English
Related papers

Related papers: Achieving GWAS with Homomorphic Encryption

200 papers

In this paper, association results from genome-wide association studies (GWAS) are combined with a deep learning framework to test the predictive capacity of statistically significant single nucleotide polymorphism (SNPs) associated with…

Computers and Society · Computer Science 2018-08-27 Casimiro Adays Curbelo Montañez , Paul Fergus , Almudena Curbelo Montañez , Carl Chalmers

With the rapid advancement of AI technology, we have seen more and more concerns on data privacy, leading to some cutting-edge research on machine learning with encrypted computation. Fully Homomorphic Encryption (FHE) is a crucial…

Cryptography and Security · Computer Science 2026-03-31 Longfei Guo , Pengbo Li , Ting Gao , Yonghai Zhong , Haojie Fan , Jinqiao Duan

Genome-Wide Association Studies (GWAS) help identify genetic variations in people with diseases such as Parkinson's disease (PD), which are less common in those without the disease. Thus, GWAS data can be used to identify genetic variations…

Genomics · Quantitative Biology 2023-04-07 Ali Amelia , Lourdes Pena-Castillo , Hamid Usefi

The widespread adoption of cloud infrastructures has revolutionised data storage and access. However, it has also raised concerns regarding the privacy of sensitive data stored in the cloud. To address these concerns, encryption techniques…

Cryptography and Security · Computer Science 2024-07-12 Ivone Amorim , Ivan Costa

For the vast majority of genome wide association studies (GWAS) published so far, statistical analysis was performed by testing markers individually. In this article we present some elementary statistical considerations which clearly show…

Applications · Statistics 2010-10-04 Florian Frommlet , Felix Ruhaltinger , Piotr Twarog , Malgorzata Bogdan

Homomorphic encryption (HE) enables calculating on encrypted data, which makes it possible to perform privacypreserving neural network inference. One disadvantage of this technique is that it is several orders of magnitudes slower than…

Cryptography and Security · Computer Science 2023-08-31 Wouter Legiest , Jan-Pieter D'Anvers , Furkan Turan , Michiel Van Beirendonck , Ingrid Verbauwhede

New cryptographic techniques such as homomorphic encryption (HE) allow computations to be outsourced to and evaluated blindfolded in a resourceful cloud. These computations often require private data owned by multiple participants, engaging…

Cryptography and Security · Computer Science 2020-08-13 Asma Aloufi , Peizhao Hu , Yongsoo Song , Kristin Lauter

One of the most important challenges in the analysis of high-throughput genetic data is the development of efficient computational methods to identify statistically significant Single Nucleotide Polymorphisms (SNPs). Genome-wide association…

Audio and speech data are increasingly used in machine learning applications such as speech recognition, speaker identification, and mental health monitoring. However, the passive collection of this data by audio listening devices raises…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-16 Tu Duyen Nguyen , Adrien Lesage , Clotilde Cantini , Rachid Riad

Deep learning has become a cornerstone of modern machine learning. It relies heavily on vast datasets and significant computational resources for high performance. This data often contains sensitive information, making privacy a major…

Cryptography and Security · Computer Science 2025-10-07 Nges Brian Njungle , Eric Jahns , Milan Stojkov , Michel A. Kinsy

Every commercially available, state-of-the-art neural network consume plain input data, which is a well-known privacy concern. We propose a new architecture based on homomorphic encryption, which allows the neural network to operate on…

Cryptography and Security · Computer Science 2025-02-28 Marcos Florencio , Luiz Alencar , Bianca Lima

The protection of privacy of individual-level information in genome-wide association study (GWAS) databases has been a major concern of researchers following the publication of "an attack" on GWAS data by Homer et al. (2008) Traditional…

Applications · Statistics 2014-02-10 Fei Yu , Stephen E. Fienberg , Aleksandra Slavković , Caroline Uhler

With the rapid development of AI technology, we have witnessed numerous innovations and conveniences. However, along with these advancements come privacy threats and risks. Fully Homomorphic Encryption (FHE) emerges as a key technology for…

Cryptography and Security · Computer Science 2023-09-19 Pengbo Li , Huifang Huang , Ting Gao , Jin Guo , Jinqiao Duan

Following the publication of an attack on genome-wide association studies (GWAS) data proposed by Homer et al., considerable attention has been given to developing methods for releasing GWAS data in a privacy-preserving way. Here, we…

Machine Learning · Statistics 2014-07-31 Fei Yu , Michal Rybar , Caroline Uhler , Stephen E. Fienberg

We propose a multi-bit leveled fully homomorphic encryption scheme using multivariate polynomial evaluations. The security of the scheme depends on the hardness of the Learning with Errors (LWE) problem. For homomorphic multiplication, the…

Cryptography and Security · Computer Science 2020-07-02 Uddipana Dowerah , Srinivasan Krishnaswamy

Genome Wide Association Studies (GWAS) are used to identify statistically significant genetic variants in case-control studies. GWAS typically use a p-value threshold of 5 x 10-8 to identify highly ranked single nucleotide polymorphisms…

Computational Engineering, Finance, and Science · Computer Science 2018-01-10 Paul Fergus , Casimiro Curbelo Montanez , Basma Abdulaimma , Paulo Lisboa , Carl Chalmers

Genome-wide association studies, in which as many as a million single nucleotide polymorphisms (SNP) are measured on several thousand samples, are quickly becoming a common type of study for identifying genetic factors associated with many…

Methodology · Statistics 2010-10-25 Charles Kooperberg , Michael LeBlanc , James Y. Dai , Indika Rajapakse

Privacy has gained a growing interest nowadays due to the increasing and unmanageable amount of produced confidential data. Concerns about the possibility of sharing data with third parties, to gain fruitful insights, beset enterprise…

Cryptography and Security · Computer Science 2020-11-16 Michela Iezzi

Homomorphic Encryption (HE) enables secure computation on encrypted data without decryption, allowing a great opportunity for privacy-preserving computation. In particular, domains such as healthcare, finance, and government, where data…

Hardware Architecture · Computer Science 2025-06-10 Matías Mazzanti , Esteban Mocskos , Augusto Vega , Pradip Bose

The widespread application of machine learning algorithms is a matter of increasing concern for the data privacy research community, and many have sought to develop privacy-preserving techniques for it. Among existing approaches, the…

Cryptography and Security · Computer Science 2024-04-01 Leonardo Neumann , Antonio Guimarães , Diego F. Aranha , Edson Borin