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Patients with Frontotemporal Dementia (FTD) have impaired cognitive abilities, executive and behavioral traits, loss of language ability, and decreased memory capabilities. Based on the distinct patterns of cortical atrophy and symptoms,…

Artificial Intelligence · Computer Science 2021-04-13 Km Poonam , Rajlakshmi Guha , Partha P Chakrabarti

Fluctuations of the human heart beat constitute a complex system that has been studied mostly under resting conditions using conventional time series analysis methods. During physical exercise, the variability of the fluctuations is…

Data Analysis, Statistics and Probability · Physics 2020-08-13 Matti Molkkari , Giorgio Angelotti , Thorsten Emig , Esa Räsänen

Dementia is characterized by a decline in memory and thinking that is significant enough to impair function in activities of daily living. Patients seen in dementia specialty clinics are highly heterogeneous with a variety of different…

Machine Learning · Computer Science 2026-02-06 Sayantan Kumar , Zachary Abrams , Suzanne Schindler , Nupur Ghoshal , Philip Payne

Accelerometers produce enormous amounts of data. Research that incorporates such data often involves a derived summary metric to describe physical activity. Traditional metrics have often ignored the temporal nature of the data. We build on…

Agitation is a symptom that communicates distress in people living with dementia (PwD), and that can place them and others at risk. In a long term care (LTC) environment, care staff track and document these symptoms as a way to detect when…

Human activity recognition (HAR) ideally relies on data from wearable or environment-instrumented sensors sampled at regular intervals, enabling standard neural network models optimized for consistent time-series data as input. However,…

Signal Processing · Electrical Eng. & Systems 2025-01-28 Mengxi Liu , Daniel Geißler , Sizhen Bian , Bo Zhou , Paul Lukowicz

Computation of the instantaneous phase and amplitude via the Hilbert Transform is a powerful tool of data analysis. This approach finds many applications in various science and engineering branches but is not proper for causal estimation…

Neurons and Cognition · Quantitative Biology 2021-05-24 Michael Rosenblum , Arkady Pikovsky , Andrea A. Kühn , Johannes L. Busch

As the world population gets older, the healthcare system must be adapted, among others by providing continuous health monitoring at home and in the city. The social activities have a significant role in everyone health status. Hence, this…

Computers and Society · Computer Science 2016-12-01 Loïc Sevrin , Bertrand Massot , Norbert Noury , Nacer Abouchi , Fabrice Jumel , Jacques Saraydaryan

Heart rate variability (HRV) indices describe properties of interbeat intervals in electrocardiogram (ECG). Usually HRV is measured exclusively in normal sinus rhythm (NSR) excluding any form of paroxysmal rhythm. Atrial fibrillation (AF)…

Applications · Statistics 2023-08-28 Nikita Markov , Ilya Kotov , Konstantin Ushenin , Yakov Bozhko

Many studies of biomedical time series signals aim to measure the association between frequency-domain properties of time series and clinical and behavioral covariates. However, the time-varying dynamics of these associations are largely…

Methodology · Statistics 2016-10-05 Scott A. Bruce , Martica H. Hall , Daniel J. Buysse , Robert T. Krafty

Signal-to-noise ratio (SNR) statistics play a central role in many applications. A common situation where SNR is studied is when a continuous time signal is sampled at a fixed frequency with some noise in the background. While estimation…

Methodology · Statistics 2021-11-05 Francesco Giordano , Pietro Coretto

Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…

Signal Processing · Electrical Eng. & Systems 2024-11-28 Veronica Henao Isaza , David Aguillon , Carlos Andres Tobon Quintero , Francisco Lopera , John Fredy Ochoa Gomez

Timely detection of abrupt anomalies is crucial for real-time monitoring and security of modern systems producing high-dimensional data. With this goal, we propose effective and scalable algorithms. Proposed algorithms are nonparametric as…

Machine Learning · Computer Science 2020-02-19 Mehmet Necip Kurt , Yasin Yilmaz , Xiaodong Wang

In nonlinear dynamics, and to a lesser extent in other fields, a widely used measure of complexity is the Permutation Entropy. But there is still no known method to determine the accuracy of this measure. There has been little research on…

Methodology · Statistics 2017-11-22 Francisco Traversaro , Francisco Redelico

This work aimed, to determine the characteristics of activity series from fractal geometry concepts application, in addition to evaluate the possibility of identifying individuals with fibromyalgia. Activity level data were collected from…

Chaotic Dynamics · Physics 2018-09-28 Lucas Gabriel Souza França , Pedro Montoya , José Garcia Vivas Miranda

High-dimensional time series are characterized by a large number of measurements and complex dependence, and often involve abrupt change points. We propose a new procedure to detect change points in the mean of high-dimensional time series…

Methodology · Statistics 2019-03-19 Jun Li , Minya Xu , Ping-Shou Zhong , Lingjun Li

Objective: Exploit accelerometry data for an automatic, reliable, and prompt detection of spontaneous circulation during cardiac arrest, as this is both vital for patient survival and practically challenging. Methods: We developed a machine…

Signal Processing · Electrical Eng. & Systems 2023-02-13 Wolfgang J. Kern , Simon Orlob , Andreas Bohn , Wolfgang Toller , Jan Wnent , Jan-Thorsten Gräsner , Martin Holler

Despite the population of the noninvasive, economic, comfortable, and easy-to-install photoplethysmography (PPG), it is still lacking a mathematically rigorous and stable algorithm which is able to simultaneously extract from a…

Neurons and Cognition · Quantitative Biology 2017-09-05 Antonio Cicone , Hau-Tieng Wu

There has recently been growing evidence that atrial fibrillation (AF), the most common cardiac arrhythmia, is independently associated with the risk of dementia. This represents a very recent frontier with high social impact for the number…

Our work utilized a non-sequential simulation-based inference algorithm to provide an amortized neural density estimator, which approximates the posterior distribution for seven parameters of the adaptive exponential integrate-and-fire…

Neural and Evolutionary Computing · Computer Science 2026-02-13 Jakob Kaiser , Eric Müller , Johannes Schemmel