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This study explores the potential of Rhythm Formant Analysis (RFA) to capture long-term temporal modulations in dementia speech. Specifically, we introduce RFA-derived rhythm spectrograms as novel features for dementia classification and…

Accelerometers enable an objective measurement of physical activity levels among groups of individuals in free-living environments, providing high-resolution detail about physical activity changes at different time scales. Current…

Methodology · Statistics 2022-01-21 Marcos Matabuena , Alexander Petersen

Information from frequency bands in biomedical time series provides useful summaries of the observed signal. Many existing methods consider summaries of the time series obtained over a few well-known, pre-defined frequency bands of…

Methodology · Statistics 2023-01-11 Raanju R. Sundararajan , Scott A. Bruce

High Frequency Oscillations (HFOs), rapid bursts of brain activity above 80 Hz, have emerged as a highly specific biomarker for epileptogenic tissue. Recent evidence suggests that HFOs are also present in Alzheimer's Disease (AD),…

Signal Processing · Electrical Eng. & Systems 2026-01-13 Samin Yaser , Mahad Ali , Yang Jiang , Phuc Nguyen , Jing Xiang , Laura J. Brattain

Scaling analysis of heart rate time series has emerged as an useful tool for assessment of autonomic cardiac control. We investigate the heart rate time series of ten athletes (five males and five females), by applying detrended fluctuation…

Quantitative Methods · Quantitative Biology 2007-05-23 M Baumert , LM Brechtel , J Lock , A Voss , D Abbott

Detrend fluctuation analysis (DFA) has become a choice method for effective analysis of a broad variety of nonstationary signals. We show in the present article that, provided the nonstationary fluctuations occur at a large enough time…

Quantitative Methods · Quantitative Biology 2007-05-23 Luciano da Fontoura Costa , Ruth Caldeira de Melo , Ester da Silva , Audrey Borghi-Silva , Aparecida Maria Catai

Irregular multivariate time series with missing values present significant challenges for predictive modeling in domains such as healthcare. While deep learning approaches often focus on temporal interpolation or complex architectures to…

Machine Learning · Computer Science 2026-03-16 Dingyi Nie , Yixing Wu , C. -C. Jay Kuo

In the analysis of remote healthcare monitoring data, time series representation learning offers substantial value in uncovering deeper patterns of patient behavior, especially given the fine temporal granularity of the data. In this study,…

Artificial Intelligence · Computer Science 2025-02-17 Jin Cui , Alexander Capstick , Payam Barnaghi , Gregory Scott

We study the Heart Rate Variability (HRV) using scale specific variance and scaling exponents as measures of healthy and cardiac impaired individuals. Our results show that the variance and the scaling exponent are uncorrelated. We find…

Agitation is one of the most common responsive behaviors in people living with dementia, particularly among those residing in community settings without continuous clinical supervision. Timely prediction of agitation can enable early…

Signal Processing · Electrical Eng. & Systems 2025-06-10 Ali Abedi , Charlene H. Chu , Shehroz S. Khan

Multiresolution Wavelet Transform and Detrended Fluctuation Analysis have been recently proven as excellent methods in the analysis of Heart Rate Variability, and in distinguishing between healthy subjects and patients with various…

Objective: The circadian rhythm synchronizes physiological and behavioural patterns with the 24-hour light-dark cycle. Disruption to the circadian rhythm is linked to various health conditions, though optimal methods to describe these…

Analyzing time series in the frequency domain enables the development of powerful tools for investigating the second-order characteristics of multivariate processes. Parameters like the spectral density matrix and its inverse, the coherence…

Methodology · Statistics 2024-01-19 Jonas Krampe , Efstathios Paparoditis

This article introduces a nonparametric approach to spectral analysis of a high-dimensional multivariate nonstationary time series. The procedure is based on a novel frequency-domain factor model that provides a flexible yet parsimonious…

Methodology · Statistics 2019-10-29 Zeda Li , Ori Rosen , Fabio Ferrarelli , Robert T. Krafty

Traditional echocardiographic parameters such as ejection fraction (EF) and global longitudinal strain (GLS) have limitations in the early detection of cardiac dysfunction. EF often remains normal despite underlying pathology, and GLS is…

Machine Learning · Computer Science 2025-07-21 Beka Begiashvili , Carlos J. Fernandez-Candel , Matías Pérez Paredes

We consider the use of a running measure of power spectrum disorder to distinguish between the normal sinus rhythm of the heart and two forms of cardiac arrhythmia: atrial fibrillation and atrial flutter. This spectral entropy measure is…

Quantitative Methods · Quantitative Biology 2009-02-16 Phillip P. A. Staniczenko , Chiu Fan Lee , Nick S. Jones

Interpreting the environmental, behavioural and psychological data from in-home sensory observations and measurements can provide valuable insights into the health and well-being of individuals. Presents of neuropsychiatric and…

Signal Processing · Electrical Eng. & Systems 2021-05-24 Roonak Rezvani , Samaneh Kouchaki , Ramin Nilforooshan , David J. Sharp , Payam Barnaghi

Here we discuss a new fast detrending method for the non-stationary RR time series used in Heart Rate Variability analysis. The described method is based on the diffusion equation, and we show numerically that it is equivalent to the widely…

Data Analysis, Statistics and Probability · Physics 2020-02-18 M. Andrecut

Time series from different regions of interest (ROI) of default mode network (DMN) from Functional Magnetic Resonance Imaging (fMRI) can reveal significant differences between healthy and unhealthy people. Here, we propose the utility of an…

Machine Learning · Computer Science 2024-07-30 Sneha Noble , Chakka Sai Pradeep , Neelam Sinha , Thomas Gregor Issac

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk
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