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A design for a compact x-ray light source (CXLS) with flux and brilliance orders of magnitude beyond existing laboratory scale sources is presented. The source is based on inverse Compton scattering of a high brightness electron bunch on a…

We present a novel microlocal analysis of a non-linear ray transform, $\mathcal{R}$, arising in Compton Scattering Tomography (CST). Due to attenuation effects in CST, the integral weights depend on the reconstruction target, $f$, which has…

Functional Analysis · Mathematics 2025-09-19 James W. Webber , Sean Holman

We propose a novel technique of microscopy to overcome the effects of both scattering and limitation of the accessible depth due to the objective working distance. By combining Laser Optical Feedback Imaging (LOFI) with Acoustic Photon…

Optical coherence tomography (OCT) is a volumetric imaging modality that empowers clinicians and scientists to noninvasively visualize the cross-sections of biological samples. As the latest generation of its kind, Fourier-domain OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Yuye Ling , Mengyuan Wang , Yu Gan , Xinwen Yao , Leopold Schmetterer , Chuanqing Zhou , Yikai Su

The generation of X-rays and {\gamma}-rays based on synchrotron radiation from free electrons, emitted in magnet arrays such as undulators, forms the basis of much of modern X-ray science. This approach has the drawback of requiring very…

This paper aims to evaluate mid-infrared (MIR) Optical Coherence Tomography (OCT) systems as a tool to penetrate different materials and detect sub-surface irregularities. This is useful for monitoring production processes, allowing…

High-numerical-aperture optical coherence tomography (OCT) enables sub-cellular imaging but faces a trade-off between lateral resolution and depth of focus. Computational refocusing can correct defocus in Fourier-domain OCT, yet its…

Optics · Physics 2026-05-22 Yue Zhu , Shuichi Makita , Naoki Fukutake , Yoshiaki Yasuno

In numerous applications, Fourier-domain optical coherence tomography (FD-OCT) suffers from a limited imaging depth due to signal roll-off, a limited focal range, and autocorrelation noise. Here, we propose a parallel full-field FD-OCT…

Laser wakefield acceleration of electrons represents a basis for several types of novel X-ray sources based on Thomson scattering or betatron radiation. The latter provides a high photon flux and a small source size, both being…

Medical Physics · Physics 2018-12-26 J. Götzfried , A. Döpp , M. Gilljohann , H. Ding , S. Schindler , J. Wenz , L. Hehn , F. Pfeiffer , S. Karsch

Optical tomography has emerged as a non-invasive imaging method, providing three-dimensional insights into subcellular structures and thereby enabling a deeper understanding of cellular functions, interactions, and processes. Conventional…

Medical Physics · Physics 2023-12-14 Jiawei Sun , Bin Yang , Nektarios Koukourakis , Jochen Guck , Juergen W. Czarske

While micro-CT systems are instrumental in preclinical research, clinical micro-CT imaging has long been desired with cochlear implantation as a primary example. The structural details of the cochlear implant and the temporal bone require a…

The pests captured with imaging devices may be relatively small in size compared to the entire images, and complex backgrounds have colors and textures similar to those of the pests, which hinders accurate feature extraction and makes pest…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Ga-Eun Kim , Chang-Hwan Son

Optical tomographic cross-sectional images of biological samples were made possible by interferometric imaging techniques such as Optical Coherence Tomography (OCT). Owing to its unprecedented view of the sample, OCT has become a gold…

Medical Physics · Physics 2020-07-13 Pedro Mecê , Elena Gofas-Salas , Michel Paques , Kate Grieve , Serge Meimon

In this paper, we present a novel concept for a multi-channel swept source optical coherence tomography (OCT) system based on photonic integrated circuits (PICs). At the core of this concept is a low-loss polarization dependent path routing…

We present the first demonstration of shot-noise limited supercontinuum-based spectral domain optical coherence tomography (SD-OCT) with axial resolution of 5.9 $\mu$m at a center wavelength of 1370 nm. Current supercontinuum-based SD-OCT…

In high-performance computing (HPC) environments, particularly in synchrotron radiation facilities, vast amounts of X-ray images are generated. Processing large-scale X-ray Computed Tomography (X-CT) datasets presents significant…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Amarjit Singh , Kento Sato , Kohei Yoshida , Kentaro Uesugi , Yasumasa Joti , Takaki Hatsui , Andrès Rubio Proaño

Wavefront shaping is a powerful method to refocus light through a scattering medium. Its application to large spectral bandwidths or multiple wavelengths refocusing for nonlinear bio-imaging in-depth is however limited by spectral…

The emerging technique of mid-infrared optical coherence tomography (MIR-OCT) takes advantage of the reduced scattering of MIR light in various materials and devices, enabling tomographic imaging at deeper penetration depths. Because of…

In some medical imaging tasks and other settings where only small parts of the image are informative for the classification task, traditional CNNs can sometimes struggle to generalise. Manually annotated Regions of Interest (ROI) are…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Alessandro Fontanella , Antreas Antoniou , Wenwen Li , Joanna Wardlaw , Grant Mair , Emanuele Trucco , Amos Storkey

Acousto-optic imaging (AOI) enables optical-contrast imaging deep inside scattering samples via localized ultrasound-modulation of scattered light. While AOI allows optical investigations at depths, its imaging resolution is inherently…

Optics · Physics 2021-01-26 Moriya Rosenfeld , Daniel Doktofsky , Gil Weinberg , Yunzhe Li , Lei Tian , Ori Katz