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Related papers: Model-Based Reinforcement Learning for Sepsis Trea…

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We develop a deep learning approach to predicting a set of ventilator parameters for a mechanically ventilated septic patient using a long and short term memory (LSTM) recurrent neural network (RNN) model. We focus on short-term predictions…

Quantitative Methods · Quantitative Biology 2022-02-23 Zhijun Zeng , Zhen Hou , Ting Li , Lei Deng , Jianguo Hou , Xinran Huang , Jun Li , Meirou Sun , Yunhan Wang , Qiyu Wu , Wenhao Zheng , Hua Jiang , Qi Wang

Reinforcement learning (RL), a common tool in decision making, learns control policies from various experiences based on the associated cumulative return/rewards without treating them differently. Humans, on the contrary, often learn to…

Machine Learning · Computer Science 2025-11-25 Mingkang Wu , Devin White , Vernon Lawhern , Nicholas R. Waytowich , Yongcan Cao

Reinforcement Learning (RL) is a method for learning decision-making tasks that could enable robots to learn and adapt to their situation on-line. For an RL algorithm to be practical for robotic control tasks, it must learn in very few…

Artificial Intelligence · Computer Science 2015-03-19 Todd Hester , Michael Quinlan , Peter Stone

In this study, we discuss how reinforcement learning (RL) provides an effective and efficient framework for solving sociohydrology problems. The efficacy of RL for these types of problems is evident because of its ability to update policies…

Machine Learning · Computer Science 2024-06-03 Tirthankar Roy , Shivendra Srivastava , Beichen Zhang

This paper proposes a novel formulation for reinforcement learning (RL) with large language models, explaining why and under what conditions the true sequence-level reward can be optimized via a surrogate token-level objective in policy…

Machine Learning · Computer Science 2025-12-04 Chujie Zheng , Kai Dang , Bowen Yu , Mingze Li , Huiqiang Jiang , Junrong Lin , Yuqiong Liu , Hao Lin , Chencan Wu , Feng Hu , An Yang , Jingren Zhou , Junyang Lin

Recent statistical and reinforcement learning methods have significantly advanced patient care strategies. However, these approaches face substantial challenges in high-stakes contexts, including missing data, inherent stochasticity, and…

Machine Learning · Computer Science 2024-04-02 Harsh Parikh , Quinn Lanners , Zade Akras , Sahar F. Zafar , M. Brandon Westover , Cynthia Rudin , Alexander Volfovsky

Many organisms and cell types, from bacteria to cancer cells, exhibit a remarkable ability to adapt to fluctuating environments. Additionally, cells can leverage a memory of past environments to better survive previously-encountered…

Machine Learning · Computer Science 2025-01-29 Josiah C. Kratz , Jacob Adamczyk

Characterizing a patient's progression through stages of sepsis is critical for enabling risk stratification and adaptive, personalized treatment. However, commonly used sepsis diagnostic criteria fail to account for significant underlying…

Appropriate medication dosages in the intensive care unit (ICU) are critical for patient survival. Heparin, used to treat thrombosis and inhibit blood clotting in the ICU, requires careful administration due to its complexity and…

Machine Learning · Computer Science 2025-12-09 Yooseok Lim , Inbeom Park , Sujee Lee

This study proposes the use of Machine Learning models to predict the early onset of sepsis using deidentified clinical data from Montefiore Medical Center in Bronx, NY, USA. A supervised learning approach was adopted, wherein an XGBoost…

Reinforcement Learning (RL) based methods have seen their paramount successes in solving serial decision-making and control problems in recent years. For conventional RL formulations, Markov Decision Process (MDP) and state-action-value…

Machine Learning · Computer Science 2020-06-09 Ziyao Zhang , Liang Ma , Kin K. Leung , Konstantinos Poularakis , Mudhakar Srivatsa

Balancing exploration and exploitation is crucial in reinforcement learning (RL). In this paper, we study model-based posterior sampling for reinforcement learning (PSRL) in continuous state-action spaces theoretically and empirically.…

Machine Learning · Computer Science 2021-11-18 Ying Fan , Yifei Ming

Why do reinforcement learning (RL) policies fail or succeed? This is a challenging question due to the complex, high-dimensional nature of agent-environment interactions. In this work, we take a causal perspective on explaining the behavior…

Machine Learning · Statistics 2025-07-22 Armin Kekić , Jan Schneider , Dieter Büchler , Bernhard Schölkopf , Michel Besserve

Reinforcement learning has long struggled with poor sample efficiency. One promising approach to mitigate this problem is leveraging group-invariant Markov Decision Processes ($G$-invariant MDPs). Existing works in this direction have…

Machine Learning · Computer Science 2026-05-25 Shuai Zhen , Yifan Zhang , Yuling Wang , Yanhua Yu

The prognosis for patients with epithelial ovarian cancer remains dismal despite improvements in survival for other cancers. Treatment involves multiple lines of chemotherapy and becomes increasingly heterogeneous after first-line therapy.…

Machine Learning · Computer Science 2021-10-25 Brian Murphy , Mustafa Nasir-Moin , Grace von Oiste , Viola Chen , Howard A Riina , Douglas Kondziolka , Eric K Oermann

The use of reinforcement learning (RL) methods to support health behavior change via personalized and just-in-time adaptive interventions is of significant interest to health and behavioral science researchers focused on problems such as…

Machine Learning · Computer Science 2025-07-08 Karine Karine , Benjamin M. Marlin

Objective: Epilepsy is one of the most prevalent neurological diseases among humans and can lead to severe brain injuries, strokes, and brain tumors. Early detection of seizures can help to mitigate injuries, and can be used to aid the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-20 Theekshana Dissanayake , Tharindu Fernando , Simon Denman , Sridha Sridharan , Clinton Fookes

Despite the many recent advances in reinforcement learning (RL), the question of learning policies that robustly satisfy state constraints under unknown disturbances remains open. In this paper, we offer a new perspective on achieving…

Machine Learning · Computer Science 2025-12-23 Pierre-François Massiani , Alexander von Rohr , Lukas Haverbeck , Sebastian Trimpe

Reinforcement learning (RL) has been widely applied in recommendation systems due to its potential in optimizing the long-term engagement of users. From the perspective of RL, recommendation can be formulated as a Markov decision process…

Information Retrieval · Computer Science 2023-10-26 Chengpeng Li , Zhengyi Yang , Jizhi Zhang , Jiancan Wu , Dingxian Wang , Xiangnan He , Xiang Wang

We consider the problem of predicting how the likelihood of an outcome of interest for a patient changes over time as we observe more of the patient data. To solve this problem, we propose a supervised contrastive learning framework that…

Machine Learning · Computer Science 2024-04-16 Shahriar Noroozizadeh , Jeremy C. Weiss , George H. Chen