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Related papers: The basic reproduction number, $R_0$, in structure…

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In this paper, we study a reaction-diffusion vector-host epidemic model. We define the basic reproduction number $R_0$ and show that $R_0$ is a threshold parameter: if $R_0\le 1$ the disease free steady state is globally stable; if $R_0>1$…

Analysis of PDEs · Mathematics 2018-12-05 Pierre Magal , G. F. Webb , Yixiang Wu

A general stochastic model for susceptible -> infective -> recovered (SIR) epidemics in non homogeneous populations is considered. The heterogeneity is a very important aspect here since it allows more realistic but also more complex…

Populations and Evolution · Quantitative Biology 2020-08-13 Zeynep Gökçe İşlier , Wolfgang Hörmann , Refik Güllü

A basic reproduction number, $R_0$, is a concept encountered frequently in the study of ecological and epidemiological models. It is routinely used to determine the stability of an extinction or a disease-free fixed point or steady state.…

Functional Analysis · Mathematics 2026-02-12 Zachary Gregg , Patrick De Leenheer

The basic reproduction number, $R_0$, is a well-known quantifier of epidemic spread. However, a class of existing methods for estimating $R_0$ from incidence data early in the epidemic can lead to an over-estimation of this quantity. In…

Populations and Evolution · Quantitative Biology 2024-03-27 Wajid Ali , Christopher E. Overton , Robert R. Wilkinson , Kieran J. Sharkey

The Markovian approach, which assumes exponentially distributed interinfection times, is dominant in epidemic modeling. However, this assumption is unrealistic as an individual's infectiousness depends on its viral load and varies over…

Populations and Evolution · Quantitative Biology 2023-08-02 Qihui Yang , Joan Saldaña , Caterina Scoglio

A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g. reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such…

Probability · Mathematics 2011-12-21 Tom Britton , David Lindenstrand

This is a pedagogical paper on estimating the number of people that can be infected by one infectious person during an epidemic outbreak, known as the reproduction number. Knowing the number is crucial for developing policy responses. There…

Populations and Evolution · Quantitative Biology 2020-06-30 H. Susanto , V. R. Tjahjono , A. Hasan , M. F. Kasim , N. Nuraini , E. R. M. Putri , R. Kusdiantara , H. Kurniawan

A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

Populations and Evolution · Quantitative Biology 2017-09-05 Kristoffer Spricer , Pieter Trapman

In the face of an infectious disease, a key epidemiological measure is the basic reproduction number, which quantifies the average secondary infections caused by a single case in a susceptible population. In practice, the effective…

Physics and Society · Physics 2025-03-11 Xin-Jian Xu , Song-Jie He , Li-Jie Zhang

In this paper, we introduce a general numerical method to approximate the reproduction numbers of a large class of multi-group, age-structured, population models with a finite age span. To provide complete flexibility in the definition of…

Populations and Evolution · Quantitative Biology 2024-03-21 Simone De Reggi , Francesca Scarabel , Rossana Vermiglio

We study the Suscectible-Infected-Recovered-Susceptible (SIRS) epidemic model on deterministic networks. For connected but otherwise general interaction patterns and heterogeneous recovery and loss-of-immunity rates, we identify a…

Systems and Control · Electrical Eng. & Systems 2026-04-24 Giulia Gatti , Giacomo Como

The basic reproduction number ($R_0$) is a threshold parameter for disease extinction or survival in isolated populations. However no human population is fully isolated from other human or animal populations. We use compartmental models to…

Populations and Evolution · Quantitative Biology 2018-09-05 Angus McLure , Kathryn Glass

The effective reproduction number is an important descriptor of an infectious disease epidemic. In small populations, ideally we would estimate the effective reproduction number using a Markov Jump Process (MJP) model of the spread of…

Studies about epidemic modelling have been conducted since before 19th century. Both deterministic and stochastiic model were used to capture the dynamic of infection in the population. The purpose of this project is to investigate the…

Populations and Evolution · Quantitative Biology 2018-03-06 Kurnia Susvitasari

We discuss how the presence of a large set of asymptomatic infectives changes our estimate of the COVID-19 basic reproduction number, also known as $R_0$.

Populations and Evolution · Quantitative Biology 2020-04-14 Giuseppe Gaeta

This work provides a geometric version of the next-generation matrix method for obtaining the basic reproduction number of an epidemiological model. We exhibit a certain correspondence between any system of ODEs and Petri nets. We observe…

Populations and Evolution · Quantitative Biology 2025-08-12 Carlos Segovia

We propose two SIR models which incorporate sociological behavior of groups of individuals. It is these differences in behaviors which impose different infection rates on the individual susceptible populations, rather than biological…

Dynamical Systems · Mathematics 2022-07-26 Robert F. Allen , Katherine Heller , Matthew A. Pons

This paper presents a disease-severity-structured epidemic model with treatment necessary only to severe infective individuals to discuss the effect of the treatment capacity on the disease transmission. It is shown that a backward…

Populations and Evolution · Quantitative Biology 2021-10-05 Hiromu Gion , Yasuhisa Saito

Reproduction numbers are widely used for the estimation and prediction of epidemic spreading processes over networks. However, reproduction numbers do not enable estimation and prediction in individual communities within networks, and they…

Systems and Control · Electrical Eng. & Systems 2025-06-23 Baike She , Philip E. Paré , Matthew Hale

The main aim of the work is to present a general class of two time scales discrete-time epidemic models. In the proposed framework the disease dynamics is considered to act on a slower time scale than a second different process that could…

Dynamical Systems · Mathematics 2024-02-07 Luis Sanz-Lorenzo , Rafael Bravo de la Parra