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Compartmental models are valuable tools for investigating infectious diseases. Researchers building such models typically begin with a simple structure where compartments correspond to individuals with different epidemiological statuses,…

Populations and Evolution · Quantitative Biology 2023-07-21 Darren Flynn-Primrose , Steven C. Walker , Michael Li , Benjamin M. Bolker , David J. D. Earn , Jonathan Dushoff

Inference of the reproduction number through time is of vital importance during an epidemic outbreak. Typically, epidemiologists tackle this using observed prevalence or incidence data. However, prevalence and incidence data alone is often…

Methodology · Statistics 2026-03-16 Alicia Gill , Jere Koskela , Xavier Didelot , Richard G. Everitt

We consider the problem of estimating the reproduction number $R_t$ of an epidemic for populations where the probability of detection of cases depends on a known covariate. We argue that in such cases the normal empirical estimator can fail…

Applications · Statistics 2020-12-04 Guido Sanguinetti

Reproduction numbers, like the basic reproduction number $\mathcal{R}_0$, play an important role in the analysis and application of dynamic models, including contagion models and ecological population models. One difficulty in deriving…

Populations and Evolution · Quantitative Biology 2021-05-25 Paul J. Hurtado , Cameron Richards

In the real world, many complex systems interact with other systems. In addition, the intra- or inter-systems for the spread of information about infectious diseases and the transmission of infectious diseases are often not random, but with…

Physics and Society · Physics 2017-08-23 Junbo Jia , Zhen Jin , Xinchu Fu

A Markovian SIR (Susceptible-Infectious-Recovered) model is considered for the spread of an epidemic on a configuration model network, in which susceptible individuals may take preventive measures by dropping edges to infectious neighbours.…

Probability · Mathematics 2019-01-23 Frank Ball , Tom Britton , Ka Yin Leung , David Sirl

It is essential to understand the dynamics of epidemics in the presence of coexisting pathogens. There are various phenomenon that can effect the dynamics. In this paper, we formulate a mathematical model using different assumptions to…

Populations and Evolution · Quantitative Biology 2021-11-02 S. Ghersheen , V. Kozlov , U. Wennergren

Due to its ability to summarise 'real-time' epidemic behaviour, the time-dependent reproduction number, Rt, is a useful metric for tracking pathogen transmission and quantifying the effects of interventions during infectious disease…

Populations and Evolution · Quantitative Biology 2026-03-12 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

We consider a space-time SI epidemic model with infection age-dependent infectivity and non-local infections constructed on a grid of the torus $\mathbb{T}^1 =(0, 1]^d$, where the individuals may migrate from node to another. The migration…

Probability · Mathematics 2023-06-06 Anicet Mougabe-Peurkor , Étienne Pardoux , Ténan Yeo

Structured epidemic models can be formulated as first-order hyperbolic PDEs, where the "spatial" variables represent individual traits, called structures. For models with two structures, we propose a numerical technique to approximate…

Numerical Analysis · Mathematics 2021-09-08 Dimitri Breda , Simone De Reggi , Francesca Scarabel , Rossana Vermiglio , Jianhong Wu

We study that the breakdown of epidemic depends on some parameters, that is expressed in epidemic reproduction ratio number. It is noted that when $R_0 $ exceeds 1, the stochastic model have two different results. But, eventually the…

Statistics Theory · Mathematics 2018-03-19 Kurnia Susvitasari

The time-dependent reproduction number Rt can be used to track pathogen transmission and to assess the efficacy of interventions. This quantity can be estimated by fitting renewal equation models to time series of infectious disease case…

Populations and Evolution · Quantitative Biology 2025-01-30 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

The effective reproduction number, R(t), is a central point in the study of infectious diseases. It establishes in an explicit way the extent of an epidemic spread process in a population. The current estimation methods for the time…

Populations and Evolution · Quantitative Biology 2021-02-26 D. C. P. Jorge , J. F. Oliveira , J. G. V. Miranda , R. F. S. Andrade , S. T. R. Pinho

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

A simplified model for the growth of a population is studied in which random effects arise because reproducing individuals have a certain probability of surviving until the next breeding season and hence contributing to the next generation.…

Populations and Evolution · Quantitative Biology 2016-04-05 Henry C. Tuckwell

We introduce an extension to Kermack and McKendrick's classic susceptible-infected-recovered (SIR) model in epidemiology, whose underlying mechanism of infection consists of individuals attending randomly generated social gatherings. This…

Probability · Mathematics 2024-05-08 Roberto Cortez

Vector-borne diseases with reservoir cycles are complex to understand because new infections come from contacts of the vector with humans and different reservoirs. In this scenario, the basic reproductive number $\mathcal{R}^h_0$ of the…

Populations and Evolution · Quantitative Biology 2017-02-10 Esteban Vargas , Camilo Sanabria

The aim of this study is to propose a modified Susceptible-Exposed-Infectious-Removed (SEIR) model that describes the behaviour of symptomatic, asymptomatic and hospitalized patients of COVID-19 epidemic, including the effect of demographic…

We study a class of individual-based, fixed-population size epidemic models under general assumptions, e.g., heterogeneous contact rates encapsulating changes in behavior and/or enforcement of control measures. We show that the…

Probability · Mathematics 2023-07-04 Jean-Jil Duchamps , Félix Foutel-Rodier , Emmanuel Schertzer

We propose a new network-based SIR epidemic model in which transmission is modulated by a curvature-weighted contact matrix that encodes structural and geometric features of the underlying graph. The formulation encompasses both…

Dynamical Systems · Mathematics 2025-12-29 Marcilio Ferreira dos Santos
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