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A new regime is described for Radiation Pressure Acceleration of a thin foil by an intense laser beam of above 10^20 W/cm^2. Highly monoenergetic proton beams extending to GeV energies can be produced with very high efficiency using…

Plasma Physics · Physics 2009-11-13 A. P. L. Robinson , M. Zepf , S. Kar , R. G. Evans , C. Bellei

This study experimentally examines the effect and changes in the delivered fields, using water-equivalent phantoms with and without titanium (Ti) dental implants positioned along the primary beam path. We measure in detail the composition…

Medical Physics · Physics 2024-09-30 C. Balan , C. Granja , G. Mytsin , S. Shvidky , A. Molokanov , V. Chis , C. Oancea

A high precision beam monitor system based on silicon carbide PIN sensor is designed for China Spallation Neutron Source 1.6 GeV proton beam to monitor the proton beam fluence.The concept design of the beam monitor system is finished…

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

Medical Physics · Physics 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

Accurate dose distribution prediction is crucial in the radiotherapy planning. Although previous methods based on convolutional neural network have shown promising performance, they have the problem of over-smoothing, leading to prediction…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Xin Liao , Zhenghao Feng , Jianghong Xiao , Xingchen Peng , Yan Wang

Single-molecule based 3rd generation DNA sequencing technologies have been explored with tremendous effort, among which nanopore sequencing is considered as one of the most promising to achieve the goal of $1,000 genome project towards…

The ATLAS Forward Physics (AFP) project plans to install 3D silicon pixel detectors about 210 m away from the interaction point and very close to the beamline (2-3 mm). This implies the need of slim edges of about 100-200 $\mu$m width for…

Instrumentation and Detectors · Physics 2015-11-09 Jörn Lange , Emanuele Cavallaro , Sebastian Grinstein , Ivan Lopez Paz

The purpose of this study was to investigate the feasibility of extracting proton beams with two distinct energies within a single synchrotron cycle. The energy difference between the beams should be sufficient to use one beam as a range…

Accelerator Physics · Physics 2025-06-25 Alexander A. Pryanichnikov , Dmitry Shwartz , Jon Feldmand , Joao Seco , Maria Francesca Spadea

Detectors planned for use at the Large Hadron Collider will operate in a radiation field produced by beam collisions. To predict the radiation damage to the components of the detectors, prototype devices are irradiated at test beam…

Instrumentation and Detectors · Physics 2015-06-17 Prabhakar Palni , Martin Hoeferkamp , Aaron Taylor , Sandip Vora , Haley McDuff , Qufei Gu , Sally Seidel

Micro- or nano-structured targets are advantageous in enhancing and manipulating laser-proton acceleration, due to the increased absorption of laser energy and onset of direct laser acceleration for high-energy electrons. Here, we…

In this paper we report on a high current density ion beam profile diagnostics with a slit-based system as a reliable method, capable of high thermal load applications. The task arose in frames of a point-like neutron source development for…

Arrays of minibeams of protons and $^{12}$C in tissue-like media were modeled with Geant4 toolkit. A set of beam energies was used in simulations to provide a Spead-out Bragg peak (SOBP) extended by 6 cm in depth for protons as well as for…

Medical Physics · Physics 2024-09-23 I. A. Pshenichnov , U. A. Dmitrieva , S. D. Savenkov , A. O. Svetlichnyi

While stress visualization within 3-dimensional particles would greatly advance our understanding of the behaviors of complex particles, traditional photoelastic methods suffer from a lack of available technology for producing suitable…

For the in vivo range verification in proton therapy, it has been tried to measure the spatial distribution of the prompt gammas generated by the proton-induced interactions with the close relationship with the proton dose distribution.…

Medical Physics · Physics 2015-03-13 Wook-Geun Shin , Chul Hee Min , Jae-Ik Shin , Jong Hwi Jeong , Se Byeong Lee

Experimental studies of microdosimetry in therapeutic ion beams have been performed using several detectors. The differences among them lie on the shapes, the site sizes, and the material. Coin-shaped solid-state detectors made of silicon…

Instrumentation and Detectors · Physics 2020-05-11 Giulio Magrin

We propose to develop deep learning models that can predict Pareto optimal dose distributions by using any given set of beam angles, along with patient anatomy, as input to train the deep neural networks. We implement and compare two deep…

Medical Physics · Physics 2021-01-27 Gyanendra Bohara , Azar Sadeghnejad Barkousaraie , Steve Jiang , Dan Nguyen

A liquid isooctane (C$_{8}$H$_{18}$) filled ionization linear array for radiotherapy quality assurance has been designed, built and tested. The detector consists of 128 pixels, each of them with an area of 1.7 mm $\times$ 1.7 mm and a gap…

Medical Physics · Physics 2009-11-10 J. Pardo , L. Franco , F. Gomez , A. Iglesias , A. Pazos , J. Pena , R. Lobato , J. Mosquera , M. Pombar , J. Sendon

Accurate control and monitoring of the beam is essential for precise dose delivery to tumor tissues during radiotherapy. Real-time monitoring of ion beam profiles and positions improves beam control, patient safety, and treatment…

Advanced radiotherapy approaches such as FLASH irradiation and spatially fractionated radiotherapy (SFRT) show potential to improve the therapeutic ratio, yet their biological mechanisms and optimal delivery parameters remain uncertain.…

Objective: Quantify geometric and dosimetric accuracy of a novel prostate MR-to-MR deformable image registration (DIR) approach to support MR-guided adaptive radiation therapy dose accumulation. Approach: We evaluated DIR accuracy in 25…