , Kristian Soltesz

For a susceptible-infectious-susceptible (SIS) infection model in a heterogeneous population, we present simple formulae giving the leading-order asymptotic (large population) behaviour of the mean persistence time, from an endemic state to…

Probability · Mathematics 2017-07-12 Damian Clancy
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