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Dementia disorders are increasingly becoming sources of a broad range of problems, strongly interfering with normal daily tasks of a growing number of individuals. Such neurodegenerative diseases are often accompanied with progressive brain…

Persistent homology (PH) is a recently developed theory in the field of algebraic topology to study shapes of datasets. It is an effective data analysis tool that is robust to noise and has been widely applied. We demonstrate a general…

Signal Processing · Electrical Eng. & Systems 2020-05-05 Yu-Min Chung , Chuan-Shen Hu , Yu-Lun Lo , Hau-Tieng Wu

Objective While Alzheimer's disease (AD) and frontotemporal dementia (FTD) show some common memory deficits, these two disorders show partially overlapping complex spatiotemporal patterns of neural dynamics. The objective of this study is…

Neurons and Cognition · Quantitative Biology 2025-07-14 Sungwoo Ahn , Evie A. Malaia , Leonid L Rubchinsky

This study proposes a method for radar-based identification of individuals using a combination of their respiratory and heartbeat features. In the proposed method, the target individual's respiratory features are extracted using the…

Signal Processing · Electrical Eng. & Systems 2024-12-18 Haruto Kobayashi , Yuji Tanaka , Takuya Sakamoto

Heart rate is an important vital sign used in the diagnosis of many medical conditions. Conventionally, heart rate is measured using a medical device such as pulse oxymeter. Physiological parameters such as heart rate bear a correlation to…

Audio and Speech Processing · Electrical Eng. & Systems 2020-02-27 Mohammed Usman , Zeeshan Ahmad , Mohd Wajid

Many trials are designed to collect outcomes at or around pre-specified times after randomization. If there is variability in the times when participants are actually assessed, this can pose a challenge to learning the effect of treatment,…

In many phenomena, data are collected on a large scale and of different frequencies. In this context, functional data analysis (FDA) has become an important statistical methodology for analyzing and modeling such data. The approach of FDA…

Methodology · Statistics 2022-04-11 Israel Martínez-Hernández , Marc G. Genton

We introduce a segmentation algorithm to probe temporal organization of heterogeneities in human heartbeat interval time series. We find that the lengths of segments with different local values of heart rates follow a power-law…

Today's fitness bands and smartwatches typically track heart rates (HR) using optical sensors. Large behavioral studies such as the UK Biobank use activity trackers without such optical sensors and thus lack HR data, which could reveal…

Quantitative Methods · Quantitative Biology 2024-11-04 Max Moebus , Lars Hauptmann , Nicolas Kopp , Berken Demirel , Björn Braun , Christian Holz

Patients at high risk for sudden death often exhibit complex heart rhythms in which abnormal heartbeats are interspersed with normal heartbeats. We analyze such a complex rhythm in a single patient over a 12-hour period and show that the…

Background. Alzheimer's disease and related dementia (ADRD) are characterized by multiple and progressive anatomo clinical changes. Yet, modeling changes over disease course from cohort data is challenging as the usual timescales are…

Deep learning models for atrial fibrillation (AF) detection are increasingly trained on heterogeneous electrocardiogram (ECG) datasets with varying sampling frequencies, yet the specific consequences of these discrepancies on model…

Healthcare datasets present many challenges to both machine learning and statistics as their data are typically heterogeneous, censored, high-dimensional and have missing information. Feature selection is often used to identify the…

Machine Learning · Computer Science 2022-07-06 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

An aggregated method of nonparametric estimators based on time-domain and state-domain estimators is proposed and studied. To attenuate the curse of dimensionality, we propose a factor modeling strategy. We first investigate the asymptotic…

Statistics Theory · Mathematics 2007-06-13 Jianqing Fan , Yingying Fan , Jinchi Lv

Dementia is a neurodegenerative disorder that has been growing among elder people over the past decades. This growth profoundly impacts the quality of life for patients and caregivers due to the symptoms arising from it. Agitation and…

Artificial Intelligence · Computer Science 2024-12-30 Abeer Badawi , Somayya Elmoghazy , Samira Choudhury , Khalid Elgazzar , Amer Burhan

Objective: We aimed to determine the relationship between day-to-day sleep efficiency variability and cognitive function among older adults using accelerometer data and three cognitive tests. Methods: Older adults aged 65+ with 5 days of…

Applications · Statistics 2023-11-07 Collin Sakal , Tingyou Li , Juan Li , Xinyue Li

We present the multiscale entropy analysis of short term physiological time series of simultaneously acquired samples of heart rate, blood pressure and lung volume, from healthy subjects and from subjects with Chronic Heart Failure.…

Medical Physics · Physics 2007-05-23 L. Angelini , R. Maestri , D. Marinazzo , L. Nitti , M. Pellicoro , G. D. Pinna , S. Stramaglia , S. A. Tupputi

PPG based heart rate (HR) monitoring has recently attracted much attention with the advent of wearable devices such as smart watches and smart bands. However, due to severe motion artifacts (MA) caused by wristband stumbles, PPG based HR…

Signal Processing · Electrical Eng. & Systems 2020-10-05 Mahmoud Essalat , Mahdi Boloursaz Mashhadi , Farokh Marvasti

Parkinsons Disease is a neurological disorder and prevalent in elderly people. Traditional ways to diagnose the disease rely on in-person subjective clinical evaluations on the quality of a set of activity tests. The high-resolution…

Machine Learning · Computer Science 2020-10-16 Weijian Li , Wei Zhu , E. Ray Dorsey , Jiebo Luo

Patients with sleep disorders can better manage their lifestyle if they know about their special situations. Detection of such sleep disorders is usually possible by analyzing a number of vital signals that have been collected from the…

Signal Processing · Electrical Eng. & Systems 2020-04-14 Mohamadreza Jafaryani , Saeed Khorram , Vahid Pourahmadi , Minoo Shahbazi