Related papers: Strong well-posedness and inverse identification p…
Cancer cell mutations occur when cells undergo multiple cell divisions, and these mutations can be spontaneous or environmentally-induced. The mechanisms that promote and sustain these mutations are still not fully understood. This study…
This article is devoted to forward and inverse problems associated with time-independent semilinear nonlocal wave equations. We first establish comprehensive well-posedness results for some semilinear nonlocal wave equations. The main…
Solving equilibrium problems under constraints is an important problem in optimization and optimal control. In this context an important practical challenge is the efficient incorporation of constraints. We develop a continuous-time method…
We study the existence of weak solutions to a Cahn--Hilliard--Darcy system coupled with a convection-reaction-diffusion equation through the fluxes, through the source terms and in Darcy's law. The system of equations arises from a mixture…
We consider a convective bulk-surface Cahn--Hilliard system with dynamic boundary conditions and singular potentials. For this model, well-posedness results concerning weak and strong solutions have already been established in the…
In this paper, we study a phase field model for a tumor growth model of Cahn--Hilliard type in which the often assumed parabolic relaxation of the chemical potential is replaced by a hyperbolic one. We show that the resulting…
The Cahn--Hilliard equation is one of the most common models to describe phase segregation processes in binary mixtures. In recent times, various dynamic boundary conditions have been introduced to model interactions of the materials with…
In this paper, we use the Bayesian inversion approach to study the data assimilation problem for a family of tumor growth models described by porous-medium type equations. The models contain uncertain parameters and are indexed by a…
We consider the problem of minimizing the sum of a convex function and a convex function composed with an injective linear mapping. For such problems, subject to a coercivity condition at fixed points of the corresponding Picard iteration,…
We consider the classical initial and boundary value problem for the Cahn--Hilliard equation with non-degenerate mobility and singular (e.g., logarithmic) potential. We prove that any weak solution converges to a single equilibrium using…
Proximal splitting algorithms for monotone inclusions (and convex optimization problems) in Hilbert spaces share the common feature to guarantee for the generated sequences in general weak convergence to a solution. In order to achieve…
Mathematical models that describe the tumor growth process have been formulated by several authors in order to understand how cancer develops and to develop new treatment approaches. In this study, it is aimed to investigate the long-time…
We study a nonlocal adhesion model for two interacting tumor cell phenotypes, combining diffusion, pairwise interactions, and random phenotypic switching. The system admits a microscopic diffusion--jump particle description whose mean-field…
We study weighted Tikhonov regularization for large-scale linear discrete ill-posed problems with random noise. Under a polynomial upper-bound assumption on the generalized eigenvalues of the discrete forward operator, we derive stochastic…
We present a novel approach to nonlinear constrained Tikhonov regularization from the viewpoint of optimization theory. A second-order sufficient optimality condition is suggested as a nonlinearity condition to handle the nonlinearity of…
Development of resistance limits efficiency of present anticancer therapies and preventing it remains big challenge in cancer research. It is accepted, at intuitive level, that the resistance emerges as a consequence of cancer cells…
A nonlocal Cahn-Hilliard model with a nonsmooth potential of double-well obstacle type that promotes sharp interfaces in the solution is presented. To capture long-range interactions between particles, a nonlocal Ginzburg-Landau energy…
Here we consider the nonlocal Cahn-Hilliard equation with constant mobility in a bounded domain. We prove that the associated dynamical system has an exponential attractor, provided that the potential is regular. In order to do that a…
The Cahn-Hilliard equation is a widely used model for describing phase separation processes in a binary mixture. In this paper, we investigate the viscous Cahn-Hilliard equation with a degenerate, phase-dependent mobility. We define the…
We consider the problem of establishing nonlinear smoothing as a general feature of nonlinear dispersive equations, i.e. the improved regularity of the integral term in Duhamel's formula, with respect to the initial data and the…