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The flow dynamics of red blood cells in vivo in blood capillaries and in vitro in microfluidic channels is complex. Cells can obtain differnet shapes such as discoid, parachute, slipper-like shapes and various intermediate states depending…

Biological Physics · Physics 2023-04-17 Andreas Link , a Irene Luna Pardo , Bernd Porr , Thomas Franke

Sorting cells based on their intrinsic properties is a highly desirable objective, since changes in cell deformability are often associated with various stress conditions and diseases. Deterministic lateral displacement (DLD) devices offer…

Fluid Dynamics · Physics 2024-06-03 Zunmin Zhang , Wei Chien , Ewan Henry , Dmitry A. Fedosov , Gerhard Gompper

Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…

Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

Optics · Physics 2022-01-26 Yi Xue , David Ren , Laura Waller

The ghost imaging (GI) technique, which has attracted attention as a highly sensitive and noise-resistant technique, employs a spatially modulated illuminating light and a single-pixel detector. Generally, the information acquired by GI is…

Optics · Physics 2025-05-23 Shuhei Yoshida

Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue, but lacks functional information. We present dynamic full-field optical coherence tomography to image living human induced…

For measurements designed to accurately determine layer thickness, there is a natural trade-off between sensitivity to optical thickness and lateral resolution due to the angular ray distribution required for a focused beam. We demonstrate…

Diffuse correlation spectroscopy (DCS) analyzes the autocorrelation function of photons scattered by red blood cells, enabling non-invasive, continuous measurement of deep tissue blood flow at the bedside. Multi-layer DCS models (two- and…

An approach reported recently by Alexandrov et al. on optical scatter imaging, termed digital Fourier microscopy (DFM), represents an adaptation of digital Fourier holography to selective imaging of biological matter. Holographic mode of…

Optics · Physics 2007-05-23 K. Y. T. Seet , P. Blazkiewicz , P. Meredith , A. V. Zvyagin

Blu-ray drive is an engineering masterpiece that integrates disc rotation, pickup head translation, and three lasers in a compact and portable format. Here we integrate a blood-coated image sensor with a modified Blu-ray drive for…

Instrumentation and Detectors · Physics 2022-10-28 Shaowei Jiang , Chengfei Guo , Tianbo Wang , Jia Liu , Pengming Song , Terrance Zhang , Ruihai Wang , Bin Feng , Guoan Zheng

The characterization of white blood cells (WBCs) is crucial for blood analyses and disease diagnoses. However, current standard techniques rely on cell labeling, a process which imposes significant limitations. Here we present…

Biological Physics · Physics 2015-05-12 Jonghee Yoon , Kyoohyun Kim , HyunJoo Park , Chulhee Choi , Seongsoo Jang , YongKeun Park

With the development of medical imaging technology and machine learning, computer-assisted diagnosis which can provide impressive reference to pathologists, attracts extensive research interests. The exponential growth of medical images and…

Computer Vision and Pattern Recognition · Computer Science 2020-10-08 Xiao Kang , Xingbo Liu , Xiushan Nie , Yilong Yin

With the advancement of computing resources, an increasing number of Neural Networks (NNs) are appearing for image detection and segmentation appear. However, these methods usually accept as input a RGB 2D image. On the other side, Light…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Ignacio de Loyola Páez-Ubieta , Edison P. Velasco-Sánchez , Santiago T. Puente

Color image steganography based on deep learning is the art of hiding information in the color image. Among them, image hiding steganography(hiding image with image) has attracted much attention in recent years because of its great…

Cryptography and Security · Computer Science 2021-12-30 Hai Su , Shan Yang , Shuqing Zhang , Songsen Yu

Digital holography is an interference-based imaging technique capable of recording both the amplitude and phase of an electromagnetic field. It can be obtained at the laser illumination wavelength, but also with second-harmonic generation,…

Differential phase contrast interior tomography allows for reconstruction of a refractive index distribution over a region of interest (ROI) for visualization and analysis of internal structures inside a large biological specimen. In this…

Medical Physics · Physics 2015-05-30 Wenxiang Cong , Ge Wang

Traditional supervised medical image segmentation models require large amounts of labeled data for training; however, obtaining such large-scale labeled datasets in the real world is extremely challenging. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Yunyao Lu , Yihang Wu , Reem Kateb , Ahmad Chaddad

Colorization involves the synthesis of colors on a target image while preserving structural content as well as the semantics of the target image. This is a well-explored problem in 2D with many state-of-the-art solutions. We propose a novel…

Image and Video Processing · Electrical Eng. & Systems 2020-04-27 Aradhya Neeraj Mathur , Apoorv Khattar , Ojaswa Sharma

Laser Doppler holography (LDH) is a full-field blood flow imaging technique able to reveal human retinal and choroidal blood flow with high temporal resolution. We here report on using LDH in the anterior segment of the eye without making…

Presented is a novel way to combine snapshot compressive imaging and lateral shearing interferometry in order to capture the spatio-spectral phase of an ultrashort laser pulse in a single shot. A deep unrolling algorithm is utilised for the…