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Interferometric scattering microscopy is a powerful technique that enables various applications, such as mass photometry and particle tracking. Here we present a numerical toolbox to simulate images obtained in interferometric scattering,…

Intravoxel incoherent motion (IVIM) imaging allows contrast-agent free in vivo perfusion quantification with magnetic resonance imaging (MRI). However, its use is limited by typically low accuracy due to low signal-to-noise ratio (SNR) at…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Lin Zhang , Valery Vishnevskiy , Andras Jakab , Orcun Goksel

In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-shifting interferometer, built onto a phase-contrast microscope, with white-light illumination. As one of the most sensitive quantitative phase…

Optics · Physics 2020-12-17 Xi Chen , Mikhail E. Kandel , Gabriel Popescu

Nonlinear quantum metrology schemes can lead to faster than Heisenberg limited scalings for the measurement uncertainty. We study a Michelson interferometer embedded in a Kerr medium [Luis and Rivas, Phys. Rev. A 92, 022104 (2015)] that…

Quantum Physics · Physics 2021-12-07 Bijoy John Mathew , Anil Shaji

A new tool providing material contrast control in scanning electron microscopy (SEM) is demonstrated. The approach is based on deep-UV illumination during SEM imaging and delivers a novel material based contrast as well as higher resolution…

Instrumentation and Detectors · Physics 2016-04-07 Gediminas Seniutinas , Armandas Balcytis , Saulius Juodkazis

Microwave photonics (MWP), harnessing the tremendous bandwidth of light to generate, process and measure wideband microwave signals, are poised to spark a new revolution for the information and communication fields. Within the past decade,…

Applied Physics · Physics 2022-02-24 Yuansheng Tao , Fenghe Yang , Zihan Tao , Lin Chang , Haowen Shu , Ming Jin , Yan Zhou , Zhangfeng Ge , Xingjun Wang

Double-slit electron interferometers, fabricated in high mobility two-dimensional electron gas (2DEG), proved to be very powerful tools in studying coherent wave-like phenomena in mesoscopic systems. However, they suffer from small fringe…

Mesoscale and Nanoscale Physics · Physics 2009-11-10 Yang Ji , Yunchul Chung , D. Sprinzak , M. Heiblum , D. Mahalu , Hadas Shtrikman

The hybrid interferometer integrating an optical parametric amplifier and a beam splitter has the potential to outperform the SU(1,1) interferometer. However, photon loss remains a critical limitation for practical implementation. To…

Quantum Physics · Physics 2025-10-21 Qisi Zhou , Tao Jiang , Qingqian Kang , Teng Zhao , Xin Su , Cunjin Liu , Liyun Hu

We demonstrate chip-scale flat-top filters at near-infrared wavelengths using negative index photonic crystal based Mach Zehnder interferometers. Supported by full three-dimensional numerical simulations, we experimentally demonstrate a new…

Optics · Physics 2015-06-03 S. Kocaman , M. S. Aras , N. C. Panoiu , M. Lu , C. W. Wong

This work discusses the possibility of using two-mode squeezed light to improve the performance of existing sensor technology with the focus on its miniaturization under realistic losses. Therefore, we analyze a system consisting of a part…

Immunofluorescent (IF) imaging is crucial for visualizing biomarker expressions, cell morphology and assessing the effects of drug treatments on sub-cellular components. IF imaging needs extra staining process and often requiring cell…

The transmission electron microscope facilitates the highest-resolution imaging of any instrument ever created, and its limiting factor is no longer spatial resolution but dose efficiency. Low electron doses avoid sample damage but produce…

Machine Learning · Computer Science 2026-05-08 Georgia Channing , Debora Keller , Marta D. Rossell , Philip Torr , Stig Helveg , Henrik Eliasson

Microscopy has been key to tremendous advances in science, technology, and medicine, revealing structure and dynamics across time and length scales. However, combining high spatial and temporal resolution in a non-invasive, label-free…

A design of an efficient monochromatic electron source for Inverse Photoemission Spectroscopy (IPES) apparatus is described. The electron source consists of a BaO cathode, a focus electrostatic lens, a hemispherical deflection monochromator…

Instrumentation and Detectors · Physics 2014-01-13 Geng Dongping , Yang Yingguo , Liu Shuhu , Hong Caihao , Gao Xingyu

We report on the design of an all-mirror wavefront-division interferometer capable of spectroscopic studies across multiple spectral ranges$\unicode{x2013}$from the plasma frequencies of metals to terahertz wavelengths and beyond. The…

Programmable linear optical interferometers are promising for classical and quantum applications. Their integrated design makes it possible to create more scalable and stable devices. To use them in practice, one has to reconstruct the…

Quantum Physics · Physics 2024-01-12 B. I. Bantysh , A. Yu. Chernyavskiy , S. A. Fldzhyan , Yu. I. Bogdanov

Recently, Rydberg atom has emerged as an attractive choice to realize quantum sensing of low-frequency electric field. The progress so far has mostly utilized the intensity and phase changes in probe laser and the corresponding detection…

Atomic Physics · Physics 2026-03-11 Ding Wang , Shenchao Jin , Xiayang Fan , Hongjing Li , Jiatian Liu , Jingzheng Huang , Guihua Zeng , Yuan Sun

Imaging based on the induced coherence effect makes use of photon pairs to obtain information of an object without detecting the light that probes it. While one photon illuminates the object, only its partner is detected, so no measurement…

We study theoretically electronic Mach-Zehnder interferometers built from integer quantum Hall edge states, showing that the results of recent experiments can be understood in terms of multiparticle interference effects. These experiments…

Strongly Correlated Electrons · Physics 2010-05-27 D. L. Kovrizhin , J. T. Chalker

We introduce a phase imaging mechanism for scanning transmission electron microscopy that exploits the complementary intensity changes of transmitted disks at different scattering angles. For scanning transmission electron microscopy, this…

Instrumentation and Detectors · Physics 2023-07-06 Binbin Wang , David W. McComb