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Monte Carlo-transport codes are designed to simulate the complex neutron transport physics associated with nuclear systems. These codes are tasked with simulating phenomena such as temperature effects on cross-sections, thermo-physical…

We investigated cellular distribution of a tumor-specific gadolinium chelate in 4T1 and U87 cancer cells with the goal to generate more realistic geometries for Monte Carlo simulations of radiation interaction with nanoparticles in cells.…

Medical Physics · Physics 2024-01-05 Christian Velten , Brett Bell , Wolfgang A. Tomé

Due to their sequential nature, traditional DNA synthesis methods are expensive in terms of time and resources. They also fabricate multiple copies of the same strand, introducing redundancy. This redundancy can be leveraged to enhance the…

Information Theory · Computer Science 2025-10-29 Frederik Walter , Yonatan Yehezkeally

We study the electronic properties of DNA by way of a tight-binding model applied to four particular DNA sequences. The charge transfer properties are presented in terms of localisation lengths, crudely speaking the length over which…

Genomics · Quantitative Biology 2007-05-23 Daphne Klotsa , Rudolf A. Roemer , Matthew S. Turner

We describe the formation of swift heavy ion tracks in polyethylene (PE) by combining the Monte Carlo code TREKIS, which models electronic excitation in nanometric proximity of the ion trajectory, with the molecular dynamics simulating a…

Materials Science · Physics 2024-06-12 P. Babaev , F. Akhmetov , S. Gorbunov , N. Medvedev , R. Rymzhanov , R. Voronkov , A. E. Volkov

The interaction of heavy charged particles with DNA is of interest for several areas, from hadrontherapy to aero-space industry. In this paper, a TD-DFT study on the interaction of a 4 keV proton with an isolated DNA base pair was carried…

Biological Physics · Physics 2019-05-10 R. Seraide , M. A. Bernal , G. Brunetto , U. de Giovannini , A. Rubio

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

Materials Science · Physics 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume

A simple and self-consistent approach has been proposed for simulation of the proton-induced soft error rate based on the heavy ion induced single event upset cross-section data and vice versa. The approach relies on the GEANT4 assisted…

Instrumentation and Detectors · Physics 2017-10-16 Artur M. Galimov , Regina M. Galimova , Gennady I. Zebrev

The lack of molecular-level understanding for the electronic excitation response of DNA to charged particle radiation, such as high-energy protons, remains a fundamental scientific bottleneck in advancing proton and other ion beam cancer…

Soft Condensed Matter · Physics 2023-03-17 Christopher Shepard , Dillon Yost , Yosuke Kanai

A linear Breit-Wheeler module for the code Geant4 has been developed. This allows signal-to-noise ratio calculations of linear Breit-Wheeler detection experiments to be performed within a single framework. The interaction between two photon…

Plasma Physics · Physics 2023-05-31 R. A. Watt , S. J. Rose , B. Kettle , S. P. D. Mangles

Gel electrophoresis allows to separate knotted DNA (nicked circular) of equal length according to the knot type. At low electric fields, complex knots being more compact, drift faster than simpler knots. Recent experiments have shown that…

Biological Physics · Physics 2009-11-11 C. Weber , A. Stasiak , M. Fleurant , P. De Los Rios , G. Dietler

We present the latest advances of the multiscale approach to radiation damage caused by irradiation of a tissue with energetic ions and report the most recent advances in the calculations of complex DNA damage and the effects of thermal…

Biological Physics · Physics 2015-05-19 E. Surdutovich , A. V. Yakubovich , A. V. Solov'yov

Two forms of G4-DNA, with parallel and pairwise anti-parallel strands, are studied using atomic force microscopy. The directionality of the strands affects the molecules' structural properties (different height and length) and their…

Biological Physics · Physics 2014-10-08 Gideon I. Livshits , Jamal Ghabboun , Natalia Borovok , Alexander B. Kotlyar , Danny Porath

Evolutions of Geant4 code have affected the simulation of electron backscattering with respect to previously published results. Their effects are quantified by analyzing the compatibility of the simulated electron backscattering fraction…

Electromagnetic interactions of protons and alpha particles are modeled in a form that is suitable for Monte Carlo simulation of the transport of charged particles. The differential cross section (DCS) for elastic collisions with neutral…

Nuclear Theory · Physics 2023-11-13 Francesc Salvat , Carlos Heredia

Quasi-monochromatic, high energy and highly polarized $\gamma$-ray beam sources based on Compton scattering of laser photons (LCS) on relativistic electrons have developed for the last few decades as established instruments for nuclear…

Instrumentation and Detectors · Physics 2022-11-11 Dan Filipescu

This work aims at carving out more clearly the basic assumptions behind the "track-event theory" (TET) and its derivate radiation action model based on nanodosimetry (RAMN) by clearly distinguishing between effects of tracks at the cellular…

Medical Physics · Physics 2021-11-24 Sonwabile Arthur Ngcezu , Hans Rabus

The effect of electrostatic interactions on the stretching of DNA is investigated using a simple worm like chain model. In the limit of small force there are large conformational fluctuations which are treated using a self-consistent…

Soft Condensed Matter · Physics 2009-10-31 Namkyung Lee , D. Thirumalai

We present high-precision theoretical predictions for the electron energy spectra for the ground-state to ground-state $\beta$ decays of $^{214}$Pb, $^{212}$Pb, and $^{85}$Kr most relevant to the background of liquid xenon dark matter…

High Energy Physics - Experiment · Physics 2020-12-14 Scott Haselschwardt , Joel Kostensalo , Xavier Mougeot , Jouni Suhonen

This paper introduces the use of cable dynamics models as a means to explore the mechanics of DNA on long-length scales. It is on these length scales that DNA forms twisted and curved three-dimensional shapes known as supercoils and loops.…

Biological Physics · Physics 2007-05-23 Sachin Goyal , Todd Lillian , Noel C. Perkins , Edgar Meyhofer
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