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Related papers: Achieving GWAS with Homomorphic Encryption

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Privacy computing involves the extensive exchange and processing of encrypted data. For the parties involved in these interactions, how to determine the consistency of exchanged data without accessing the original data, ensuring tamper…

Cryptography and Security · Computer Science 2024-10-24 Huang Neng

Machine Learning (ML) has emerged as one of data science's most transformative and influential domains. However, the widespread adoption of ML introduces privacy-related concerns owing to the increasing number of malicious attacks targeting…

Machine Learning · Computer Science 2024-01-29 Eugene Frimpong , Khoa Nguyen , Mindaugas Budzys , Tanveer Khan , Antonis Michalas

Through genome-wide association studies (GWAS), disease susceptible genetic variables can be identified by comparing the genetic data of individuals with and without a specific disease. However, the discovery of these associations poses a…

Machine Learning · Computer Science 2023-08-15 Zhendong Sha , Yuanzhu Chen , Ting Hu

Legacy encryption systems depend on sharing a key (public or private) among the peers involved in exchanging an encrypted message. However, this approach poses privacy concerns. Especially with popular cloud services, the control over the…

Cryptography and Security · Computer Science 2017-10-09 Abbas Acar , Hidayet Aksu , A. Selcuk Uluagac , Mauro Conti

Despite the cloud enormous technical and financial advantages, security and privacy have always been the primary concern for adopting cloud computing facility, especially for government agencies and commercial sectors with high-security…

Cryptography and Security · Computer Science 2025-08-29 Yang Gao , Gang Quan , Soamar Homsi , Wujie Wen , Liqiang Wang

Homomorphic encryption (HE) enables privacy-preserving aggregation in federated learning (FL) by allowing the server to operate on encrypted data without decryption. Existing HE-over-the-air methods mainly rely on single-key HE schemes and…

Cryptography and Security · Computer Science 2026-05-29 Anthony Ayli , Khalil Harris , Jihad Fahs , Mohamad Assaad

Traditional GWAS has advanced our understanding of complex diseases but often misses nonlinear genetic interactions. Deep learning offers new opportunities to capture complex genomic patterns, yet existing methods mostly depend on feature…

Machine Learning · Computer Science 2025-07-08 Iqra Farooq , Sara Atito , Ayse Demirkan , Inga Prokopenko , Muhammad Rana

Machine Learning (ML) is making its way into fields such as healthcare, finance, and Natural Language Processing (NLP), and concerns over data privacy and model confidentiality continue to grow. Privacy-preserving Machine Learning (PPML)…

Cryptography and Security · Computer Science 2025-10-10 Kalyan Cheerla , Lotfi Ben Othmane , Kirill Morozov

Machine learning (ML) algorithms are increasingly important for the success of products and services, especially considering the growing amount and availability of data. This also holds for areas handling sensitive data, e.g. applications…

Cryptography and Security · Computer Science 2023-09-19 Martin Nocker , David Drexel , Michael Rader , Alessio Montuoro , Pascal Schöttle

Machine Learning (ML) alleviates the challenges of high-dimensional data analysis and improves decision making in critical applications like healthcare. Effective cancer type from high-dimensional genetic mutation data can be useful for…

Cryptography and Security · Computer Science 2022-04-13 Esha Sarkar , Eduardo Chielle , Gamze Gursoy , Leo Chen , Mark Gerstein , Michail Maniatakos

Meta-analysis of multiple genome-wide association studies (GWAS) is effective for detecting single or multi marker associations with complex traits. We develop a flexible procedure ("STAMP") based on mixture models to perform region based…

Methodology · Statistics 2018-01-01 Andriy Derkach , Ruth M. Pfeiffer

Combining data from several case-control genome-wide association (GWA) studies can yield greater efficiency for detecting associations of disease with single nucleotide polymorphisms (SNPs) than separate analyses of the component studies.…

Methodology · Statistics 2010-10-26 Ruth M. Pfeiffer , Mitchell H. Gail , David Pee

Copy number variants (CNVs) account for more polymorphic base pairs in the human genome than do single nucleotide polymorphisms (SNPs). CNVs encompass genes as well as noncoding DNA, making these polymorphisms good candidates for functional…

Methodology · Statistics 2010-10-26 Sebastian Zöllner , Tanya M. Teslovich

Biometric matching involves storing and processing sensitive user information. Maintaining the privacy of this data is thus a major challenge, and homomorphic encryption offers a possible solution. We propose a privacy-preserving…

Cryptography and Security · Computer Science 2021-11-25 Gaëtan Pradel , Chris Mitchell

Recently cloud-based graph convolutional network (GCN) has demonstrated great success and potential in many privacy-sensitive applications such as personal healthcare and financial systems. Despite its high inference accuracy and…

Cryptography and Security · Computer Science 2022-10-27 Ran Ran , Nuo Xu , Wei Wang , Gang Quan , Jieming Yin , Wujie Wen

The security of networked control systems (NCS) is receiving increasing attention from both cyber-security and system-theoretic perspectives. The former focuses on classical IT security goals such as confidentiality, integrity, and…

Cryptography and Security · Computer Science 2026-05-18 Philipp Binfet , Janis Adamek , Moritz Schulze Darup

This paper introduces a privacy-preserving distributed learning framework via private-key homomorphic encryption. Thanks to the randomness of the quantization of gradients, our learning with error (LWE) based encryption can eliminate the…

Cryptography and Security · Computer Science 2024-02-05 Guangfeng Yan , Shanxiang Lyu , Hanxu Hou , Zhiyong Zheng , Linqi Song

Machine Learning (ML) has become one of the most impactful fields of data science in recent years. However, a significant concern with ML is its privacy risks due to rising attacks against ML models. Privacy-Preserving Machine Learning…

Cryptography and Security · Computer Science 2024-09-11 Khoa Nguyen , Mindaugas Budzys , Eugene Frimpong , Tanveer Khan , Antonis Michalas

Incorporating fully homomorphic encryption (FHE) into the inference process of a convolutional neural network (CNN) draws enormous attention as a viable approach for achieving private inference (PI). FHE allows delegating the entire…

Cryptography and Security · Computer Science 2023-10-26 Jaiyoung Park , Donghwan Kim , Jongmin Kim , Sangpyo Kim , Wonkyung Jung , Jung Hee Cheon , Jung Ho Ahn

This paper aims to propose a novel machine learning (ML) approach incorporating Homomorphic Encryption (HE) to address privacy limitations in Unmanned Aerial Vehicles (UAV)-based face detection. Due to challenges related to distance,…

Cryptography and Security · Computer Science 2025-07-15 Nguyen Van Duc , Bui Duc Manh , Quang-Trung Luu , Dinh Thai Hoang , Van-Linh Nguyen , Diep N. Nguyen