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This paper presents a vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population amounts as a refrain for…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

We present a unified mathematical approach to epidemiological models with parametric heterogeneity, i.e., to the models that describe individuals in the population as having specific parameter (trait) values that vary from one individuals…

Populations and Evolution · Quantitative Biology 2012-02-14 Artem S. Novozhilov

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

Populations and Evolution · Quantitative Biology 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

We consider an epidemiological SIR model with an infection rate depending on the recovered population. We establish sufficient conditions for existence, uniqueness, and stability (local and global) of endemic equilibria and consider also…

Classical Analysis and ODEs · Mathematics 2021-07-09 Andres David Báez-Sánchez , Nara Bobko

Infection can spread easily on networks with heterogeneous degree distribution. Here, we considered targeted immunization on such networks, wherein a fraction of individuals with the highest connectivity are immunized. To quantify the…

Physics and Society · Physics 2021-11-05 Satoru Morita

COVID-19 will be a continuous threat to human population despite having a few vaccines at hand until we reach the endemic state through natural herd immunity and total immunization through universal vaccination. However, the vaccine acts as…

Populations and Evolution · Quantitative Biology 2022-08-26 V. R. Saiprasad , R. Gopal , V. K. Chandrasekar , M. Lakshmanan

When a fraction of a population becomes immune to an infectious disease, the population-wide infection risk decreases nonlinearly due to collective protection, known as herd immunity. Some studies based on mean-field models suggest that…

Physics and Society · Physics 2025-09-03 Takayuki Hiraoka , Zahra Ghadiri , Abbas K. Rizi , Mikko Kivelä , Jari Saramäki

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

Applications · Statistics 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

Recent evidences show that individuals who recovered from COVID-19 can be reinfected. However, this phenomenon has rarely been studied using mathematical models. In this paper, we propose a SEIRE epidemic model to describe the spread of the…

Populations and Evolution · Quantitative Biology 2022-05-17 Shaoli Wang , Tengfei Wang , Ya-nen Qi , Fei Xu

Metapopulation epidemic models describe epidemic dynamics in networks of spatially distant patches connected with pathways for migration of individuals. In the present study, we deal with a susceptible-infected-recovered (SIR)…

Physics and Society · Physics 2019-08-22 Akari Matsuki , Gouhei Tanaka

The Susceptible-Infected-Recovered (SIR) model has successfully mimicked the propagation of such airborne diseases as influenza A (H1N1). Although the SIR model has recently been studied in a multilayer networks configuration, in almost all…

Physics and Society · Physics 2015-07-16 L. G. Alvarez Zuzek , H. E. Stanley , L. A. Braunstein

An SIR model with the coinfection of the two infectious agents in a single host population is considered. The model includes the environmental carry capacity in each class of population. A special case of this model is analyzed and several…

Dynamical Systems · Mathematics 2019-05-14 Samia Ghersheen , Vladimir Kozlov , Vladimir G. Tkachev , Uno Wennergren

In this paper we generalise a simple discrete time stochastic SIR type model defined by Tuckwell and Williams. The SIR model by Tuckwell and Williams assumes a homogeneous population, a fixed infectious period, and a strict transition from…

Populations and Evolution · Quantitative Biology 2025-04-21 Carles Rovira

We present a detailed set-based analysis of the well-known SIR and SEIR epidemic models subjected to hard caps on the proportion of infective individuals, and bounds on the allowable intervention strategies, such as social distancing,…

Optimization and Control · Mathematics 2021-11-17 Willem Esterhuizen , Jean Lévine , Stefan Streif

When the body gets infected by a pathogen the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery the host might become susceptible again. Exposure to the pathogen in the environment…

Dynamical Systems · Mathematics 2014-11-13 Maria Vittoria Barbarossa , Gergely Röst

This paper is concerned with SIR (susceptible $\to$ infected $\to$ removed) household epidemic models in which the infection response may be either mild or severe, with the type of response also affecting the infectiousness of an…

Probability · Mathematics 2010-05-26 Frank Ball , Tom Britton , David Sirl

The current COVID-19 pandemic and subsequent lockdowns have highlighted the close and delicate relationship between a country's public health and economic health. Macroeconomic models that use preexisting epidemic models to calculate the…

Physics and Society · Physics 2020-07-01 Erhan Bayraktar , Asaf Cohen , April Nellis

We study the dynamics of epidemic and reaction-diffusion processes in metapopulation models with heterogeneous connectivity pattern. In SIR-like processes, along with the standard local epidemic threshold, the system exhibits a global…

Physics and Society · Physics 2009-11-13 Vittoria Colizza , Alessandro Vespignani

The SIR model with spatially inhomogeneous infection rate is studied with numerical simulations in one, two, and three dimensions, considering the case that the infection spreads inhomogeneously in densely populated regions or hot spots. We…

Medical Physics · Physics 2020-12-25 Hidetsugu Sakaguchi , Yuta Nakao

We investigate the spread of diseases, computer viruses or information on complex networks and also immunization strategies to prevent or control the spread. When an entire population cannot be immunized and the effect of immunization is…

Physics and Society · Physics 2011-04-14 Shinji Tanimoto