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X-Ray Phase-Contrast Imaging (PCI) yields absorption, differential phase, and dark-field images. Computed Tomography (CT) of grating-based PCI can in principle provide high-resolution soft-tissue contrast. Recently, grating-based PCI took…

In this work, we present a method for synthetic CT (sCT) generation from zero-echo-time (ZTE) MRI aimed at structural and quantitative accuracies of the image, with a particular focus on the accurate bone density value prediction. We…

Region-of-Interest (ROI) tomography aims at reconstructing a region of interest $C$ inside a body using only x-ray projections intersecting $C$ with the goal to reduce overall radiation exposure when only a small specific region of the body…

Mathematical Physics · Physics 2016-03-23 Robert Azencott , Bernhard G. Bodmann , Tasadduk Chowdhury , Demetrio Labate , Anando Sen , Daniel Vera

This work presents a high-resolution X-ray microtomography system that uses commercial off-the-shelf (COTS) CMOS image sensors as direct detectors, relying on the sensor s intrinsic resolution to achieve tomographic reconstructions without…

Image and Video Processing · Electrical Eng. & Systems 2026-05-29 Damian L. Corzi , Jose Lipovetzky , Fabricio Alcalde Bessia , German Mato , Andres Cicuttin , Maria L. Crespo , Martin Perez , Mariano Gomez Berisso

We report on a technically simple approach to achieve high-resolution and high-sensitivity Fourier-domain OCT imaging in the mid-infrared range. The proposed OCT system employs an InF3 supercontinuum source. A specially designed dispersive…

Optics · Physics 2021-09-15 Ivan Zorin , Paul Gattinger , Andrii Prylepa , Bettina Heise

The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here…

A compact Inverse Compton Light Source (ICLS) design is presented, with flux and brilliance orders of magnitude beyond conventional laboratory-scale sources and other compact ICLS designs. This design utilizes the physics of inverse Compton…

Accelerator Physics · Physics 2018-08-29 K. E. Deitrick , G. A. Krafft , B. Terzić , J. R. Delayen

Spectral photon-counting X-ray CT (sCT) opens up new possibilities for the quantitative measurement of materials in an object, compared to conventional energy-integrating CT or dual energy CT. However, achieving reliable and accurate…

Image and Video Processing · Electrical Eng. & Systems 2020-07-15 Bingqing Xie , Pei Niu , Ting Su , Valérie Kaftandjian , Loic Boussel , Philippe Douek Feng Yang , Philippe Duvauchelle , Yuemin Zhu

All-optical Compton sources combine laser wakefield accelerators and intense scattering pulses to generate ultrashort bursts of backscattered radiation. The scattering pulse plays the role of a short-period undulator in which relativistic…

Accelerator Physics · Physics 2023-05-25 Andreas Döpp , Igor Andriyash , Kim Ta Phuoc

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and…

Medical Physics · Physics 2019-07-02 Cerine Lal , Hrebesh M Subhash , Sergey Alexandrov , Martin J Leahy

The vast volume of medical image data necessitates efficient compression techniques to support remote healthcare services. This paper explores Region of Interest (ROI) coding to address the balance between compression rate and image…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Utkarsh Prakash Srivastava , Toshiaki Fujii

Optical coherence tomography (OCT) microscope (OCM) uses a high-numerical-aperture objective to achieve cellular-level lateral resolution. However, its practical imaging depth range is limited by the depth of focus (DOF). Although…

The increasingly demand for machining accuracy and product quality excites a great interest in high-resolution non-destructive testing (NDT) methods, but spatial resolution of conventional high-energy computed tomography (CT) is limited to…

Photon counting detection is a promising approach toward effectively reducing the radiation dose in x-ray computed tomography (CT). Full CT reconstruction from a fraction of the detected photons required by scintillation-based detectors has…

Medical Physics · Physics 2020-08-24 Zheyuan Zhu , Hsin-Hsiung Huang , Shuo Pang

Purpose: The goal is to develop a new architecture for computed tomography (CT) which is at an ultra-low-dose for developing countries, especially in rural areas. Methods: The proposed scheme is inspired by the recently developed…

Medical Physics · Physics 2013-12-23 Fenglin Liu , Hengyong Yu , Wenxiang Cong , Ge Wang

For the first time, we demonstrate the application of an inverse Compton scattering X-ray Source, driven by a laser-plasma accelerator, to image an additively manufactured component. X-rays with a mean energy of 380 keV were produced and…

Non-destructive testing (NDT) is crucial for ensuring product quality and safety across various industries. Conventional methods such as ultrasonic, terahertz, and X-ray imaging have limitations in terms of probe-contact requirement, depth…

Optical coherence tomography (OCT) is a high-resolution three-dimensional imaging technique that enables non-destructive measurements of surface and subsurface microstructures. Recent developments of OCT operating in the mid-infrared (MIR)…

Optics · Physics 2020-07-15 Ivan Zorin , Rong Su , Bettina Heise , Bernhard Lendl , Markus Brandstetter

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Medical Physics · Physics 2025-01-03 Ziju Shen , Haimiao Zhang , Bin Dong , Jun Qiu , Yunxiang Li , Zhili Cui

Mid-infrared light scatters much less than shorter wavelengths, allowing greatly enhanced penetration depths for optical imaging techniques such as optical coherence tomography (OCT). However, both detection and broadband sources in the…

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