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The incidence of Dengue epidemiologic disease has grown in recent decades. In this paper an application of optimal control in Dengue epidemics is presented. The mathematical model includes the dynamic of Dengue mosquito, the affected…

Optimization and Control · Mathematics 2010-09-03 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

An epidemic multi-strain model with temporary cross-immunity shows chaos, even in a previously unexpected parameter region. Especially dengue fever models with strong enhanced infectivity on secondary infection have previously shown…

Chaotic Dynamics · Physics 2007-06-25 Maíra Aguiar , Nico Stollenwerk

Stemming from the stochastic Lotka-Volterra or predator-prey equations, this work aims to model the spatial inhomogeneity by using stochastic partial differential equations (SPDEs). Compared to the classical models, the SPDE model is more…

Dynamical Systems · Mathematics 2019-11-21 N. N. Nhu , G. Yin

Differential equations (DEs) are commonly used to describe dynamic systems evolving in one (ordinary differential equations or ODEs) or in more than one dimensions (partial differential equations or PDEs). In real data applications the…

Methodology · Statistics 2013-11-25 Gianluca Frasso , Jonathan Jaeger , Philippe Lambert

As offered by the World Health Organisation (WHO), close to half of the population in the world's resides in dengue-risk zones. Dengue viruses are transmitted to individuals by Aedes mosquito species infected bite (Ae. Albopictus of Ae.…

Populations and Evolution · Quantitative Biology 2025-03-12 Burcu Gürbüz , Aytül Gökçe , Segun I. Oke , Michael O. Adeniyi , Mayowa M. Ojo

Spatial reaction-diffusion models have been employed to describe many emergent phenomena in biological systems. The modelling technique most commonly adopted in the literature implements systems of partial differential equations (PDEs),…

Quantitative Methods · Quantitative Biology 2015-10-05 Christian A. Yates , Mark B. Flegg

Dengue is a vector-borne disease transmitted by the mosquito Aedes aegypti. It has been observed that its incidence is strongly influenced by temperature and other abiotic factors like rainfall and humidity. In this work we compare the…

Populations and Evolution · Quantitative Biology 2016-05-23 Emilene Pliego Pliego , Jorge Velazquez-Castro , Andres Fraguela-Collar

Dengue is an infectious disease which poses significant socioeconomic and disease burden in many tropical and subtropical regions of the world. This work aims to provide additional insight into the association between dengue and climate in…

Applications · Statistics 2025-06-30 Stephen Jun Villejo , Sara Martino , Janine Illian

We consider compartmental models in epidemiology. For the study of the divergence of the stochastic model from its corresponding deterministic limit (i.e., the solution of an ODE) for long time horizon, a large deviations principle suggests…

Probability · Mathematics 2015-01-16 Peter Kratz , Etienne Pardoux , Brice Samegni Kepgnou

Vector-borne diseases arise from the coupled dynamics of human mobility and mosquito ecology, producing outbreaks shaped by both spatial distributions and temporal patterns of movement. Here we develop a coarse-grained hub--leaf reduction…

Populations and Evolution · Quantitative Biology 2025-08-29 Bibandhan Poudyal , Gourab Ghoshal

Metapopulation (multipatch) models are widely used to study the patterns of spatial spread of epidemics. In this paper we study the impact of inter-patch connection weights on the predictions of these models. We contrast arbitrary, uniform…

Applications · Statistics 2013-08-26 Marta Sarzynska , Oyita Udiani , Na Zhang

The objective of this study was to characterize the spatiotemporal dynamics and climatic and social-ecological risk factors associated with the largest dengue epidemic to date in Machala, Ecuador, to inform the development of a dengue EWS.…

Stochastic differential equations (SDEs) provide a natural framework for modelling intrinsic stochasticity inherent in many continuous-time physical processes. When such processes are observed in multiple individuals or experimental units,…

Computation · Statistics 2016-05-19 Gavin A. Whitaker , Andrew Golightly , Richard J. Boys , Chris Sherlock

Dengue fever poses a persistent public health challenge in rapidly urbanizing Indian cities such as Ahmedabad, where spatial heterogeneity and seasonal variability complicate forecasting and control. In this study, we develop a data-driven…

Populations and Evolution · Quantitative Biology 2026-05-19 Sourav Roy , Rajendra Gadhavi , Bhavin Solanki , Chirag Shah , Raj C. Sharma , Indrajit Ghosh

We study an individual-based stochastic spatial epidemic model where the number of locations and the number of individuals at each location both grow to infinity. Each individual is associated with a random infection-age dependent…

Probability · Mathematics 2025-10-21 Guodong Pang , Etienne Pardoux

Dengue is a mosquito-borne disease that threatens more than half of the world's population. Despite being endemic to over 100 countries, government-led efforts and mechanisms to timely identify and track the emergence of new infections are…

Applications · Statistics 2016-12-09 Shihao Yang , S. C. Kou , Fred Lu , John S. Brownstein , Nicholas Brooke , Mauricio Santillana

Dengue virus has caused major problems for public health officials for decades in tropical and subtropical countries. We construct a compartmental model that includes the risk of hospitalization and its impact on public health policies. The…

Populations and Evolution · Quantitative Biology 2019-08-09 Fabio Sanchez , Jorge Arroyo-Esquivel , Paola Vasquez

It is common to use a compartmental, fluid model described by a system of ordinary differential equations (ODEs) to model disease spread. In addition to their simplicity, these models are also the mean-field approximations of more accurate…

Probability · Mathematics 2016-04-15 Benjamin Armbruster , Ekkehard Beck

The relationship between epidemiology, mathematical modeling and computational tools allows to build and test theories on the development and battling of a disease. This PhD thesis is motivated by the study of epidemiological models applied…

Optimization and Control · Mathematics 2014-01-30 Helena Sofia Rodrigues

Delayed processes are ubiquitous in biological systems and are often characterized by delay differential equations (DDEs) and their extension to include stochastic effects. DDEs do not explicitly incorporate intermediate states associated…

Quantitative Methods · Quantitative Biology 2016-09-28 Jingchen Feng , Stuart Sevier , Bin Huang , Dongya Jia , Herbert Levine