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PET image reconstruction is challenging due to the ill-poseness of the inverse problem and limited number of detected photons. Recently deep neural networks have been widely and successfully used in computer vision tasks and attracted…
Accurate quantification of cerebral blood flow (CBF) is essential for the diagnosis and assessment of a wide range of neurological diseases. Positron emission tomography (PET) with radiolabeled water (15O-water) is considered the…
Ultra-low-dose CT (ULDCT) imaging can greatly reduce patient radiation exposure, but the resulting scans suffer from severe structured and random noise that degrades image quality. To address this challenge, we propose a novel Plug-and-Play…
Pharmaceutical treatments can slow bone degradation, thus reducing the fracture risk inherent in osteoporosis. Antiresorptive treatments block the over-activation of osteoclasts vs osteoblasts, but the resulting decrease in bone remodeling…
Metal artifacts caused by the presence of metallic implants tremendously degrade the reconstructed computed tomography (CT) image quality, affecting clinical diagnosis or reducing the accuracy of organ delineation and dose calculation in…
Introduction: Terbium-149 ($^{149}$Tb) is a promising radionuclide for targeted $\alpha$ therapy that has a non-zero branching ratio (BR) for positron decay. However, its relatively low positron branching fraction and multiple prompt…
Purpose: The aim of this work was, a) to assess two treatment planning strategies for accounting CT-artifacts introduced by temporary tissue-expanders(TTEs); b) to evaluate the dosimetric impact of two commercially available and one novel…
Objective. This study investigates the best achievable performance of a brain-dedicated PET system with high resolution and sensitivity by evaluating different detector configurations, while maintaining a practical system design suitable…
The presence of metallic implants often introduces severe metal artifacts in the X-ray CT images, which could adversely influence clinical diagnosis or dose calculation in radiation therapy. In this work, we present a novel…
Positron Emission Tomography (PET) is an imaging method that can assess physiological function rather than structural disturbances by measuring cerebral perfusion or glucose consumption. However, this imaging technique relies on injection…
Background Resonance frequency analyses and quantitative ultrasound methods have been suggested to assess dental implant primary stability. PurposeThe purpose of this study was to compare the results obtained using these two techniques…
Accelerating Magnetic Resonance Imaging (MRI) reduces scan time but often degrades image quality. While Implicit Neural Representations (INRs) show promise for MRI reconstruction, they struggle at high acceleration factors due to weak prior…
In positron emission tomography acquisition (PET), sensitivity along a line of response can vary due to crystal geometrical arrangements in the scanner and/or detector inefficiencies, leading to severe artefacts in the reconstructed image.…
Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…
Metadamping is the phenomenon of either enhanced or diminished intrinsic dissipation in a material stemming from the material's internal structural dynamics. It has been previously shown that a locally resonant elastic metamaterial may be…
Metal artifacts in CT slices have long posed challenges in medical diagnostics. These artifacts degrade image quality, resulting in suboptimal visualization and complicating the accurate interpretation of tissues adjacent to metal implants.…
Medical imaging modalities including magnetic resonance imaging (MRI), computed tomography (CT), and ultrasound are essential for accurate diagnosis and treatment planning in modern healthcare. However, noise contamination during image…
Purpose: This study presents a variable resolution (VR) sampling and deep learning reconstruction approach for multi-spectral MRI near metal implants, aiming to reduce scan times while maintaining image quality. Background: The rising use…
Information about tissue oxygen saturation ($StO_2$) and other related important physiological parameters can be extracted from diffuse reflectance spectra measured through non-contact imaging. Three analytical optical reflectance models…
Purpose: Magnetization transfer saturation (MTsat) mapping is commonly used to examine the macromolecular content of brain tissue. This study compared variable flip angle (VFA) T1 mapping against compressed sensing (cs)MP2RAGE T1 mapping…