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The Medipix3, a hybrid pixel detector with a silicon sensor, has been evaluated as a beam instrumentation device with proton and carbon ion measurements in the non-clinical research room (IR1) of MedAustron Ion Therapy Center. Protons…

Instrumentation and Detectors · Physics 2021-10-15 Navrit Johan Singh Bal , Claus Stefan Schmitzer , Andrea De Franco , Sascha Enke

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

No simulation of intense beam transport has accurately reproduced measurements at the level of beam halo. One potential explanation of this discrepancy is a lack of knowledge of the initial distribution of particles in six-dimensional…

Accelerator Physics · Physics 2022-08-15 Austin Hoover , Kiersten Ruisard , Alexander Aleksandrov , Alexander Zhukov , Sarah Cousineau

The goal of the first phase of the AWAKE \cite{AWAKE1,AWAKE2} experiment at CERN is to measure the self-modulation \cite{SMI} of the $\sigma_z = 12\,\rm{cm}$ long SPS proton bunch into microbunches after traversing $10\,\rm{m}$ of plasma…

Accelerator Physics · Physics 2017-02-22 Marlene Turner , B. Biskup , S. Burger , E. Gschwendtner , S. Mazzoni , A. Petrenko

Purpose: To introduce and evaluate the use of stable distributions as a means of describing the behavior of charged particle pencil beams in a medium, with specific emphasis on proton beam scanning (PBS). Methods: The proton pencil beams of…

Medical Physics · Physics 2018-03-29 Frank Van den Heuvel , Francesca Fiorini , Niek Schreuder , Ben George

Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…

Plasma scattering measurement is effective technique to observe low frequency density fluctuations excited in plasma. The spatial and wave number resolutions and the S/N ratio of measurement depend on the wavelength range, the size and the…

We investigate proton acceleration by a laser pulse obliquely incident on a double layer target via 3D PIC simulations. It is found that the proton beam energy spread changes by the laser irradiation position and it reaches a minimum at…

Focused ion beams (FIBs) are widely used in nanofabrication for applications such as circuit repair, ultra-thin lamella preparation, strain engineering, and quantum device prototyping. Although the lateral spread of the ion beam is often…

Instrumentation and Detectors · Physics 2025-11-04 M. G. Masteghin , Z. P. Aslam , A. P. Brown , M. J. Whiting , S. K. Clowes , R. P. Webb , D. C. Cox

Proton therapy is nowadays becoming a wide spread clinical practice in cancer therapy and sophisticated treatment planning systems are routinely used to exploit at best the ballistic properties of charged particles. The information on the…

Medical Physics · Physics 2015-05-14 S. Braccini , A. Ereditato , I. Kreslo , U. Moser , C. Pistillo , P. Scampoli , S. Studer

Transverse 2D phase space distribution of a 2.1 MeV, 5 mA H$^-$ beam is measured at the PIPIT test accelerator at Fermilab with an Allison scanner. The paper describes the design, calibration, and performance of the scanner as well as the…

Accelerator Physics · Physics 2021-02-03 C. Richard , J. -P. Carneiro , B. Hanna , L. Prost , A. Saini , V. Scarpine , A. Shemyakin

The distribution of the prompt gamma emissions induced by proton interactions in a target material carries information concerning the proton range and target composition. In order to image prompt gamma we present different approaches. The…

The Low Energy X-ray Telescope is a main payload on the Hard X-ray Modulation Telescope satellite. The swept charge device is selected for the Low Energy X-ray Telescope. As swept charge devices are sensitive to proton irradiation,…

Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose…

Charged particle beams are used in Particle Therapy (PT) to treat oncological patients due to their selective dose deposition in tissues and to their high biological effect in killing cancer cells with respect to photons and electrons used…

High-resolution lithographic techniques are often limited by low volumetric throughput, since there is no universal and scalable manufacturing process that can produce 3D metasurfaces. In this work, we demonstrate a high-speed holographic…

We report on the characterization by a position resolved laser system of small-pitch 3D diodes irradiated with neutrons up to an extremely high fluence of 3.5x10**16 neq cm**-2. We show that very high values of signal efficiency are…

Instrumentation and Detectors · Physics 2019-01-30 Roberto Mendicino , Maurizio Boscardin , Gian-Franco Dalla Betta

One of the possible ways to maintain the micrometer spatial resolution while performing ion beam analysis in the air is to increase the energy of ions. In order to explore capabilities and limitations of this approach, we have tested a…

Instrumentation and Detectors · Physics 2019-03-13 Milko Jakšić , Davit Chokheli , Stjepko Fazinić , Veljko Grilj , Natko Skukan , Ivan Sudić , Tonči Tadić , Tome Antičić

Charged particle therapy (CPT) is an advanced modality of radiation therapy which has grown rapidly worldwide, driven by recent developments in technology and methods of delivery. To ensure safe and high quality treatments, various…

Instrumentation and Detectors · Physics 2021-11-16 J. S. L. Yap , N. J. S. Bal , A. Kacperek , J. Resta López , C. P. Welsch

We report the design and test results of a beam monitor developed for online monitoring in hadron therapy. The beam monitor uses eight silicon pixel sensors, \textit{Topmetal-${II}^-$}, as the anode array. \textit{Topmetal-${II}^-$} is a…

Instrumentation and Detectors · Physics 2017-01-20 Zhen Wang , Shuguang Zou , Yan Fan , Jun Liu , Xiangming Sun , Dong Wang , Huili Kang , Daming Sun , Ping Yang , Hua Pei , Guangming Huang , Nu Xu , Chaosong Gao , Le Xiao
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