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Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

We present an epidemiological model for vector-borne diseases that includes within-host viral load and antibody dynamics using structured transport equations. By incorporating the internal dynamics into the infected and recovered host…

Analysis of PDEs · Mathematics 2026-05-26 Paulo Amorim , Maria Soledad Aronna , Debora de Oliveira Medeiros

Stochastic difference equations and a stochastic partial differential equation (SPDE) are simultaneously derived for the time-dependent neutron angular density in a general three-dimensional medium where the neutron angular density is a…

Numerical Analysis · Mathematics 2010-04-16 Edward J. Allen

Dengue remains a major global public health concern due to its high mortality and economic burden. Mathematical modeling is essential to understand its transmission mechanisms and for evaluating intervention strategies. In this paper, we…

Populations and Evolution · Quantitative Biology 2026-04-28 Sourav Banerjee , Thomas Götz , Satyananda Panda

Multivariate count time series models are an important tool for the analysis and prediction of infectious disease spread. We consider the endemic-epidemic framework, an autoregressive model class for infectious disease surveillance counts,…

Applications · Statistics 2020-03-16 Johannes Bracher , Leonhard Held

We investigate a time-dependent spatial vector-host epidemic model with non-coincident domains for the vector and host populations. The host population resides in small non-overlapping sub-regions, while the vector population resides…

Analysis of PDEs · Mathematics 2018-09-12 W. E. Fitzgibbon , J. J. Morgan , Glenn F. Webb , Yixiang Wu

It is possible to model vector-borne infection using the classical Ross-Macdonald model. This attempt, however fails in several respects. First, using measured (or estimated) parameters, the model predicts a much greater number of cases…

Defective interfering particles (DIPs) are virus-like particles that occur naturally during virus infections. These particles are defective, lacking essential genetic materials for replication, but they can interact with the wild-type virus…

Quantitative Methods · Quantitative Biology 2024-02-16 Qiantong Liang , Johnny Yang , Wai-Tong Louis Fan , Wing-Cheong Lo

The impact of spatial structure on the spread of an epidemic is an important issue in the propagation of infectious diseases. Recent studies, both deterministic and stochastic, have made it possible to understand the importance of the…

Probability · Mathematics 2023-01-09 Alphonse Emakoua

We propose an SEIR model for the populations and an SEI model for the vector to describe the transmission dynamics of a four-strain model with both primary and secondary dengue infections. In order to accomplish this, we propose and obtain…

Populations and Evolution · Quantitative Biology 2014-06-18 Raul Isea

Dengue is a vector-borne disease and 40% of world population is at risk. Dengue transcends international borders and can be found in tropical and subtropical regions around the world, predominantly in urban and semi-urban areas. A model for…

Populations and Evolution · Quantitative Biology 2016-08-10 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres , Ana Clara Silva , Carla Sousa , Cláudia Conceição

A model with six mutually-exclusive compartments related to Dengue disease is presented. In this model there are three vector control tools: insecticides (larvicide and adulticide) and mechanical control. The problem is studied using an…

Optimization and Control · Mathematics 2012-07-10 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

We develop a stochastic two-patch epidemic model with nonlinear recidivism to investigate infectious disease dynamics in heterogeneous populations. Extending a deterministic framework, we introduce stochasticity to account for random…

Populations and Evolution · Quantitative Biology 2024-05-21 Juan G. Calvo , Mario I. Simoy , Juan P. Aparicio , José E. Chacón , Fabio Sanchez

Dengue fever is a flu-like illness spread by the bite of an infected mosquito which is fast emerging as a major health problem. Timely and cost effective diagnosis using clinical and laboratory features would reduce the mortality rates…

Machine Learning · Computer Science 2013-06-06 M. Naresh Kumar

We approach the development of models and control strategies of susceptible-infected-susceptible (SIS) epidemic processes from the perspective of marked temporal point processes and stochastic optimal control of stochastic differential…

Optimization and Control · Mathematics 2018-12-04 Lars Lorch , Abir De , Samir Bhatt , William Trouleau , Utkarsh Upadhyay , Manuel Gomez-Rodriguez

Dynamical systems that are subject to continuous uncertain fluctuations can be modelled using Stochastic Differential Equations (SDEs). Controlling such system results in solving path constrained SDEs. Broadly, these problems fall under the…

Optimization and Control · Mathematics 2023-06-16 Sumit Suthar , Soumyendu Raha

Mathematical models are vital interpretive and predictive tools used to assist in the understanding of cell migration. There are typically two approaches to modelling cell migration: either micro-scale, discrete or macro-scale, continuum.…

Cell Behavior · Quantitative Biology 2018-08-16 Enrico Gavagnin , Christian A. Yates

We present a simple model for the spread of an infection that incorporates spatial variability in population density. Starting from first principle considerations, we explore how a novel PDE with state-dependent diffusion can be obtained.…

Populations and Evolution · Quantitative Biology 2021-10-28 A. Vaziry , T. Kolokolnikov , P. G. Kevrekidis

Physical models with uncertain inputs are commonly represented as parametric partial differential equations (PDEs). That is, PDEs with inputs that are expressed as functions of parameters with an associated probability distribution.…

Numerical Analysis · Mathematics 2023-05-15 Benjamin M. Kent , Catherine E. Powell , David J. Silvester , Małgorzata J. Zimoń
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