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Powered lower limb exoskeletons are a viable solution for people with a spinal cord injury to regain mobility for their daily activities. However, the commonly employed rigid actuation and pre-programmed trajectories increase the risk of…

Stress-induced glucocorticoid elevation is a highly conserved response among vertebrates. This facilitates stress adaptation and the mode of action involves activation of the intracellular glucocorticoid receptor leading to the modulation…

Cell Behavior · Quantitative Biology 2017-04-28 L Dindia , J Murray , Erin Faught , T Davis , Zoya Leonenko , M Vijayan

Recordings from area V4 of monkeys have revealed that when the focus of attention is on a visual stimulus within the receptive field of a cortical neuron, two distinct changes can occur: The firing rate of the neuron can change and there…

Neurons and Cognition · Quantitative Biology 2007-05-23 Paul H. E. Tiesinga , Jean-Marc Fellous , Emilio Salinas , Jorge V. Jose , Terrence J. Sejnowski

The high motility of synaptic weights raises the question of how the brain can retain its functionality in the face of constant synaptic remodeling. Here we used the whisker system of rats and mice to study the interplay between synaptic…

Biological Physics · Physics 2024-02-01 Nimrod Sherf , Maoz Shamir

Abstract Objective In Genetic Absence Epilepsy Rats From Strasbourg ( GAERS s), epileptogenesis takes place during brain maturation and correlates with increased mRNA expression of D3 dopamine receptors (D3R). Whether these alterations are…

Metabolic syndrome (MetS) is a medication condition characterized by abdominal obesity, insulin resistance, hypertension and hyperlipidemia. It increases the risk of majority of chronic diseases, including type 2 diabetes mellitus, and…

Artificial Intelligence · Computer Science 2025-05-14 Yichen Zhao , Yuhua Wang , Xi Cheng , Junhao Fang , Yang Yang

Subjective tinnitus (ST) is generally assumed to be a consequence of hearing loss (HL). In animal studies acoustic trauma can lead to behavioral signs of ST, in human studies ST patients without increased hearing thresholds were found to…

Quantitative Methods · Quantitative Biology 2016-03-16 Patrick Krauss , Konstantin Tziridis , Achim Schilling , Claus Metzner , Holger Schulze

Human joint dynamic stiffness plays an important role in the stability of performance augmentation exoskeletons. In this paper, we consider a new frequency domain model of the human joint dynamics which features a complex value stiffness.…

Robotics · Computer Science 2020-05-04 Binghan He , Huang Huang , Gray C. Thomas , Luis Sentis

Neuronal networking supports complex brain functions, with neurotransmitters facilitating communication through chemical synapses. The release probability of neurotransmitters varies and is influenced by pre-synaptic neuronal activity.…

Neurons and Cognition · Quantitative Biology 2024-06-12 Zihan Liu , Flavia Nathaline Chanentia , Patteera Supvithayanong , Chi Chung Alan Fung

Simulation models of facial expressions propose that sensorimotor regions may increase the clarity of facial expressions representations in extrastriate areas. We monitored the event-related potential marker of visual working memory (VWM)…

Neurons and Cognition · Quantitative Biology 2018-08-14 Paola Sessa , Arianna Schiano Lomoriello , Roy Luria

Collective rhythmic dynamics from neurons is vital for cognitive functions such as memory formation but how neurons self-organize to produce such activity is not well understood. Attractor-based models have been successfully implemented as…

Neurons and Cognition · Quantitative Biology 2013-03-22 Mark Niedringhaus , Xin Chen , Katherine Conant , Rhonda Dzakpasu

Behavioral control over stressful stimuli induces resilience to future conditions when control is lacking. The medial prefrontal cortex(mPFC) is a critically important brain region required for plasticity of stress resilience. We found that…

Neurons and Cognition · Quantitative Biology 2012-04-06 Juan A. Varela , Jungang Wang , Andrew L. Varnell , Donald C. Cooper

Background: Tinnitus, defined as the conscious awareness of a noise without any identifiable corresponding external acoustic source, can be modulated by various factors. Among these factors, tinnitus patients commonly report drastic…

Neurons and Cognition · Quantitative Biology 2025-04-01 Robin Guillard , Vincent Philippe , Adam Hessas , Brice Faraut , Sarah Michiels , Minchul Park , Marco Congedo , Alain Londero , Damien Léger

We consider energy relaxation of the long-range spin glass model with sparse couplings, the so-called dilute Sherrington-Kirkpatrick (SK) model, starting from a random initial state. We consider the effect that modularity of the coupling…

Statistical Mechanics · Physics 2014-01-21 Jeong-Man Park , Michael W. Deem

Kinetic Riemann simulations have been completed to explore particle heating during guide field reconnection in the low-$\beta$ environment of the inner heliosphere and the solar corona. The reconnection exhaust is bounded by two rotational…

Plasma Physics · Physics 2019-09-04 Qile Zhang , J. F. Drake , M. Swisdak

One of solution-state Nuclear Magnetic Resonance (NMR)'s main weaknesses, is its relative insensitivity. J-driven Dynamic Nuclear Polarization (JDNP) was recently proposed for enhancing the sensitivity of solution-state NMR, by bypassing…

Chemical Physics · Physics 2023-08-07 Maria Grazia Concilio , Lucio Frydman

Parkinsonism leads to various electrophysiological changes in the basal ganglia-thalamocortical system (BGTCS), often including elevated discharge rates of the subthalamic nucleus (STN) and the output nuclei, and reduced activity of the…

Neurons and Cognition · Quantitative Biology 2018-01-08 Sacha Jennifer van Albada , Peter A. Robinson

Running title: Frontoparietal anodal tDCS reduces ketamine-induced oscillopathies.Abstract: During the prodromal phase of schizophrenia with its complex and insidious clinical picture, electroencephalographic recordings detect widespread…

Neurons and Cognition · Quantitative Biology 2020-10-14 Caroline Lahogue , Didier Pinault

Acute Kidney Injury (AKI), a sudden decline in kidney function, is associated with increased mortality, morbidity, length of stay, and hospital cost. Since AKI is sometimes preventable, there is great interest in prediction. Most existing…

Machine Learning · Computer Science 2019-03-06 Samuel J. Weisenthal , Caroline Quill , Samir Farooq , Henry Kautz , Martin S. Zand

Chronic diseases such as cancer, diabetes, heart diseases, chronic kidney disease (CKD) require a drug management system that ensures a stable and robust output of the patient's condition in response to drug dosage. In the case of CKD, the…

Quantitative Methods · Quantitative Biology 2020-08-21 Affan Affan , Tamer Inanc
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