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Related papers: The basic reproduction number, $R_0$, in structure…

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We analyze a Markovian SIR epidemic model where individuals either recover naturally or are diagnosed, leading to isolation and potential contact tracing. Our focus is on digital contact tracing via a tracing app, considering both its…

Probability · Mathematics 2026-01-14 Tom Britton , Dongni Zhang

We study a multitype SIR epidemic model where individuals are categorized into different types, and where infection spread is characterized by a next-generation matrix $M=\{m_{ij}\}$ with community fractions $\{\pi_j\}$ for the different…

Populations and Evolution · Quantitative Biology 2026-03-10 Andrea Bizzotto , Frank Ball , Tom Britton

Many infectious diseases can lead to re-infection. We examined the relationship between the prevalence of repeat infection and the basic reproductive number (R0). First we solved a generic, deterministic compartmental model of re-infection…

Populations and Evolution · Quantitative Biology 2019-03-15 Joshua Feldman , Sharmistha Mishra

The basic reproduction number R0 is a concept which originated in population dynamics, mathematical epidemiology, and ecology and is closely related to the mean number of children in branching processes.We offer below three new…

Populations and Evolution · Quantitative Biology 2023-11-30 Florin Avram , Rim Adenane , Lasko Basnarkov , Matthew Johnston

This paper studies the spread dynamics of a stochastic SIRS epidemic model with nonlinear incidence and varying population size, which is formulated as a piecewise deterministic Markov process. A threshold dynamic determined by the basic…

Dynamical Systems · Mathematics 2017-10-26 Dan Li , Shengqiang Liu , Jing'an Cui

Complex networks with pairwise connections have been vastly used for the modeling of interactions within systems. Although these type of models are capable to capture rich structures and different phases within a great variety of…

Statistical Mechanics · Physics 2022-09-14 Gerardo Palafox-Castillo , Arturo Berrones-Santos

The reproductive number R_0 (and its value after initial disease emergence R) has long been used to predict the likelihood of pathogen invasion, to gauge the potential severity of an epidemic, and to set policy around interventions.…

Populations and Evolution · Quantitative Biology 2020-06-29 Clara L. Shaw , David A. Kennedy

An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R 0 , is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a…

Populations and Evolution · Quantitative Biology 2023-05-30 Dmitry Gromov , Ingo Bulla , Ethan Obie Romero-Severson

We consider a continuous-time Markov chain model of SIR disease dynamics with two levels of mixing. For this so-called stochastic households model, we provide two methods for inferring the model parameters---governing within-household…

Populations and Evolution · Quantitative Biology 2018-02-07 James N. Walker , Joshua V. Ross , Andrew J. Black

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

Methodology · Statistics 2014-11-14 Tom Britton , Federica Giardina

Recent evidences show that individuals who recovered from COVID-19 can be reinfected. However, this phenomenon has rarely been studied using mathematical models. In this paper, we propose a SEIRE epidemic model to describe the spread of the…

Populations and Evolution · Quantitative Biology 2022-05-17 Shaoli Wang , Tengfei Wang , Ya-nen Qi , Fei Xu

We are interested in describing the infected size of the SIS Epidemic model using Birth-Death Markov process. The Susceptible-Infected-Susceptible (SIS) model is defined within a population of constant size $M$; the size is kept constant by…

Populations and Evolution · Quantitative Biology 2021-06-01 A. H. Nzokem

We consider a single outbreak susceptible-infected-recovered (SIR) model and corresponding estimation procedures for the effective reproductive number $\mathcal{R}(t)$. We discuss the estimation of the underlying SIR parameters with a…

Populations and Evolution · Quantitative Biology 2020-04-16 Ariel Cintrón-Arias , Carlos Castillo-Chávez , Luís M. A. Bettencourt , Alun L. Lloyd , H. T. Banks

A class of multiple-timescale asymptotic solutions to the equations of the susceptible-infected-recovered (SIR) model is presented for the case of high basic reproduction number, with the inverse of the latter employed as the expansion…

Populations and Evolution · Quantitative Biology 2025-12-25 Oleg B. Shiryaev

We develop a general modelling framework for compartmental epidemiological systems structured by continuous variables which are linked to the levels of expression of compartment-specific traits. We start by formulating an individual-based…

Populations and Evolution · Quantitative Biology 2025-08-14 Emanuele Bernardi , Tommaso Lorenzi , Mattia Sensi , Andrea Tosin

We consider an epidemiological SIR model and a positive threshold $M$. Using a parametric expression for the solution curve of the SIR model and the Lambert W function, we establish necessary and sufficient conditions on the basic…

Optimization and Control · Mathematics 2021-07-09 Andrés David Báez-Sánchez , Nara Bobko

We discuss the criticality in the stochastic SIR model for infectious diseases. We adopt the path-integral formalism for the propagation of infections among susceptible, infectious, and removed individuals, and perform the perturbative and…

Populations and Evolution · Quantitative Biology 2022-02-14 Shigehiro Yasui , Yutaka Hatakeyama , Yoshiyasu Okuhara

Branching processes are widely used to model evolutionary and population dynamics as well as the spread of infectious diseases. To characterize the dynamics of their growth or spread, the basic reproduction number $R_0$ has received…

Populations and Evolution · Quantitative Biology 2021-09-02 Johannes Pausch , Rosalba Garcia-Millan , Gunnar Pruessner

Since the last century, deterministic compartmental models have emerged as powerful tools to predict and control epidemic outbreaks, in many cases helping to mitigate their impacts. A key quantity for these models is the so-called Basic…

Populations and Evolution · Quantitative Biology 2022-11-03 Àlex Giménez-Romero , Rosa Flaquer-Galmés , Manuel A. Matias

Early in an infectious disease outbreak, timely and accurate estimation of the basic reproduction number ($R_0$) and the serial interval (SI) is critical for understanding transmission dynamics and informing public health responses. While…

Methodology · Statistics 2026-01-29 Tatiana Krikella , Jane M. Heffernan , Hanna Jankowski