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People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…
Repeated longitudinal measurements are commonly used to model long-term disease progression, and timing and number of assessments per patient may vary, leading to irregularly spaced and sparse data. Longitudinal trajectories may exhibit…
Acute psychological stress occurs in a wide range of everyday contexts, including transportation, occupational settings, and physical activity, where its reliable detection could enable adaptive system responses and support human…
Patients with hypoplastic left heart syndrome (HLHS) are born with an underdeveloped left heart. They typically receive a sequence of surgeries that result in a single ventricle physiology called the Fontan circulation. While these patients…
Many natural language processing tasks solely rely on sparse dependencies between a few tokens in a sentence. Soft attention mechanisms show promising performance in modeling local/global dependencies by soft probabilities between every two…
We consider a heterogeneous, globally coupled population of excitatory quadratic integrate-and-fire neurons with excitability adaptation due to a metabolic feedback associated with ketogenic diet, a form of therapy for epilepsy. Bifurcation…
In this paper, the robot-assisted Reminiscence Therapy (RT) is studied as a psychosocial intervention to persons with dementia (PwDs). We aim at a conversation strategy for the robot by reinforcement learning to stimulate the PwD to talk.…
Functional magnetic resonance imaging recordings in the resting-state (RS) from the human brain are characterized by spontaneous low-frequency fluctuations in the blood oxygenation level dependent signal that reveal functional connectivity…
The gold standard to assess respiration during sleep is polysomnography; a technique that is burdensome, expensive (both in analysis time and measurement costs), and difficult to repeat. Automation of respiratory analysis can improve test…
Reinforcement learning (RL) is a promising approach to generate treatment policies for sepsis patients in intensive care. While retrospective evaluation metrics show decreased mortality when these policies are followed, studies with…
Functional magnetic resonance imaging (fMRI) provides an indirect measurement of neuronal activity via hemodynamic responses that vary across brain regions and individuals. Ignoring this hemodynamic variability can bias downstream…
Formation of a pseudoknot in the conserved RNA core domain in the ribonucleoprotein human telomerase is required for function. In vitro experiments show that the pseudoknot (PK) is in equilibrium with an extended hairpin (HP) structure. We…
We determine the asymptotic relaxation rate of a Brownian particle in a harmonic potential perturbed by quenched Gaussian disorder, a simplified model for rugged energy landscapes in complex systems. Depending on the properties of the…
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. In the United States, more than 15.7 million Americans have been diagnosed with COPD, with 96% of individuals…
Parkinson's disease (PD) is a neurodegenerative condition characterized by notable motor and non-motor manifestations. The assessment tool known as the Unified Parkinson's Disease Rating Scale (UPDRS) plays a crucial role in evaluating the…
Long short-term memory (LSTM) has emerged as a definitive network for analyzing and inferring time series data. LSTM has the capability to extract spectral features and a mixture of temporal features. Due to this benefit, a similar feature…
Pressure-induced superconductivity was studied for a spin-ladder cuprate Sr$_2$Ca$_{12}$Cu$_{24}$O$_{41}$ using nuclear magnetic resonance (NMR) under pressures up to the optimal pressure 3.8 GPa. Pressure application leads to a…
Dynamic treatment recommendation systems based on large-scale electronic health records (EHRs) become a key to successfully improve practical clinical outcomes. Prior relevant studies recommend treatments either use supervised learning…
Remote photoplethysmography (rPPG) based physiological measurement has great application values in affective computing, non-contact health monitoring, telehealth monitoring, etc, which has become increasingly important especially during the…
Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…