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We consider in this paper a general SEIRS model describing the dynamics of an infectious disease including latency, waning immunity and infection-induced mortality. We derive an infinite system of differential equations that provides an…

Optimization and Control · Mathematics 2022-01-26 Marcel Fang , Pierre-Alexandre Bliman

Since the turn of the millennium, computational modelling of biological systems has evolved remarkably and sees matured use spanning basic and clinical research. While the topic of the peri-millennial debate about the virtues and…

Quantitative Methods · Quantitative Biology 2025-08-05 Axel Loewe , Peter J. Hunter , Peter Kohl

This paper is concerned with the uniqueness, existence, comparison principle and long-time behavior of solutions to the initial-boundary value problem for a unidirectional diffusion equation. The unidirectional evolution often appears in…

Analysis of PDEs · Mathematics 2015-01-07 Goro Akagi , Masato Kimura

Existence and uniqueness of mass-conserving classical solutions to the continuous coagulation equation with collisional breakage are investigated for an unbounded class of collision kernels and a particular case of the distribution…

Analysis of PDEs · Mathematics 2018-08-23 Prasanta Kumar Barik , Ankik Kumar Giri

The aim of this note is to give a new proof to the conjecture, proposed by Gray et al. (2011), on the extinction of a stochastic differential equation SIS epidemic model. The conjecture was proved by Xu (2017). Our proof is much more direct…

Analysis of PDEs · Mathematics 2019-04-17 Wenshu Zhou , Xu Zhao , Xiaodan Wei

Exact solution of the Susceptible-Infectious-Recovered (SIR) epidemic model is derived, and various properties of solution are obtained directly from the exact solution. It is shown that there exists an exact solution of an initial value…

Populations and Evolution · Quantitative Biology 2022-10-04 Norio Yoshida

We try to justify rigorously, using a Wong-Zakai approximation argument, the susceptible-infected-susceptible (SIS) stochastic differential equation proposed in [2]. We discover that according to this approach the "right" stochastic model…

Probability · Mathematics 2021-02-17 Enrico Bernardi , Alberto Lanconelli

A punctuated equilibrium model of biological evolution with relative fitness between different species being the fundamental driving force of evolution is introduced. Mutation is modeled as a fitness updating cellular automaton process…

Condensed Matter · Physics 2015-06-25 H. F. Chau , L. Mak , P. K. Kwok

We consider a dislocation-based rate-independent model of single crystal gradient plasticity with isotropic or linear kinematic hardening. The model is weakly formulated through the so-called primal form of the flow rule as a variational…

Analysis of PDEs · Mathematics 2016-09-19 Francois Ebobisse , Patrizio Neff , Elias C. Aifantis

A novel model of biological organisms is advanced, treating an organism as a self-consistent system subject to a pathogen flux. The principal novelty of the model is that it describes not some parts, but a biological organism as a whole.…

Biological Physics · Physics 2015-05-13 V. I. Yukalov , D. Sornette , E. P. Yukalova , J. -Y. Henry , J. P. Cobb

We analyse the model of Tuberculosis due to Blower (Nature Medecine 1(8) 815-821) from the point of view of symmetry and singularity analysis. From the study we provide a demonstration of the integrability of the model to present an…

Quantitative Methods · Quantitative Biology 2014-07-18 Maba B. Matadi , Kesh S. Govinder

A Stokes-type problem for a viscoelastic model of salt rocks is considered, and existence, uniqueness and regularity are investigated in the scale of $L^2$-based Sobolev spaces. The system is transformed into a generalized Stokes problem,…

Analysis of PDEs · Mathematics 2017-01-27 R. A. Cipolatti , I. -S. Liu , L. A. Palermo , M. A. Rincon , R. M. S. Rosa

We study a mathematical model of a blood circulation network which is a generalization of the coronary model proposed by Smith, Pullan and Hunter. We prove the existence and uniqueness of the solution to the initial-boundary value problem…

Dynamical Systems · Mathematics 2007-05-23 Weihua Ruan , M. E. Clark , Meide Zhao , Anthony Curcio

In this paper we study a mathematical model for an infectious disease such as Cholera without life-time immunity. Due to the different mobility for susceptible, infected human and recovered human hosts, the diffusion coefficients are…

Analysis of PDEs · Mathematics 2020-11-18 Hong-Ming Yin

The qualitative analysis of the initial value problem P related to a non linear third order parabolic equation typical of diffusive models is discussed. Some basic properties of the the fundamental solution of a related linear operator are…

Mathematical Physics · Physics 2012-03-13 M. De Angelis , A. Maio , E. Mazziotti

In this article, we use the illness-death model to present a mathematical framework for studying the compression of morbidity (COM) hypothesis. It turns out that questions about COM are completely determined by the transition rates in the…

Quantitative Methods · Quantitative Biology 2018-07-31 Ralph Brinks

In this study, a new and natural way of constructing a stochastic Susceptible-Infected-Susceptible (SIS) model is proposed. This approach is natural in the sense that the disease transmission rate, $\beta$, is substituted with a generic,…

Probability · Mathematics 2025-11-07 Berk Tan Perçin

We consider a class of cross diffusion systems with degenerate (or porous media type) diffusion which is inspired by models in mathematical biology/ecology with zero self diffusions. Known techniques for scalar equations are no longer…

Analysis of PDEs · Mathematics 2019-09-12 Dung Le

We study a mathematical model describing the dynamics of dislocation densities in crystals. This model is expressed as a one-dimensional system of a parabolic equation and a first order Hamilton-Jacobi equation that are coupled together. We…

Analysis of PDEs · Mathematics 2007-05-23 Hassan Ibrahim

Inorganic scintillating crystals can be modelled as continua with microstructure. For rigid and isothermal crystals the evolution of charge carriers becomes in this way described by a reaction-diffusion-drift equation coupled with the…

Analysis of PDEs · Mathematics 2021-12-01 Fabrizio Davì