English

Stable States of Biological Organisms

Biological Physics 2015-05-13 v1 Medical Physics Cell Behavior

Abstract

A novel model of biological organisms is advanced, treating an organism as a self-consistent system subject to a pathogen flux. The principal novelty of the model is that it describes not some parts, but a biological organism as a whole. The organism is modeled by a five-dimensional dynamical system. The organism homeostasis is described by the evolution equations for five interacting components: healthy cells, ill cells, innate immune cells, specific immune cells, and pathogens. The stability analysis demonstrates that, in a wide domain of the parameter space, the system exhibits robust structural stability. There always exist four stable stationary solutions characterizing four qualitatively differing states of the organism: alive state, boundary state, critical state, and dead state.

Keywords

Cite

@article{arxiv.0907.4628,
  title  = {Stable States of Biological Organisms},
  author = {V. I. Yukalov and D. Sornette and E. P. Yukalova and J. -Y. Henry and J. P. Cobb},
  journal= {arXiv preprint arXiv:0907.4628},
  year   = {2015}
}

Comments

Latex file, 12 pages, 4 figures