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Related papers: Model-Based Reinforcement Learning for Sepsis Trea…

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The timeliness of detection of a sepsis event in progress is a crucial factor in the outcome for the patient. Machine learning models built from data in electronic health records can be used as an effective tool for improving this…

We study constrained reinforcement learning (CRL) from a novel perspective by setting constraints directly on state density functions, rather than the value functions considered by previous works. State density has a clear physical and…

Machine Learning · Computer Science 2021-06-25 Zengyi Qin , Yuxiao Chen , Chuchu Fan

Model-free reinforcement learning (RL) is inherently a reactive method, operating under the assumption that it starts with no prior knowledge of the system and entirely depends on trial-and-error for learning. This approach faces several…

There is increasing interest in data-driven approaches for recommending optimal treatment strategies in many chronic disease management and critical care applications. Reinforcement learning methods are well-suited to this sequential…

Machine Learning · Computer Science 2023-06-14 Milashini Nambiar , Supriyo Ghosh , Priscilla Ong , Yu En Chan , Yong Mong Bee , Pavitra Krishnaswamy

Reinforcement learning (RL) in healthcare has had mixed results, with reward sparsity, unreliable off-policy evaluation, and deployment-simulation gap as recurring failure modes. We argue that chronic disease management is structurally a…

Machine Learning · Computer Science 2026-05-12 Prabhjot Singh , Abhishek Gupta , Chris Betz , Abe Flansburg , Brett Ives , Sudeep Lama , Jung Hoon Son

Many real-world applications of reinforcement learning (RL) require making decisions in continuous action environments. In particular, determining the optimal dose level plays a vital role in developing medical treatment regimes. One…

Machine Learning · Statistics 2023-10-03 Yuhan Li , Wenzhuo Zhou , Ruoqing Zhu

Recent years have witnessed significant progresses in deep Reinforcement Learning (RL). Empowered with large scale neural networks, carefully designed architectures, novel training algorithms and massively parallel computing devices,…

Machine Learning · Computer Science 2018-04-23 Chiyuan Zhang , Oriol Vinyals , Remi Munos , Samy Bengio

Over the last decade, the use of machine learning (ML) approaches in medicinal applications has increased manifold. Most of these approaches are based on deep learning, which aims to learn representations from grid data (like medical…

Image and Video Processing · Electrical Eng. & Systems 2025-02-24 Maha Ezzelarab , Midhila Madhusoodanan , Shrimanti Ghosh , Geetika Vadali , Jacob Jaremko , Abhilash Hareendranathan

Evidence-based or data-driven dynamic treatment regimes are essential for personalized medicine, which can benefit from offline reinforcement learning (RL). Although massive healthcare data are available across medical institutions, they…

Machine Learning · Statistics 2024-01-30 Doudou Zhou , Yufeng Zhang , Aaron Sonabend-W , Zhaoran Wang , Junwei Lu , Tianxi Cai

Compared with model-based control and optimization methods, reinforcement learning (RL) provides a data-driven, learning-based framework to formulate and solve sequential decision-making problems. The RL framework has become promising due…

Systems and Control · Electrical Eng. & Systems 2024-07-29 Pouria Razzaghi , Amin Tabrizian , Wei Guo , Shulu Chen , Abenezer Taye , Ellis Thompson , Alexis Bregeon , Ali Baheri , Peng Wei

Hypotension in critical care settings is a life-threatening emergency that must be recognized and treated early. While fluid bolus therapy and vasopressors are common treatments, it is often unclear which interventions to give, in what…

Machine Learning · Statistics 2020-01-13 Joseph Futoma , Muhammad A. Masood , Finale Doshi-Velez

The risks and perils of overfitting in machine learning are well known. However most of the treatment of this, including diagnostic tools and remedies, was developed for the supervised learning case. In this work, we aim to offer new…

Machine Learning · Computer Science 2018-06-26 Amy Zhang , Nicolas Ballas , Joelle Pineau

Adoption of machine learning (ML)-enabled cyber-physical systems (CPS) are becoming prevalent in various sectors of modern society such as transportation, industrial, and power grids. Recent studies in deep reinforcement learning (DRL) have…

Machine Learning · Computer Science 2020-07-15 Kai Liang Tan , Yasaman Esfandiari , Xian Yeow Lee , Aakanksha , Soumik Sarkar

Pain management in intensive care usually involves complex trade-offs, since both inadequate and excessive treatment can compromise patient safety. Prior work on reinforcement learning for sedation and analgesia has explored how to optimize…

Machine Learning · Computer Science 2026-05-19 Joel Romero-Hernandez , Oscar Camara

Recommender systems have been widely applied in different real-life scenarios to help us find useful information. In particular, Reinforcement Learning (RL) based recommender systems have become an emerging research topic in recent years,…

Information Retrieval · Computer Science 2023-06-13 Yuanguo Lin , Yong Liu , Fan Lin , Lixin Zou , Pengcheng Wu , Wenhua Zeng , Huanhuan Chen , Chunyan Miao

This paper proposes tackling safety-critical stochastic Reinforcement Learning (RL) tasks with a sample-based, model-based approach. At the core of the method lies a Model Predictive Control (MPC) scheme that acts as function approximation,…

Systems and Control · Electrical Eng. & Systems 2025-07-30 Filippo Airaldi , Bart De Schutter , Azita Dabiri

Dynamic Treatment Regimes (DTRs) provide a systematic approach for making sequential treatment decisions that adapt to individual patient characteristics, particularly in clinical contexts where survival outcomes are of interest.…

Machine Learning · Computer Science 2025-03-11 Animesh Kumar Paul , Russell Greiner

Driven by the key challenges of cell therapy manufacturing, including high complexity, high uncertainty, and very limited process observations, we propose a hybrid model-based reinforcement learning (RL) to efficiently guide process…

Systems and Control · Electrical Eng. & Systems 2022-01-27 Hua Zheng , Wei Xie , Keqi Wang , Zheng Li

Care-giving and assistive robotics, driven by advancements in AI, offer promising solutions to meet the growing demand for care, particularly in the context of increasing numbers of individuals requiring assistance. This creates a pressing…

Robotics · Computer Science 2024-05-14 Andrii Tytarenko

The large-scale integration of intermittent renewable energy resources introduces increased uncertainty and volatility to the supply side of power systems, thereby complicating system operation and control. Recently, data-driven approaches,…

Systems and Control · Electrical Eng. & Systems 2024-07-02 Peipei Yu , Zhenyi Wang , Hongcai Zhang , Yonghua Song