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Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5,6] certain simplifying…

Medical Physics · Physics 2024-02-23 Leopold Veselka , Lisa Krainz , Leonidas Mindrinos , Wolfgang Drexler , Peter Elbau

X-ray diffraction tomography (XDT) resolves spatially-variant XRD profiles within macroscopic objects, and provides improved material contrast compared to the conventional transmission-based computed tomography (CT). However, due to the…

Medical Physics · Physics 2019-01-04 Zheyuan Zhu , Alexander Katsevich , Shuo Pang

Deep learning has been successfully applied to OCT segmentation. However, for data from different manufacturers and imaging protocols, and for different regions of interest (ROIs), it requires laborious and time-consuming data annotation…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Haoran Zhang , Jianlong Yang , Ce Zheng , Shiqing Zhao , Aili Zhang

Optical Coherence Tomography (OCT) is one of the most emerging imaging modalities that has been used widely in the field of biomedical imaging. From its emergence in 1990's, plenty of hardware and software improvements have been made. Its…

Computer Vision and Pattern Recognition · Computer Science 2014-11-18 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Spectral domain optical coherence tomography (OCT) offers high resolution multidimensional imaging, but generally suffers from defocussing, intensity falloff and shot noise, causing artifacts and image degradation along the imaging depth.…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Jonathan H. Mason , Yvonne Reinwald , Ying Yang , Sarah Waters , Alicia El Haj , Pierre O. Bagnaninchi

Objective: There exist several X-ray computed tomography (CT) scanning strategies to reduce a radiation dose, such as (1) sparse-view CT, (2) low-dose CT, and (3) region-of-interest (ROI) CT (called interior tomography). To further reduce…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Yoseob Han , Dufan Wu , Kyungsang Kim , Quanzheng Li

The limits for adaptive-optics (AO) imaging at high contrast and high resolution are determined by residual phase errors from non-common-path aberrations not sensed by the wavefront sensor, especially for integral field spectrographs, where…

Instrumentation and Methods for Astrophysics · Physics 2015-06-22 Benjamin Pope , Niranjan Thatte , Rick Burruss , Matthias Tecza , Fraser Clarke , Garret Cotter

Thoracic aortic dissection and aneurysms are the most lethal diseases of the aorta. The major hindrance to treatment lies in the accurate analysis of the medical images. More particularly, aortic segmentation of the 3D image is often…

Image and Video Processing · Electrical Eng. & Systems 2026-01-14 Loris Giordano , Ine Dirks , Tom Lenaerts , Jef Vandemeulebroucke

X-ray ptychography allows for large fields to be imaged at high resolution at the cost of additional computational expense due to the large volume of data. Given limited information regarding the object, the acquired data often has an…

Image and Video Processing · Electrical Eng. & Systems 2022-07-01 Dergan Lin , Yi Jiang , Junjing Deng , Zichao Wendy Di

Robotic laser systems offer the potential for sub-millimeter, non-contact, high-precision tissue resection, yet existing platforms lack volumetric planning and intraoperative feedback. We present RATS (Robot-Assisted Tissue Surgery), an…

We propose a new acquisition geometry for electron density reconstruction in three dimensional X-ray Compton imaging using a monochromatic source. This leads us to a new three dimensional inverse problem where we aim to reconstruct a real…

Functional Analysis · Mathematics 2018-07-04 James Webber , William Lionheart

Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Pooya Khosravi , Kun Han , Anthony T. Wu , Arghavan Rezvani , Zexin Feng , Xiaohui Xie

Optical coherence tomography (OCT) uses low-coherence reflectometry to obtain cross-sectional images of inhomogeneous media, such as biological tissue. OCT is particularly useful in the biomedical ea, since the imaging can be performed…

Medical Physics · Physics 2018-03-01 Takahisa Mitsui , Kenichiro Aoki

Multiple light scattering in tissue limits the penetration of optical coherence tomography (OCT) imaging. Here, we present in-vivo OCT imaging of a live mouse using wavefront shaping to enhance the penetration depth. A digital micro-mirror…

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

Numerical Analysis · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

X-ray fluorescence computed tomography (XFCT) is a molecular imaging technique of x-ray photons, which can be used to sense different elements or nanoparticle (NP) agents inside deep samples or tissues. XFCT has been an active research…

Medical Physics · Physics 2021-02-01 Ignacio O. Romero , Yile Fang , Michael Lun , Changqing Li

We lay the foundations for a new fast method to reconstruct the electron density in x-ray scanning applications using measurements in the dark field. This approach is applied to a type of machine configuration with fixed energy sensitive…

Numerical Analysis · Mathematics 2015-05-08 James Webber

Computed tomography (CT) is a widely used medical imaging technique to scan internal structures of a body, typically involving collimation and mechanical rotation. Compton scatter tomography (CST) presents an interesting alternative to…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Ishak Ayad , Cécilia Tarpau , Javier Cebeiro , Maï K. Nguyen

Cryo-electron tomography (cryo-ET) enables high resolution, three-dimensional reconstruction of biological structures, including membranes and membrane proteins. Identification of regions of interest (ROIs) is central to scientific imaging,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Xingyi Cheng , Julien Maufront , Aurélie Di Cicco , Daniël M. Pelt , Manuela Dezi , Daniel Lévy

Computed tomography for region-of-interest (ROI) reconstruction has advantages of reducing X-ray radiation dose and using a small detector. However, standard analytic reconstruction methods suffer from severe cupping artifacts, and existing…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Yoseob Han , Jong Chul Ye