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In many machine learning tasks, learning a good representation of the data can be the key to building a well-performant solution. This is because most learning algorithms operate with the features in order to find models for the data. For…

Machine Learning · Computer Science 2020-05-22 David Charte , Francisco Charte , María J. del Jesus , Francisco Herrera

Recently, there has been great success in applying deep neural networks on graph structured data. Most work, however, focuses on either node- or graph-level supervised learning, such as node, link or graph classification or node-level…

Machine Learning · Computer Science 2021-12-15 Robin Winter , Frank Noé , Djork-Arné Clevert

Recent advances in learning aligned multimodal representations have been primarily driven by training large neural networks on massive, noisy paired-modality datasets. In this work, we ask whether it is possible to achieve similar results…

Machine Learning · Computer Science 2022-10-11 Elan Rosenfeld , Preetum Nakkiran , Hadi Pouransari , Oncel Tuzel , Fartash Faghri

The problem of linking functional connectomics to behavior is extremely challenging due to the complex interactions between the two distinct, but related, data domains. We propose a coupled manifold optimization framework which projects…

Machine Learning · Computer Science 2020-07-07 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

Single-cell trajectory analysis aims to reconstruct the biological developmental processes of cells as they evolve over time, leveraging temporal correlations in gene expression. During cellular development, gene expression patterns…

Applications · Statistics 2026-03-30 Junhao Zhu , Kevin Zhang , Zhaolei Zhang , Dehan Kong

Cell individualization has a vital role in digital pathology image analysis. Deep Learning is considered as an efficient tool for instance segmentation tasks, including cell individualization. However, the precision of the Deep Learning…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Huaqian Wu , Nicolas Souedet , Zhenzhen You , Caroline Jan , Cédric Clouchoux , Thierry Delzescaux

Autoencoders have seen wide success in domains ranging from feature selection to information retrieval. Despite this success, designing an autoencoder for a given task remains a challenging undertaking due to the lack of firm intuition on…

Neural and Evolutionary Computing · Computer Science 2020-04-17 Jeff Hajewski , Suely Oliveira , Xiaoyu Xing

Inspired by the complexity and diversity of biological neurons, a quadratic neuron is proposed to replace the inner product in the current neuron with a simplified quadratic function. Employing such a novel type of neurons offers a new…

Neural and Evolutionary Computing · Computer Science 2024-05-06 Jing-Xiao Liao , Bo-Jian Hou , Hang-Cheng Dong , Hao Zhang , Xiaoge Zhang , Jinwei Sun , Shiping Zhang , Feng-Lei Fan

Compositional Explanations is a method for identifying logical formulas of concepts that approximate the neurons' behavior. However, these explanations are linked to the small spectrum of neuron activations (i.e., the highest ones) used to…

Machine Learning · Computer Science 2023-10-31 Biagio La Rosa , Leilani H. Gilpin , Roberto Capobianco

Dealing with missing data in data analysis is inevitable. Although powerful imputation methods that address this problem exist, there is still much room for improvement. In this study, we examined single imputation based on deep…

Machine Learning · Computer Science 2020-04-07 Najmeh Abiri , Björn Linse , Patrik Edén , Mattias Ohlsson

Continual learning is essential for adapting models to new tasks while retaining previously acquired knowledge. While existing approaches predominantly focus on uni-modal data, multi-modal learning offers substantial benefits by utilizing…

Machine Learning · Computer Science 2025-11-11 Evelyn Chee , Wynne Hsu , Mong Li Lee

Conformal inference is a method that provides prediction sets for machine learning models, operating independently of the underlying distributional assumptions and relying solely on the exchangeability of training and test data. Despite its…

Methodology · Statistics 2025-10-01 Daniela Corbetta , Livio Finos , Ludwig Geistlinger , Davide Risso

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Recently developed technologies to generate single-cell genomic data have made a revolutionary impact in the field of biology. Multi-omics assays offer even greater opportunities to understand cellular states and biological processes.…

Genomics · Quantitative Biology 2022-01-19 Stefan Stanojevic , Yijun Li , Lana X. Garmire

One of the challenges of studying common neurological disorders is disease heterogeneity including differences in causes, neuroimaging characteristics, comorbidities, or genetic variation. Normative modelling has become a popular method for…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Ana Lawry Aguila , James Chapman , Andre Altmann

High-content screening uses large collections of unlabeled cell image data to reason about genetics or cell biology. Two important tasks are to identify those cells which bear interesting phenotypes, and to identify sub-populations enriched…

Machine Learning · Computer Science 2015-01-08 Lee Zamparo , Zhaolei Zhang

In neuroscience research, achieving single-neuron matching across different imaging modalities is critical for understanding the relationship between neuronal structure and function. However, modality gaps and limited annotations present…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Wenwei Li , Liyi Cai , Wu Chen , Anan Li

Autoencoders are among the earliest introduced nonlinear models for unsupervised learning. Although they are widely adopted beyond research, it has been a longstanding open problem to understand mathematically the feature extraction…

Machine Learning · Computer Science 2021-02-17 Phan-Minh Nguyen

Large-scale models have exhibited remarkable capabilities across diverse domains, including automated medical services and intelligent customer support. However, as most large models are trained on single-modality corpora, enabling them to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Hao Sun , Yu Song , Jiaqing Liu , Jihong Hu , Yen-Wei Chen , Lanfen Lin

The comparison of heterogeneous samples extensively exists in many applications, especially in the task of image classification. In this paper, we propose a simple but effective coupled neural network, called Deeply Coupled Autoencoder…

Computer Vision and Pattern Recognition · Computer Science 2014-02-11 Wen Wang , Zhen Cui , Hong Chang , Shiguang Shan , Xilin Chen
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