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We present a new approach to convexification of the Tikhonov regularization using a continuation method strategy. We embed the original minimization problem into a one-parameter family of minimization problems. Both the penalty term and the…

Numerical Analysis · Mathematics 2015-06-15 Valdemar Melicher , Vladimir Vrabel

We consider a general class of bulk-surface convective Cahn--Hilliard systems with dynamic boundary conditions. In contrast to classical Neumann boundary conditions, the dynamic boundary conditions of Cahn--Hilliard type allow for dynamic…

Analysis of PDEs · Mathematics 2024-07-23 Patrik Knopf , Jonas Stange

We analyze nonlinear degenerate coupled PDE-PDE and PDE-ODE systems that arise, for example, in the modelling of biofilm growth. One of the equations, describing the evolution of a biomass density, exhibits degenerate and singular…

Analysis of PDEs · Mathematics 2023-04-04 Koondanibha Mitra , Stefanie Sonner

We consider a modified Tikhonov-type functional for the solution of ill-posed nonlinear inverse problems. Motivated by applications in the field of production engineering, we allow small deviations in the solution, which are modeled through…

Numerical Analysis · Mathematics 2020-07-14 Iwona Piotrowska-Kurczewski , Georgia Sfakianaki

In this work, we develop a structure-preserving numerical scheme for a Cahn-Hilliard-Darcy model that describes tumor growth in a fluid-saturated porous medium. First, we derive a physically consistent model from the general framework…

Numerical Analysis · Mathematics 2026-05-22 Daniel Acosta-Soba , Francisco Guillén-González , J. Rafael Rodríguez-Galván

From the viewpoint of inverse problem, the optimization of drug release based on the multi-laminated drug controlled release devices has been regarded as the solution problem of the diffusion equation initial value inverse problem. In view…

Numerical Analysis · Mathematics 2019-04-15 Xinming Zhang , Ling Ma

We study the inverse optimal transport problem of recovering the ground cost from an optimal transport plan. In discrete settings, this problem reduces to inverse linear programming and is intrinsically ill-posed, exhibiting…

Optimization and Control · Mathematics 2026-04-27 Gabriel Peyré , Clarice Poon , Oscar Tron

An ill-posed inverse problem of autoconvolution type is investigated. This inverse problem occurs in nonlinear optics in the context of ultrashort laser pulse characterization. The novelty of the mathematical model consists in a physically…

Mathematical Physics · Physics 2013-01-28 Daniel Gerth , Bernd Hofmann , Simon Birkholz , Sebastian Koke , Günter Steinmeyer

We find analytical solutions to the Cahn-Hilliard equation for the dynamics of an interface in a system with a conserved order parameter (Model B). We show that, although steady-state solutions of Model B are unphysical in the far-field,…

Soft Condensed Matter · Physics 2009-10-30 R. M. L. Evans , M. E. Cates

There has been recently an important interest in deriving rigorously the Cahn-Hilliard equation from the nonlocal equation, also called aggregation equation. So far, only non-degenerate mobilities were treated. Since we are motivated by…

Analysis of PDEs · Mathematics 2022-12-19 Charles Elbar , Jakub Skrzeczkowski

Local well-posedness for the two-dimensional Zakharov-Kuznetsov equation in the fully periodic case with initial data in Sobolev spaces $H^s$, $s>1$, is proved. Frequency dependent time localization is utilized to control the derivative…

Analysis of PDEs · Mathematics 2021-06-17 Shinya Kinoshita , Robert Schippa

We study some properties of a multi-species degenerate Ginzburg-Landau energy and its relation to a cross-diffusion Cahn-Hilliard system. The model is motivated by multicomponent mixtures where crossdiffusion effects between the different…

Analysis of PDEs · Mathematics 2024-08-08 Jean Cauvin-Vila , Virginie Ehrlacher , Greta Marino , Jan-Frederik Pietschmann

We derive a Cahn-Hilliard-Darcy model to describe multiphase tumour growth taking interactions with multiple chemical species into account as well as the simultaneous occurrence of proliferating, quiescent and necrotic regions. Via a…

Analysis of PDEs · Mathematics 2019-11-01 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Emanuel Sitka

We provide a new version of the Tikhonov theorem for both two-scale forward systems and also two-scale forward-backward systems of stochastic differential equations, which also covers the McKean-Vlasov case. Differently from what is usually…

Probability · Mathematics 2024-03-26 Matteo Burzoni , Alekos Cecchin , Andrea Cosso

Using basic thermodynamic principles we derive a Cahn--Hilliard--Darcy model for tumour growth including nutrient diffusion, chemotaxis, active transport, adhesion, apoptosis and proliferation. The model generalises earlier models and in…

Analysis of PDEs · Mathematics 2016-06-06 Harald Garcke , Kei Fong Lam , Emanuel Sitka , Vanessa Styles

A reaction-diffusion equation with power nonlinearity formulated either on the half-line or on the finite interval with nonzero boundary conditions is shown to be locally well-posed in the sense of Hadamard for data in Sobolev spaces. The…

Analysis of PDEs · Mathematics 2018-10-15 A. Alexandrou Himonas , Dionyssios Mantzavinos , Fangchi Yan

We study an initial-boundary value problem (IBVP) for a coupled Cahn-Hilliard-Hele-Shaw system that models tumor growth. For large initial data with finite energy, we prove global (local resp.) existence, uniqueness, higher order spatial…

Analysis of PDEs · Mathematics 2012-05-31 John Lowengrub , Edriss S. Titi , Kun Zhao

We investigate the dynamics of a nonlinear system modeling tumor growth with drug application. The tumor is viewed as a mixture consisting of proliferating, quiescent and dead cells as well as a nutrient in the presence of a drug. The…

Analysis of PDEs · Mathematics 2015-06-22 Donatella Donatelli , Konstantina Trivisa

We consider a one dimensional periodic forward-backward parabolic equation, regularized by a non-linear fourth order term of order $\epsilon^2\ll 1$. This equation is known in the literature as Cahn-Hilliard equation with degenerate…

Analysis of PDEs · Mathematics 2015-10-20 Matias G. Delgadino

We propose regularization schemes for deformable registration and efficient algorithms for their numerical approximation. We treat image registration as a variational optimal control problem. The deformation map is parametrized by its…

Optimization and Control · Mathematics 2016-09-09 Andreas Mang , George Biros