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This article is concerned with the inverse problem on determining the temporal component of the source term in a coupled system of time-fractional diffusion equations by single point observation. Under a non-degeneracy condition on the…

Analysis of PDEs · Mathematics 2026-03-13 Mohamed BenSalah , Yikan Liu

This paper introduces a method for estimating the shape and location of an embedded tumor. The approach utilizes shape optimization techniques, applying the coupled complex boundary method. By rewriting the problem -- characterized by a…

Numerical Analysis · Mathematics 2025-05-30 Julius Fergy Tiongson Rabago

This paper concerns a Fokker-Planck equation on the positive real line modeling nucleation and growth of clusters. The main feature of the equation is the dependence of the driving vector field and boundary condition on a non-local order…

Analysis of PDEs · Mathematics 2020-06-04 Joseph G. Conlon , André Schlichting

The Functionalized Cahn-Hilliard equation has been proposed as a model for the interfacial energy of phase-separated mixtures of amphiphilic molecules. We study the existence of a nonnegative weak solutions of a gradient flow of the…

Analysis of PDEs · Mathematics 2023-10-09 Shibin Dai , Qiang Liu , Toai Luong , Keith Promislow

We show well-posedness of a diffuse interface model for a two-phase flow of two viscous incompressible fluids with different densities locally in time. The model leads to an inhomogeneous Navier-Stokes/Cahn-Hilliard system with a solenoidal…

Analysis of PDEs · Mathematics 2020-10-14 Helmut Abels , Josef Weber

In this article, we are concerned with the analysis on the numerical reconstruction of the spatial component in the source term of a time-fractional diffusion equation. This ill-posed problem is solved through a stabilized nonlinear…

Numerical Analysis · Mathematics 2020-05-06 Daijun Jiang , Yikan Liu , Dongling Wang

We consider a phase-field model of prostate cancer growth with chemotherapy and antiangiogenic therapy effects which is introduced in [2]. It is comprised of phase-field equation to describe tumor growth, which is coupled to a…

Analysis of PDEs · Mathematics 2020-10-22 Tania Biswas , Elisabetta Rocca

This article is concerned with a gradient-flow approach to a Cahn-Hilliard model for viscoelastic phase separation introduced by Zhou et al. (Phys. Rev. E, 2006) in its variant with constant mobility. By means of time-incremental…

Analysis of PDEs · Mathematics 2025-08-22 Moritz Immanuel Gau , Katharina Hopf

This paper addresses the well-posedness of a general class of bulk-surface convective Cahn--Hilliard systems with singular potentials. For this model, we first prove the existence of a global-in-time weak solution by approximating the…

Analysis of PDEs · Mathematics 2025-05-15 Patrik Knopf , Jonas Stange

In a Hilbert space, we provide a fast dynamic approach to the hierarchical minimization problem which consists in finding the minimum norm solution of a convex minimization problem. For this, we study the convergence properties of the…

Optimization and Control · Mathematics 2021-08-21 Hedy Attouch , Aicha Balhag , Zaki Chbani , Hassan Riahi

The paper deals with a phase field system of Cahn-Hilliard type. For positive viscosity coefficients, the authors prove an existence and uniqueness result and study the long time behavior of the solution by assuming the nonlinearities to be…

Analysis of PDEs · Mathematics 2014-03-24 Pierluigi Colli , Gianni Gilardi , Danielle Hilhorst

In this paper we study the rigorous sharp interface limit of a diffuse interface model related to the dynamics of tumor growth, when a parameter $\epsilon$, representing the interface thickness between the tumorous and non tumorous cells,…

Analysis of PDEs · Mathematics 2016-12-21 E. Rocca , R. Scala

In this work, we present a phase-field model for tumour growth, where a diffuse interface separates a tumour from the surrounding host tissue. In our model, we consider transport processes by an internal, non-solenoidal velocity field. We…

Numerical Analysis · Mathematics 2024-06-21 Harald Garcke , Dennis Trautwein

This paper concerns multiphase models of tumor growth in interaction with a surrounding tissue, taking into account also the interplay with diffusible nutrients feeding the cells. Models specialize in nonlinear systems of possibly…

Mathematical Physics · Physics 2017-01-20 Andrea Tosin

We present a numerical scheme for solving an inverse problem for parameter estimation in tumor growth models for glioblastomas, a form of aggressive primary brain tumor. The growth model is a reaction-diffusion partial differential equation…

Medical Physics · Physics 2020-04-22 Shashank Subramanian , Klaudius Scheufele , Miriam Mehl , George Biros

We study the propagation of elastic waves in the time-harmonic regime in a waveguide which is unbounded in one direction and bounded in the two other (transverse) directions. We assume that the waveguide is thin in one of these transverse…

Analysis of PDEs · Mathematics 2025-10-13 Laurent Bourgeois , Lucas Chesnel , Sonia Fliss

We consider the initial-boundary value problem of a thermodynamically consistent diffuse interface model for incompressible two-phase flows with unmatched densities in a bounded domain $\Omega\subset\mathbb{R}^3$. Our first aim is to study…

Analysis of PDEs · Mathematics 2026-03-30 Harald Garcke , Maoyin Lv , Hao Wu

This paper deals with a general system of equations and conditions arising from a mathematical model of prostate cancer growth with chemotherapy and antiangiogenic therapy that has been recently introduced and analyzed (see [P. Colli et…

Analysis of PDEs · Mathematics 2021-04-02 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

In a Hilbert setting we aim to study a second order in time differential equation, combining viscous and Hessian-driven damping, containing a time scaling parameter function and a Tikhonov regularization term. The dynamical system is…

Optimization and Control · Mathematics 2024-04-24 Robert Ernö Csetnek , Mikhail A. Karapetyants

In this paper, we study an optimal control problem for a two-dimensional Cahn-Hilliard-Darcy system with mass sources that arises in the modeling of tumor growth. The aim is to monitor the tumor fraction in a finite time interval in such a…

Analysis of PDEs · Mathematics 2023-07-28 Juergen Sprekels , Hao Wu