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We propose a magnetic resonance (MR)-based method for estimation of continuous linear attenuation coefficients (LAC) in positron emission tomography (PET) using a physical compartmental model and ultrashort echo time (UTE)/multi-echo Dixon…

Materials with acoustic quantities similar to soft-tissue are essential as tissue-mimicking materials for diagnostic ultrasound (US). Acoustic quantity consists of the sound velocity (cus), acoustic impedance (AI) and attenuation…

Purpose: To develop and validate a phantom for diagnostic ultrasound (US) scanners by embedding targets in gel wax to determine the image uniformity, lateral and axial resolution, and diameter of a stainless-steel disc. Materials and…

We fabricated compact low-pass stainless-steel powder filters for use in low-noise measurements at cryogenic temperatures and investigated their attenuation characteristics for different wire lengths, shapes, and preparation methods up to…

Instrumentation and Detectors · Physics 2016-09-21 Sung Hoon Lee , Soon-Gul Lee

Transcranial focused ultrasound applications often use simulations that require accurate acoustic properties, which can be related to computed tomography (CT) Hounsfield Units (HU). However, clinical CT is insensitive to microstructure.…

Medical Physics · Physics 2025-12-11 Samuel Clinard , Taylor Webb , Henrik Odéen , Dennis L. Parker , Douglas A. Christensen

The capabilities of additive manufacturing have facilitated the design and production of mechanical metamaterials with diverse unit cell geometries. Establishing linkages between the vast design space of unit cells and their effective…

Computational Engineering, Finance, and Science · Computer Science 2025-05-05 Hooman Danesh , Maruthi Annamaraju , Tim Brepols , Stefanie Reese , Surya R. Kalidindi

Carbon ion therapy have the ability to overcome the limitation of convertional radiotherapy due to its most energy deposition in selective depth, usually called Bragg peak, which results in increased biological effectiness. During carbon…

Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…

\textit{Objective:} Gadolinium-based contrast agents (GBCAs) have been widely used to better visualize disease in brain magnetic resonance imaging (MRI). However, gadolinium deposition within the brain and body has raised safety concerns…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Chao Chen , Catalina Raymond , Bill Speier , Xinyu Jin , Timothy F. Cloughesy , Dieter Enzmann , Benjamin M. Ellingson , Corey W. Arnold

This paper reports on the derivation and implementation of a shape optimization procedure for the minimization of hemolysis induction in biomedical devices. Hemolysis is a blood damaging phenomenon that may occur in mechanical…

Fluid Dynamics · Physics 2021-01-27 Georgios Bletsos , Niklas Kühl , Thomas Rung

Objective: Gadolinium-based contrast agents (GBCAs) are commonly used in MRI scans of patients with gliomas to enhance brain tumor characterization using T1-weighted (T1W) MRI. However, there is growing concern about GBCA toxicity. This…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Zach Eidex , Mojtaba Safari , Richard L. J. Qiu , David S. Yu , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Current methods for magnetic resonance-based positron emission tomography attenuation correction (PET-MR AC) are time consuming, and less able than computed tomography (CT)-based AC methods to capture inter-individual variability and skull…

We present here the improved crystallographic/geometric compatibility and magnetocaloric reversibility by measurement of magnetic entropy change using different protocols in 10% Pt substituted Ni2Mn1.4In0.6 magnetic shape memory alloy. The…

Materials Science · Physics 2020-04-07 K. K. Dubey , P. Devi , Anupam K. Singh , Sanjay Singh

Deep-learning-based MR-to-CT synthesis can estimate the electron density of tissues, thereby facilitating PET attenuation correction in whole-body PET/MR imaging. However, whole-body MR-to-CT synthesis faces several challenges including the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Jiaxu Zheng , Zhenrong Shen , Lichi Zhang , Qun Chen

Recently, 3D printing has been widely used to fabricate medical imaging phantoms. So far, various rigid 3D printable materials have been investigated for their radiological properties and efficiency in imaging phantom fabrication. However,…

An attention guided scheme for metal artifact correction in MRI using deep neural network is proposed in this paper. The inputs of the networks are two distorted images obtained with dual-polarity readout gradients. With MR image generation…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Jee Won Kim , Kinam Kwon , Byungjai Kim , HyunWook Park

CT perfusion imaging (CTP) plays an important role in decision making for the treatment of acute ischemic stroke with large vessel occlusion. Since the CT perfusion scan time is approximately one minute, the patient is exposed to a…

Medical Physics · Physics 2021-11-04 Vojtěch Kulvait , Philip Hoelter , Arnd Doerfler , Georg Rose

MRI offers outstanding soft tissue contrast that may reduce uncertainties in target and organ-at-risk delineation and enable online adaptive image-guided treatment. Spatial distortions resulting from non-linearities in the gradient fields…

Contrast-enhanced (CE) T1-weighted MRI is central to neuro-oncologic diagnosis but requires gadolinium-based agents, which add cost and scan time, raise environmental concerns, and may pose risks to patients. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Bastian Brandstötter , Erich Kobler

Structural MRI-to-amyloid PET synthesis has been proposed as a non-invasive alternative for amyloid assessment in Alzheimer's disease (AD). However, reported performance of identical models varies widely across studies, and increasingly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Louise E. G. Baron , Ross Callaghan , David M. Cash , Philip S. J. Weston , Hojjat Azadbakht , Hui Zhang