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Related papers: Model-Based Reinforcement Learning for Sepsis Trea…

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This paper investigates search in model-based reinforcement learning (RL). Conventional wisdom holds that long-term predictions and compounding errors are the primary obstacles for model-based RL. We challenge this view, showing that search…

Machine Learning · Computer Science 2026-05-25 Wei-Di Chang , Mikael Henaff , Brandon Amos , Gregory Dudek , Scott Fujimoto

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

Neurons and Cognition · Quantitative Biology 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor

Sepsis accounts for more than 50% of hospital deaths, and the associated cost ranks the highest among hospital admissions in the US. Improved understanding of disease states, severity, and clinical markers has the potential to significantly…

Quantitative Methods · Quantitative Biology 2022-10-11 Chih-Hao Fang , Vikram Ravindra , Salma Akhter , Mohammad Adibuzzaman , Paul Griffin , Shankar Subramaniam , Ananth Grama

Reinforcement learning (RL) is a powerful approach for robot learning. However, model-free RL (MFRL) requires a large number of environment interactions to learn successful control policies. This is due to the noisy RL training updates and…

Robotics · Computer Science 2025-02-28 Maria Krinner , Elie Aljalbout , Angel Romero , Davide Scaramuzza

Machine learning (ML) has revolutionized medical prognostics by integrating advanced algorithms with clinical data to enhance disease prediction, risk assessment, and patient outcome forecasting. This comprehensive review critically…

Machine Learning · Computer Science 2024-08-06 Michael Fascia

Imagine a patient in critical condition. What and when should be measured to forecast detrimental events, especially under the budget constraints? We answer this question by deep reinforcement learning (RL) that jointly minimizes the…

Machine Learning · Computer Science 2019-06-11 Chun-Hao Chang , Mingjie Mai , Anna Goldenberg

Owe to the recent advancements in Artificial Intelligence especially deep learning, many data-driven decision support systems have been implemented to facilitate medical doctors in delivering personalized care. We focus on the deep…

Machine Learning · Computer Science 2019-07-24 Siqi Liu , Kee Yuan Ngiam , Mengling Feng

Real-world reinforcement learning (RL) problems often demand that agents behave safely by obeying a set of designed constraints. We address the challenge of safe RL by coupling a safety guide based on model predictive control (MPC) with a…

Machine Learning · Computer Science 2022-03-30 Samuel Pfrommer , Tanmay Gautam , Alec Zhou , Somayeh Sojoudi

While large language models hold promise for complex medical applications, their development is hindered by the scarcity of high-quality reasoning data. To address this issue, existing approaches typically distill chain-of-thought reasoning…

Machine Learning · Computer Science 2026-04-14 Haolin Li , Shuyang Jiang , Ruipeng Zhang , Jiangchao Yao , Ya Zhang , Yanfeng Wang

With a mortality rate of 5.4 million lives worldwide every year and a healthcare cost of more than 16 billion dollars in the USA alone, sepsis is one of the leading causes of hospital mortality and an increasing concern in the ageing…

Machine Learning · Computer Science 2021-05-12 Margherita Rosnati , Vincent Fortuin

Reinforcement learning (RL) is rapidly reaching and surpassing human-level control capabilities. However, state-of-the-art RL algorithms often require timesteps and reaction times significantly faster than human capabilities, which is…

Machine Learning · Computer Science 2025-07-29 Devdhar Patel , Hava Siegelmann

Reinforcement learning (RL) marks a fundamental shift in how artificial intelligence is applied in healthcare. Instead of merely predicting outcomes, RL actively decides interventions with long term goals. Unlike traditional models that…

Machine Learning · Computer Science 2025-09-01 Dilruk Perera , Gousia Habib , Qianyi Xu , Daniel J. Tan , Kai He , Erik Cambria , Mengling Feng

Medical treatments often involve a sequence of decisions, each informed by previous outcomes. This process closely aligns with reinforcement learning (RL), a framework for optimizing sequential decisions to maximize cumulative rewards under…

Machine Learning · Computer Science 2024-10-15 Ali Shirali , Alexander Schubert , Ahmed Alaa

This study addresses a gap in the utilization of Reinforcement Learning (RL) and Machine Learning (ML) techniques in solving the Stochastic Vehicle Routing Problem (SVRP) that involves the challenging task of optimizing vehicle routes under…

Artificial Intelligence · Computer Science 2023-11-15 Zangir Iklassov , Ikboljon Sobirov , Ruben Solozabal , Martin Takac

Deep reinforcement learning (RL) is a powerful approach to complex decision making. However, one issue that limits its practical application is its brittleness, sometimes failing to train in the presence of small changes in the environment.…

Machine Learning · Computer Science 2025-01-27 Jung-Hoon Cho , Vindula Jayawardana , Sirui Li , Cathy Wu

Purpose: In high-dose-rate (HDR) prostate brachytherapy procedures, the pattern of needle placement solely relies on physician experience. We investigated the feasibility of using reinforcement learning (RL) to provide needle positions and…

Medical Physics · Physics 2025-06-12 Tonghe Wang , Yining Feng , Xiaofeng Yang

Standard reinforcement learning (RL) aims to find an optimal policy that identifies the best action for each state. However, in healthcare settings, many actions may be near-equivalent with respect to the reward (e.g., survival). We…

Machine Learning · Computer Science 2020-07-27 Shengpu Tang , Aditya Modi , Michael W. Sjoding , Jenna Wiens

Constrained Reinforcement Learning has been employed to enforce safety constraints on policy through the use of expected cost constraints. The key challenge is in handling expected cost accumulated using the policy and not just in a single…

Machine Learning · Computer Science 2024-01-17 Hao Jiang , Tien Mai , Pradeep Varakantham , Minh Huy Hoang

Background Sepsis is one of the most life-threatening circumstances for critically ill patients in the US, while a standardized criteria for sepsis identification is still under development. Disparities in social determinants of sepsis…

Machine Learning · Computer Science 2021-12-16 Hanyin Wang , Yikuan Li , Andrew Naidech , Yuan Luo

Offline reinforcement learning (RL) aims to learn an optimal policy from pre-collected data. However, it faces challenges of distributional shift, where the learned policy may encounter unseen scenarios not covered in the offline data.…

Machine Learning · Computer Science 2025-05-27 Jin Zhu , Xin Zhou , Jiaang Yao , Gholamali Aminian , Omar Rivasplata , Simon Little , Lexin Li , Chengchun Shi
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