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Related papers: Achieving GWAS with Homomorphic Encryption

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DNA fingerprinting and matching for identifying suspects has been a common practice in criminal investigation. Such proceedings involve multiple parties such as investigating agencies, suspects and forensic labs. A major challenge in such…

Cryptography and Security · Computer Science 2024-09-24 Sankha Das

Searchable symmetric encryption (SSE) has been used to protect the confidentiality of genomic data while providing substring search and range queries on a sequence of genomic data, but it has not been studied for protecting single…

Cryptography and Security · Computer Science 2021-07-01 Sara Jafarbeiki , Amin Sakzad , Shabnam Kasra Kermanshahi , Raj Gaire , Ron Steinfeld , Shangqi Lai , Gad Abraham

In many scientific and engineering applications, one has to solve not one but a sequence of instances of the same problem. Often times, the problems in the sequence are linked in a way that allows intermediate results to be reused. A…

Mathematical Software · Computer Science 2013-05-01 Diego Fabregat-Traver , Paolo Bientinesi

Since the first theoretically feasible full homomorphic encryption (FHE) scheme was proposed in 2009, great progress has been achieved. These improvements have made FHE schemes come off the paper and become quite useful in solving some…

Cryptography and Security · Computer Science 2024-03-19 Yuqi Guo , Lin Li , Zhongxiang Zheng , Hanrui Yun , Ruoyan Zhang , Xiaolin Chang , Zhixuan Gao

Homomorphic encryption is a very useful gradient protection technique used in privacy preserving federated learning. However, existing encrypted federated learning systems need a trusted third party to generate and distribute key pairs to…

Cryptography and Security · Computer Science 2020-11-26 Hangyu Zhu , Rui Wang , Yaochu Jin , Kaitai Liang , Jianting Ning

Genetic algorithms are a population-based Meta heuristics. They have been successfully applied to many optimization problems. However, premature convergence is an inherent characteristic of such classical genetic algorithms that makes them…

Cryptography and Security · Computer Science 2010-07-15 Poonam Garg

Homomorphic encryption is an encryption scheme that allows computations to be evaluated on encrypted inputs without knowledge of their raw messages. Recently Ouyang et al. constructed a quantum homomorphic encryption (QHE) scheme for…

Quantum Physics · Physics 2019-04-29 Ching-Yi Lai , Kai-Min Chung

As quantum computing matures into a practical paradigm, the need for secure and private quantum computation on untrusted hardware becomes increasingly urgent. While classical fully homomorphic encryption has enabled computation over…

Quantum Physics · Physics 2026-04-22 Jon Hernández-Bueno , Oscar Lage , Marivi Higuero , Jasone Astorga

Genome-wide association studies (GWASs) have been extensively adopted to depict the underlying genetic architecture of complex diseases. Motivated by GWASs' limitations in identifying small effect loci to understand complex traits'…

Methodology · Statistics 2023-10-09 Xinran Qi , Michael E. Belloy , Jiaqi Gu , Xiaoxia Liu , Hua Tang , Zihuai He

The applications of Generative Artificial Intelligence (GenAI) and their intersections with data-driven fields, such as healthcare, finance, transportation, and information security, have led to significant improvements in service…

Cryptography and Security · Computer Science 2026-04-15 Anes Abdennebi , Nadjia Kara , Laaziz Lahlou

Graph neural networks (GNNs) have demonstrated remarkable performance in various graph-based machine learning tasks by effectively modeling high-order interactions between nodes. However, training GNNs without protection may leak sensitive…

Machine Learning · Computer Science 2026-02-10 Wen Xu , Zhetao Li , Yong Xiao , Pengpeng Qiao , Mianxiong Dong , Kaoru Ota

Homomorphic Encryption (HE) draws a significant attention as a privacy-preserving way for cloud computing because it allows computation on encrypted messages called ciphertexts. Among numerous HE schemes proposed, HE for Arithmetic of…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-07-15 Wonkyung Jung , Eojin Lee , Sangpyo Kim , Keewoo Lee , Namhoon Kim , Chohong Min , Jung Hee Cheon , Jung Ho Ahn

Artificial intelligence (AI) increasingly powers sensitive applications in domains such as healthcare and finance, relying on both linear operations (e.g., matrix multiplications in large language models) and non-linear operations (e.g.,…

Fully Homomorphic Encryption (FHE) enables privacy-preserving Transformer inference, but long-sequence encrypted Transformers quickly exceed single-GPU memory capacity because encoded weights are already large and encrypted activations grow…

Cryptography and Security · Computer Science 2026-04-07 Zhaoting Gong , Ran Ran , Fan Yao , Wujie Wen

Fully homomorphic encryption (FHE) is one of the prospective tools for privacypreserving machine learning (PPML), and several PPML models have been proposed based on various FHE schemes and approaches. Although the FHE schemes are known as…

Privacy-preserving machine learning (PPML) is an emerging topic to handle secure machine learning inference over sensitive data in untrusted environments. Fully homomorphic encryption (FHE) enables computation directly on encrypted data on…

Cryptography and Security · Computer Science 2025-10-24 Yu Hin Chan , Hao Yang , Shiyu Shen , Xingyu Fan , Shengzhe Lyu , Patrick S. Y. Hung , Ray C. C. Cheung

Recently, deep learning as a service (DLaaS) has emerged as a promising way to facilitate the employment of deep neural networks (DNNs) for various purposes. However, using DLaaS also causes potential privacy leakage from both clients and…

Cryptography and Security · Computer Science 2020-11-13 Peichen Xie , Bingzhe Wu , Guangyu Sun

Fully homomorphic encryption (FHE) is an encryption method that allows to perform computation on encrypted data, without decryption. FHE preserves the privacy of the users of online services that handle sensitive data, such as health data,…

Machine Learning · Computer Science 2023-02-23 Andrei Stoian , Jordan Frery , Roman Bredehoft , Luis Montero , Celia Kherfallah , Benoit Chevallier-Mames

Generalized linear mixed-effects models in the context of genome-wide association studies (GWAS) represent a formidable computational challenge: the solution of millions of correlated generalized least-squares problems, and the processing…

Mathematical Software · Computer Science 2013-05-02 Diego Fabregat-Traver , Yurii Aulchenko , Paolo Bientinesi

Homomorphic encryption (HE) is pivotal for secure computation on encrypted data, crucial in privacy-preserving data analysis. However, efficiently processing high-dimensional data in HE, especially for machine learning and statistical…

Cryptography and Security · Computer Science 2024-06-17 Joon Soo Yoo , Baek Kyung Song , Tae Min Ahn , Ji Won Heo , Ji Won Yoon
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